Body

PDL-1 antibody could help immune system fight off influenza viral infection, study suggests

An antibody that blocks a component of a key signaling pathway in the respiratory airways could help the immune system rid the body of the influenza virus, a new study suggests. The findings, from a team at The Research Institute at Nationwide Children's Hospital, not only offer a new approach to treating the flu, but also add new information about how the immune system responds to respiratory viral infections.

Johns Hopkins review throws doubt on wound care treatment

A systematic review of 66 research papers focused on the treatment of skin ulcers suggests that most are so technically flawed that their results are unreliable. And even of those that pass muster, there is only weak evidence that some treatments work better than standard compression therapy or special stockings.

Common antibiotic may combat dry eye disease

BOSTON (Dec. 23, 2013) – Meibomian gland dysfunction (MGD) is the leading cause of dry eye disease, which affects tens of millions of Americans. However, there is no FDA-approved treatment for MGD. Researchers from the Schepens Eye Research Institute/Massachusetts Eye and Ear and Harvard Medical School have just identified a potential therapy.

Fewer than 1 in 10 Canadians in ideal cardiovascular health

Fewer than 1 in 10 adult Canadians is in ideal cardiovascular health, according to the new CANHEART health index developed to measure heart health published in CMAJ (Canadian Medical Association Journal).

Cardiovascular disease, which includes heart disease and stroke, is the second leading cause of death in Canada.

1,000-year-old vineyards discovered

Zaballa (Iruña de Oca) was a medieval settlement abandoned in the 15th century. The building of a manor monastery at the heart of it undermined the organisation of the village in the 10th century with the creation of a highly significant rent-seeking system; it was later turned into a veritable factory, a specialised estate in the hands of local lords who, under the auspices of the economic boom in towns like Vitoria-Gasteiz, tried to obtain the maximum profits possible. In the end, the "flight" of its settlers towards the towns caused it to be abandoned.

Beatboxing poses little risk of injury to voice

You might think that beatboxing, with its harsh, high-energy percussive sounds, would be harder on the voice than the sweet song of a soprano. But according to new research by voice expert Dr. H. Steven Sims of the University of Illinois Hospital & Health Sciences System, beatboxing may actually be gentler on the injury-prone vocal cords. His findings were published Dec. 23 online in the Journal of Voice.

Hospital-diagnosed maternal infections linked to increased autism risk

Hospital-diagnosed maternal bacterial infections during pregnancy were associated with an increased risk of autism spectrum disorders in children, according to a Kaiser Permanente study published Dec. 23 in the Journal of Autism and Developmental Disorders.

The research contributes new evidence to a body of scientific literature on the role of infection in autism risk and points to areas for further examination.

Slippery bark protects trees from pine beetle attack, according to CU-Boulder study

Trees with smoother bark are better at repelling attacks by mountain pine beetles, which have difficulty gripping the slippery surface, according to a new study by the University of Colorado Boulder.

The findings, published online in the journal Functional Ecology, may help land managers make decisions about which trees to cull and which to keep in order to best protect forested properties against pine beetle infestation.

GW Cancer Institute defines roles and responsibilities of patient navigators

WASHINGTON (Dec. 23, 2013) – New research out of the George Washington University Cancer Institute (GWCI) defines the roles and responsibilities of patient navigators. With the rapid growth of patient navigation, the paper seeks to develop a framework to describe similarities and differences across navigators and clarify their place in the health care system, leading to greater standardization of the profession.

Role of chronic medical conditions in readmissions

Researchers cite identification and monitoring of known underlying chronic medical conditions as opportunities to reduce readmission rates and improve patient safety.

Antibiotics before heart surgery protect against infection

CHICAGO (December 23, 2013) – A new study found preoperative antibiotic therapy administered within two hours of cardiac surgery decreased the risk of developing surgical site infections (SSIs) significantly. The study was published in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

Infectious diarrhea germs stick to healthcare worker hands

CHICAGO (December 23, 2013) – A new study finds nearly one in four healthcare workers' hands were contaminated with Clostridium difficile spores after routine care of patients infected with the bacteria. The study was published in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

Breast cancer patients experience fewer side effects from anticancer drug

A new analysis has found that both real and sham acupuncture treatments may help alleviate side effects of drugs commonly used to treat breast cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help clinicians improve care for cancer patients. The results also raise the question of whether sham acupuncture is truly inert or may, like real acupuncture, have beneficial effects.

Acupuncture, real or sham, eases hot flashes due to breast cancer chemo

Both real and sham weekly acupuncture treatments eased hot flashes and other side effects of anticancer drug treatment in a small, preliminary study of breast cancer patients, Baltimore researchers have found.

The results, they say, add to previous reports that even the sensation of skin pricks used to simulate genuine acupuncture needle sticks might be enough to generate natural chemicals that improve symptoms.

Both real and 'sham' acupuncture help ease side effects of widely used breast cancer drug

BALTIMORE – December 23, 2013. Breast cancer patients experience fewer side effects while being treated with a widely used drug called an aromatase inhibitor when they get acupuncture – either the real treatment or a "sham" procedure, according to a new study led by researchers at the University of Maryland Marlene and Stewart Greenebaum Cancer Center. Their findings are published online in Cancer, a peer-reviewed journal of the American Cancer Society.