Body

• Goal of clinical trials by 2017
• Uncontrolled movements hurt quality of life for Parkinson's patients
• International search to find drug to reduce movements
• Parkinson's affects 1 million in U.S., expected to double by 2030

CHICAGO --- In an international study, Northwestern Medicine scientists and colleagues have identified a novel strategy for reducing the side effects of uncontrolled movement caused by the drug levodopa, commonly used to treat the stiffness, tremors and poor muscle control of Parkinson's disease.

Baltimore, MD, November 17, 2015--A clinical trial of a new Ebola vaccine (ChAd3-EBO-Z) that resulted from an unprecedented global consortium assembled at the behest of the World Health Organization has found that it is well tolerated and stimulates strong immune responses in adults in Mali, West Africa and in the US, according to a study published in the latest issue of the journal Lancet Infectious Disease.

A University of Colorado Cancer Center study published in the journal Breast Cancer Research and Treatment shows that breast cancer patients whose health insurance plans included prescription drug benefits were 10 percent more likely to start important hormonal therapy than patients who did not have prescription drug coverage. Women with household income below $40,000 were less than half as likely as women with annual household income greater than $70,000 to continue hormonal therapy.

Called after Tolkien's character from the "Lord of the Rings" series, a new eyeless harvestman species was found to crawl in a humid cave in southeastern Brazil. Never getting out of its subterranean home, the new daddy longlegs species is the most highly modified representative among its close relatives and only the second one with no eyes living in Brazil. Its introduction to science, made by the Brazilian research team of Dr. Ricardo Pinto-da-Rocha, Instituto de Biociências da Universidade de São Paulo together with Dr.

Children are taught that all living organisms -- from animals, plants, and fungi to bacteria and single-celled organisms -- belong to specifically different categories of organic life. A new discovery by Tel Aviv University researchers and international collaborators is poised to redefine the very criteria used to define and classify these animals.

Researchers have found that a close cousin of the jellyfish has evolved over time into a microscopic parasite. The finding represents the first case of extreme evolutionary degeneration of an animal body.

The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on developing vaccines, but there is still a need for antiviral therapies to protect health care workers and local populations in the event of future outbreaks.

Amsterdam, Nov. 18, 2015 - Journal Maturitas today announced the publication of a position statement by the European Menopause and Andropause Society (EMAS) covering testosterone replacement therapy in the aging male.

TAMPA, Fla. (Nov. 18, 2015) - Advancements in precision medicine have led to many new targeted cancer therapies for cancer patients. These treatments focus on using agents that target one or two genes that contribute to tumor development. The approach tends to be more effective against cancer cells and less toxic toward normal cells than standard chemotherapeutic regimens.

A team from the University of York has published research unveiling the 3-D structure of human heparanase, a sugar-degrading enzyme which has received significant attention as a key target in anti-cancer treatments.

Though naturally regulated in a healthy organism, heparanase is an enzyme which is produced in excessive quantities in a cancer situation. The sugar-degrading activity of this excess heparanase leads to exaggerated degradation of the sugars in the extracellular 'matrix' (the molecules surrounding cells), making it easier for cancer cells to proliferate.

DURHAM, N.C. - Parents' fears about their teenagers' heavy use of cell phones and social media may be exaggerated, according to a new report from Duke University researchers. However, there are important exceptions in the areas of cyberbullying and sleep disruption.

Often avoiding sampling gear with their capability to detect movements and swim their way out of the nets fast enough, the small squids living in the open-ocean zone have so long gone under-researched. The present study, conducted by Dr. Michel Hendrickx, Universidad Nacional Autonoma de Mexico, and his team, seems to provide new and first distributional records of five such species for the Gulf of California and in southwestern Mexico.

HOUSTON - (Nov. 18, 2015) - Trade and financial shocks in the form of collapsing commodity prices and reduced availability of external financing have worsened Latin America's economic prospects in the past year, according to an issue brief from Rice University's Baker Institute for Public Policy. South America, in particular, is expected to perform poorly into 2016, the brief predicts.

The supreme importance of water and sanitation to development and well-being merits creation of a powerful new global arena inside the UN, dedicated to resolving water conflicts and common challenges while tracking progress against the world's newly-agreed development goals.

While socioeconomic factors such as race, ethnicity, marital status, insurance status, and geographic location are associated with whether patients with localized pancreatic cancer undergo resection (surgical removal of the tumor), only geographic location is associated with survival in these patients, according to a study published online by JAMA Surgery.

BOSTON (Nov. 18, 2015; 11:00 a.m. EST)--A new inter-disciplinary study led by researchers at Tufts University found that coconut oil effectively controlled the overgrowth of a fungal pathogen called Candida albicans (C. albicans) in mice. In humans, high levels of C. albicans in the gastrointestinal tract can lead to bloodstream infections, including invasive candidiasis. The research, published in mSphere, suggests that it might be possible to use dietary approaches as an alternative to antifungal drugs in order to decrease the risk of infections caused by C.