Body

Athens, Ga. - Resistance to chemotherapy is a major problem for those suffering from ovarian cancer--a problem that prevents a cure from a disease dubbed the "silent killer." University of Georgia researchers are giving patients new hope with recent findings that help pinpoint the mechanisms causing chemoresistance.

AURORA, Colo. (Oct. 26, 2015) - An international team of researchers that includes a pediatric anesthesiologist from the University of Colorado School of Medicine and Children's Hospital Colorado is reporting that limited use of general anesthesia with an infant does not cause developmental problems for the child.

The study, published online Sunday in the British medical journal The Lancet, is the largest of its kind and the first randomized study to compare whether general anesthesia in infancy has any effect on neurodevelopmental outcome.

A new and important genetic discovery, which sheds light on how prostate cancers develop and spread, has been made by an international research team led by scientists at The University of Nottingham.

Prostate cancer is one of the most common cancers affecting men. In the UK about one in eight men will develop it at some point in their lives, with older men and those with a family history of prostate cancer most at risk.

Husbands and wives married for a long time don't look at marital problems in the same way. When a marriage has troubles, women worry. They become sad. They get frustrated. For men, it's sheer frustration and not much more.

GALVESTON, Texas - During the last few weeks of a woman's pregnancy, many keep an overnight bag ready to go at a moment's notice in case they begin to go into labor. They do this because there is no clear signal that labor is about to begin - before the body makes it abundantly clear that this process has started. Understanding the mechanisms that initiate this process is especially important when treating women at risk of going into labor early.

Motor proteins that pause at the ends of microtubules and produce pushing forces can also stimulate their growth, according to researchers at Penn State. The proteins' function could be a critical component in understanding cell division and nerve branching and growth.

October 26, 2015 - Research on the genetic factors contributing to neuropathic pain has been hindered by the lack of a standard approach to assessing its clinical characteristics or "phenotype." Now, a report from an expert panel published in the journal PAIN® presents a consensus approach to assessing the phenotype of neuropathic pain.

Among older patients with diabetes whose treatment has resulted in very low hemoglobin A1c (HbA1c) levels or blood pressure values, only 27 percent or fewer underwent medication deintensification, a lost opportunity to reduce overtreatment, according to an article published online by JAMA Internal Medicine.

A program to prevent abusive head trauma (AHT), also known as shaken baby syndrome, was associated with a decline in calls to a nurse advice line but not with a significant change in AHT rates in North Carolina, according to an article published online by JAMA Pediatrics.

AHT is a rare, but severe, form of child maltreatment with severe consequences that can include death or long-term neurological, development and cognitive issues. Infant crying is the most significant trigger of AHT.

ANN ARBOR, Mich. -- Anyone who takes medicine to get their blood sugar or blood pressure down - or both - knows their doctor prescribed it to help them.

But what if stopping, or at least cutting back on, such drugs could help even more?

In some older people, that may be the safer route. But two new studies published in JAMA Internal Medicine suggest doctors and patients should work together to backpedal such treatment more often.

CHAPEL HILL, N.C. -- A new evaluation of a statewide shaken baby prevention effort found that the number of calls to a nurse advice line from North Carolina parents who called because of a crying baby were reduced in the first 2 years after the intervention was implemented in 2007.

However, the study, published Oct. 26, 2015 in JAMA Pediatrics, did not find a statistically significant reduction in the number of abusive head trauma (AHT) or "shaken baby" cases in North Carolina during the same period.

Females have more sexual partners when they live in colder climates and are happier being monogamous when it is hotter, a study into the behaviour of insects has found.

Researchers at the University of Exeter also found that some female fruit flies are genetically programmed to have a large number of mates and will do so whatever the weather, while others will consistently stick to one mate.

Vitamin D is important for the absorption and metabolism of calcium, as well as for maintaining healthy bones and muscles. Danes generally have too low a level, and this is mainly because the sun - the main source - is absent for much of the year.

Getting an intake of vitamin D through the diet will therefore be relevant for many, but are consumers actually interested in buying foods with added vitamin D?

A new article published in Regenerative Medicine reviews the latest advances in magnetic particle tracking in cell therapy, a potentially groundbreaking strategy in disease treatment and regenerative medicine.

Cell therapy is one of the most promising avenues for regenerative medicine, however, its success is restricted by a number of limitations, such as inefficient delivery and retention of the therapeutic cells at the target organ, difficulties in monitoring the safety and efficacy of the therapy, in addition to issues obtaining and maintaining therapeutic cell phenotypes.

As manufacturers well know, the nuances of interpersonal relationships are writ large in the context of sales channel partner programs, and knowing how to manage them is a surprisingly delicate business. A paper forthcoming in the December 2015 issue of the Journal of Retailing describes just how nuanced the back and forth can be as companies seek to incentivize but not alienate their partners.