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Down syndrome: Identification of differential proteins in maternal serum

Prenatal screening for Down syndrome (DS) is still in need of improvement. Perinatal medicine experts have worked hard to find new biomarkers for screening of DS. Dr. Shi he Shao and his co-investigators, from Jiangsu University and Changzhou Woman and Children Health Hospital, report in the May 2012 issue of Experimental Biology and Medicine that they have successfully identified twenty-nine differentially expressed proteins in maternal serum from pregnancies carrying DS fetuses with proteomic approaches.

Scientists find that rain may not always be a welcome thing to waterbirds

Scientists from the Smithsonian and colleagues have found that waterbird communities can be the "canary in the coal mine" when it comes to detecting the health of urban estuary ecosystems. Their research revealed that the types of waterbirds that inhabit urban estuaries are influenced not only by urban development, but also by a far more natural process―rain. The team's findings are published in the scientific journal PLoS ONE.

Experts call for strong regulation and peer review of military and civilian nuclear programs

All nuclear energy and weapons programs should be independently regulated and subject to rigorous peer review, according to three experts on nuclear policy. Their comments and recommendations are published in an article entitled, "A Safer Nuclear Enterprise," in the June 8 issue of the journal Science.

The authors noted that, despite international diplomatic efforts to prevent the proliferation of nuclear weapons and ensure that nuclear material is protected against theft, there is growing apprehension about terrorists acquiring weapons or nuclear material.

Armored caterpillar could inspire new body armor

RIVERSIDE, Calif. (www.ucr.edu) — Military body armor and vehicle and aircraft frames could be transformed by incorporating the unique structure of the club-like arm of a crustacean that looks like an armored caterpillar, according to findings by a team of researchers at the University of California, Riverside's Bourns College of Engineering and elsewhere published online today, June 7, in the journal Science.

Highly contagious honey bee virus transmitted by mites

Researchers in Hawaii and the UK report that the parasitic 'Varroa' mite has caused the Deformed Wing Virus (DWV) to proliferate in honey bee colonies. This association is now thought to contribute to the world-wide spread and probable death of millions of honey bee colonies. The current monetary value of honey bees as commercial pollinators in the United States alone is estimated at about $15-$20 billion annually

New discovery provides insight on long-standing pregnancy mystery

NEW YORK, June 7, 2012 – Researchers at NYU School of Medicine have made an important discovery that partially answers the long-standing question of why a mother's immune system does not reject a developing fetus as foreign tissue.

An important breakthrough in immunology by IRCM researchers

A team of researchers at the IRCM led by Dr. André Veillette made an important breakthrough in the field of immunology, which will be published online today by the scientific journal Immunity. The scientists explained a poorly understood molecular mechanism associated with a human immune disorder known as XLP disease or Duncan's syndrome.

Finding ways to feed pigs for less

Results of a preliminary experiment conducted at the University of Illinois indicate that it may be possible to select pigs that can make efficient use of energy in less expensive feed ingredients, thus reducing diet costs.

New data suggests HIV superinfection rate comparable to initial HIV infection

Human immunodeficiency virus (HIV) superinfection may be as common as initial HIV infection and is not limited to high risk-populations, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the National Institute of Allergy and Infectious Diseases (NIAID). In the first large-scale study of HIV superinfection in a general heterosexual population, researchers examined the rate of superinfection among a community of sub-Saharan adults.

HIV superinfection in Uganda may be more common than previously thought, study finds

HIV superinfection, when a person with HIV could acquire a second, new strain of HIV, may occur as often as initial HIV infection in the general population in Uganda, a study suggests.

Newly identified protein function protects cells during injury

CINCINNATI – Scientists have discovered a new function for a protein that protects cells during injury and could eventually translate into treatment for conditions ranging from cardiovascular disease to Alzheimer's.

Researchers report online June 7 in the journal Cell that a type of protein called thrombospondin activates a protective pathway that prevents heart cell damage in mice undergoing simulated extreme hypertension, cardiac pressure overload and heart attack.

Manipulating chromatin loops to regulate genes may offer future treatments for blood diseases

In exploring how proteins interact with crucial DNA sequences to regulate gene activity, researchers have shed light on key biological events that may eventually be manipulated to provide new disease treatments.

Steel-strength plastics -- and green, too!

As landfills overflow with discarded plastics, scientists have been working to produce a biodegradable alternative that will reduce pollution. Now a Tel Aviv University researcher is giving the quest for environmentally friendly plastics an entirely new dimension — by making them tougher than ever before.

Helping adolescents root out stigma associated with mental illness

Health experts agree that reducing the stigma associated with adolescent mental illness is an essential step toward increasing the number of teenagers who seek the help they need.

But, say researchers at Case Western Reserve in the Journal of Nursing Measurement, the relative dearth of data regarding stigma in this age group makes tackling the topic particularly tough. Not only is adolescent mental health stigma rarely studied, but even less is known about the accuracy of measures used to assess it.

Mount Sinai researchers develop a multi-target approach to treating tumors

Researchers from Mount Sinai School of Medicine developed a cancer model built in the fruit fly Drosophila, then used it to create a whole new approach to the discovery of cancer treatments. The result is an investigational compound AD80 that precisely targets multiple cancer genes. Tested in mouse models, the drug proved far more effective and less toxic than standard cancer drugs, which generally focus on a single target. This is the first time that whole-animal screening has been used in a rational, step-wise approach to polypharmacology.