Body

Tiny plants could cut costs, shrink environmental footprint

WEST LAFAYETTE, Ind. - Tall, waving corn fields that line Midwestern roads may one day be replaced by dwarfed versions that require less water, fertilizer and other inputs, thanks to a fungicide commonly used on golf courses.

Burkhard Schulz, a Purdue University assistant professor of plant biochemical and molecular genetics, had earlier found that knocking out the steroid function in corn plants would create tiny versions that only had female sex characteristics. But brassinazole, the chemical used to inhibit the plant steroid biosynthesis, was prohibitively expensive.

Study examines BI-RADS and MRI in predicting breast cancer

OAK BROOK, Ill. – A large, multicenter study found that the Breast Imaging and Reporting Data Systems (BI-RADS) terminology used by radiologists to classify breast imaging results is useful in predicting malignancy in breast lesions detected with MRI. Results of the study are published online in the journal Radiology.

Early biomarker for pancreatic cancer identified

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have identified a new biomarker and therapeutic target for pancreatic cancer, an often-fatal disease for which there is currently no reliable method for early detection or therapeutic intervention. The paper will be published May 15 in Cancer Research.

'Fertilizing' bone marrow helps answer why some cancers spread to bones

ANN ARBOR, Mich.—Researchers found that administering a common chemotherapy drug before bone tumors took root actually fertilized the bone marrow, enabling cancer cells, once introduced, to seed and grow more easily.

The findings provide valuable insight as to why some cancers metastasize to bone, and could eventually result in new metastasis-prevention drugs, said Laurie McCauley, professor in the Department of Periodontics and Oral Medicine at the University of Michigan School of Dentistry and principal investigator on the study.

Delivery system for gene therapy may help treat arthritis

AUGUSTA, Ga. – A DNA-covered submicroscopic bead used to deliver genes or drugs directly into cells to treat disease appears to have therapeutic value just by showing up, researchers report.

Within a few hours of injecting empty-handed DNA nanoparticles, Georgia Health Sciences University researchers were surprised to see increased expression of an enzyme that calms the immune response.

CNIO scientists successfully test the first gene therapy against aging-associated decline

A number of studies have shown that it is possible to lengthen the average life of individuals of many species, including mammals, by acting on specific genes. To date, however, this has meant altering the animals' genes permanently from the embryonic stage – an approach impracticable in humans. Researchers at the Spanish National Cancer Research Centre (CNIO), led by its director María Blasco, have proved that mouse lifespan can be extended by the application in adult life of a single treatment acting directly on the animal's genes.

Laxative-free CT colonography may be as accurate as colonoscopy in detecting high-risk polyps

A CT-scan-based form of virtual colonoscopy that does not require laxative preparation appears to be as effective as standard colonoscopy in identifying the intestinal polyps most likely to become cancerous. In the May 15 issue of Annals of Internal Medicine, a Massachusetts General Hospital (MGH)-based research team reports finding that the new technique, which uses computer-aided systems both to virtually cleanse and to analyze the images acquired, was able to identify more than 90 percent of the common polyps called adenomas that were 10 mm or larger.

Colon cancer risk when a first-degree relative has precancerous polyps is not clear

INDIANAPOLIS -- Current colorectal cancer screening guidelines for individuals with first-degree relatives with precancerous colon polyps are based on studies that were not properly designed or were too limited to shape those guidelines, according to a new systemic review of research on the topic. The review authors call for new studies to measure the risk and identify the factors that modify it.

Physical fitness may reduce hypertension risk in people with family history

If your parents have a history of high blood pressure, you can significantly reduce your risk of developing the disease with moderate exercise and increased cardiovascular fitness, according to new research in the American Heart Association's journal Hypertension.

In a study of more than 6,000 people, those who had a parent with high blood pressure but were highly fit had a 34 percent lower risk of developing high blood pressure themselves, compared to those with a low-fitness level who had the same parental history.

Sleepwalking more prevalent among US adults than previously suspected, Stanford researcher says

STANFORD, Calif. — What goes bump in the night? In many U.S. households: people. That's according to new Stanford University School of Medicine research, which found that about 3.6 percent of U.S. adults - or upward of 8.4 million - are prone to sleepwalking. The work also showed an association between nocturnal wanderings and certain psychiatric disorders, such as depression and anxiety.

The study, the researchers noted, "underscores the fact that sleepwalking is much more prevalent in adults than previously appreciated."

Genetic test identifies eye cancer tumors likely to spread

Lawrence Livermore work may improve the efficiency of the biofuel production cycle

By deciphering the makeup of a bacterium found in the soil of a tropical rain forest, scientists may have a better understanding of how to more efficiently produce biofuels.

The production of liquid fuels derived from plant biomass offers a promising technology for reducing greenhouse gas emissions and dependence on fossil fuels.

Religion replenishes self-control

There are many theories about why religion exists, most of them unproven. Now, in an article published in Psychological Science, a journal of the Association for Psychological Science, psychologist Kevin Rounding of Queen's University, Ontario, offers a new idea, and some preliminary evidence to back it up.

The primary purpose of religious belief is to enhance the basic cognitive process of self-control, says Rounding, which in turn promotes any number of valuable social behaviors.

Growing risks from hatchery fish

Portland, Oregon – May 14, 2012 -- A newly published collection of more than 20 studies by leading university scientists and government fishery researchers in Alaska, British Columbia, Washington, Oregon, California, Russia and Japan provides mounting evidence that salmon raised in man-made hatcheries can harm wild salmon through competition for food and habitat.

Anthropologists discover earliest form of wall art

Anthropologists working in southern France have determined that a 1.5 metric ton block of engraved limestone constitutes the earliest evidence of wall art. Their research, reported in the most recent edition of the Proceedings of the National Academy of Sciences, shows the piece to be approximately 37,000 years old and offers rich evidence of the role art played in the daily lives of Early Aurignacian humans.