Body

For years, scientists have been looking for a good source of heart cells that can be used to study cardiac function in the lab, or perhaps even to replace diseased or damaged tissue in heart disease patients. To do this, many are looking to stem cells. Researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham), the Human BioMolecular Research Institute, and ChemRegen, Inc. have been searching for molecules that convert stem cells to heart cells and now they've found one.

Durham, NC — A new study of North American songbirds reveals that birds that live with fluctuating weather are more flexible singers.

Mixing it up helps birds ensure that their songs are heard no matter what the habitat, say researchers at Australian National University and the National Evolutionary Synthesis Center.

To test the idea, the researchers analyzed song recordings from more than 400 male birds spanning 44 species of North American songbirds — a data set that included orioles, blackbirds, warblers, sparrows, cardinals, finches, chickadees and thrushes.

Genes that allow our immune system to tell the difference between our own cells and foreign invaders are evolving much more rapidly than previously thought, according to an article online on August 3rd in Trends in Genetics. The resulting degree of variation improves our ability to fight off disease, but could also present challenges to current worldwide efforts aimed at identifying potential donors for patients undergoing stem cell transplantation.

HEIDELBERG, 3 August 2012 – Intellectual disability due to Fragile X and Down syndromes involves similar molecular pathways report researchers in The EMBO Journal. The two disorders share disturbances in the molecular events that regulate the way nerve cells develop dendritic spines, the small extensions found on the surface of nerve cells that are crucial for communication in the brain.

Researchers at Mount Sinai School of Medicine, the University of Manchester, and the MD Anderson Cancer Center have found a new role for an oncogenic signaling pathway in embryonic stem cell (ESC) self-renewal and in reprogramming adult cells into an ESC-state, which will aid in the development of future cancer therapies.

Peter de Groot (Biology) hopes his recent finding confirming the extinction of the Javan rhinoceros in Vietnam pushes the public to protect the last remaining group of these prehistoric creatures living in Indonesia.

"We still have a chance to save the species but before we do anything, we have to determine the profile of the remaining group," he says.

Double-stranded DNA has often been described as a right-handed helical structure, known as B-DNA. To perform its multiple functions, double-stranded DNA has multiple structures depending on conditions. For example, the melted DNA bubble forms during transcription elongation and the left-handed helical Z-DNA forms hypothetically during transcriptional regulations.

Acute liver failure is a life-threatening disease, characterized by a sudden, massive death of liver cells. Unfortunately, few treatment options exist, especially for advanced-stage liver failure. As a last resort a liver transplant may be the only remaining option. Now the physician Dr. Junfeng An of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and Dr. Stefan Donath, a specialist in internal medicine and cardiology, also of the MDC and Helios Klinikum Berlin-Buch, have developed a new treatment approach based on a mouse model.

EAST LANSING, Mich. — Parents get physical with their misbehaving children in public much more than they show in laboratory experiments and acknowledge in surveys, according to one of the first real-world studies of caregiver discipline.

The study, led by Michigan State University's Kathy Stansbury, found that 23 percent of youngsters received some type of "negative touch" when they failed to comply with a parental request in public places such as restaurants and parks. Negative touch included arm pulling, pinching, slapping and spanking.

ANN ARBOR, Mich.—Predatory beetles can detect the unique alarm signal released by ants that are under attack by parasitic flies, and the beetles use those overheard conversations to guide their search for safe egg-laying sites on coffee bushes.

Why do adults continue to play throughout their lives while most other mature mammals cease such behavior? According to researchers at Penn State, playfulness may serve an evolutionary role in human mating preferences by signaling positive qualities to potential long-term mates.

Elephants can communicate using very low frequency sounds, with pitches below the range of human hearing. These low-frequency sounds, termed "infrasounds", can travel several kilometers, and provide elephants with a "private" communication channel that plays an important role in elephants' complex social life. Their frequencies are as low as the lowest notes of a pipe organ.

African elephants are in the Amboseli National Park, Kenia.

The beautiful, endemic and endangered cycad, Cycas micronesica was once a dominant forest tree on the island of Guam, but recent plant mortality predicts extirpation from Guam habitats by 2019. This dire prediction by scientists at the Western Pacific Tropical Research Center (WPTRC), University of Guam is validated by the research of Thomas E. Marler and John H. Lawrence, which has concluded that Cycas micronesica is the only native host for the invasive scale insect Aulacaspis yasumatsui.

An experiment has shown that strawberry extract added to skin cell cultures acts as a protector against ultraviolet radiation as well as increasing its viability and reducing damage to DNA. Developed by a team of Italian and Spanish researchers, the study opens the door to the creation of photoprotective cream made from strawberries.

CHICAGO --- A new paper just published in the Journal of Bioethical Inquiry uses extensive Freedom of Information Act findings to detail an extremely troubling off-label medical intervention employed in the U.S. on pregnant women to intentionally engineer the development of their fetuses for sex normalization purposes.