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Rhode Island Hospital reduces incidence of hospital-associated C. difficile by 70 percent

PROVIDENCE, R.I. – Rhode Island Hospital has reduced the incidence of hospital-associated Clostridium difficile (C. difficile) infections by 70 percent and reduced annual associated mortality in patients with hospital-associated C. difficile by 64 percent through successive implementation of five rigorous interventions , as reported in the July 2013 issue of The Joint Commission Journal on Quality and Patient Safety.

Lab reproduction of a marine compound with antibiotic properties

Bacterial resistance to drugs leads pharmaceutical labs to be in constant search for new antibiotics to treat the same diseases. For the last thirty years, the sea bottom has yielded a wealth of substances with properties of interest to the pharmaceutical industry. Isolated from a marine microorganism off the coast of Alicante by the company BioMar, baringolin shows promising antibiotic activity at a very low concentration.

Recent progress in gene-sensing strategies for rapid detection of foodborne pathogens

Food is the basis of human survival and development, and its safety is an important issue for people's livelihood, and also an important indicator to measure the quality of people's lives in a country. The statistics showed that the main factor of Chinese food poisoning remained to be microbial pathogens, ranking before the chemical toxin. In food contamination, some common and highly pathogenic pathogens include Listeria monocytogenes, Vibrio parahaemolyticus, Norwalk and Rotavirus, which are the culprit cause of food poisoning.

The sun moth: A beautiful new species Stenoloba solaris from China

Scientist describe a new striking species of moth from China with an engaging wing pattern. The new species Stenoloba solaris has its name inspired by the orange circular patch on its wings that resembles the rising sun. The study was published in the open access journal Zookeys.

Children from the poorest families are twice as likely to contract malaria than the least poor

The collaborative study, led by Durham University and the London School of Hygiene &Tropical Medicine, is published today in The Lancet and unusually brings together the health and development communities.Half the world's population is at risk from malaria. A review of studies from different locations across the world with risk factors for the disease showed clearly that in these impoverished communities, the risk of malaria was doubled in the poorest children compared with the least poor.

Researchers identify 'master coordinator' for aortic rupture

Every year, more than 16,000 Americans die as a result of what's known as an "aortic dissection" — a catastrophic rupture of the aorta, the body's largest artery. Once thought to be a simple structural failure, aortic dissection is now understood to be caused by an inflammatory process that weakens the artery's walls.

Current global food production trajectory won't meet 2050 needs

Crop yields worldwide are not increasing quickly enough to support estimated global needs in 2050, according to a study published June 19 in the open access journal PLOS ONE by research associate Deepak Ray and colleagues from the Institute on the Environment (IonE) at the University of Minnesota.

Protected areas provide African birds with stepping stones to survival

The protected area network in Tanzania is playing a vital role in the survival of savannah bird species as they move west in response to climate and environmental changes, according to new research led by the University of York.

Using data on savannah birds from the Tanzanian Bird Atlas project - which has documented Tanzanian bird distributions over recent decades - the researchers found that they are using protected areas as stepping stones as they move to areas further west where dry seasons are getting longer, with movements of up to 300km noted.

Snail genetic tracks reveal ancient human migration

Some snails in Ireland and the Pyrenees are genetically almost identical, perhaps because they were carried across the Atlantic during an 8000-year-old human migration. The snail genetics tie in with studies of human genetics and the colonization of Ireland, according to the research published June 19 in the open access journal PLOS ONE by Angus Davison and colleagues from the University of Nottingham, UK.

Flu shot likely prevented 13 million illnesses, 110,000 hospitalizations from 2005-2011

Approximately 13 million illnesses and over 110,00 hospitalizations may have been averted by the flu vaccine over the last 6 years in the U.S, according to calculations published June 19 in the open access journal PLOS ONE by Deliana Kostova and colleagues from the U.S Centers for Disease Control and Prevention.

Yield trends insufficient to double global crop production by 2050

Crop yields worldwide are not increasing quickly enough to support estimated global needs in 2050, according to a study published June 19 in the open access journal PLOS ONE by Deepak Ray and colleagues from the Institute on the Environment (IonE) at the University of Minnesota.

Better guidance urgently needed for 'epidemic' of sleep apnea in surgical patients

Although as many as 25 percent of patients undergoing surgery suffer from sleep apnea, few hospitals have policies to help manage the risks of this condition during surgery, and there is little evidence to help guide anesthesiologists and surgeons caring for these patients. In a new editorial in the New England Journal of Medicine, Stavros Memtsoudis, M.D., Ph.D., director of Critical Care Services at Hospital for Special Surgery, New York City, calls for a new research initiative to identify the safest and most effective ways to manage patients with sleep apnea.

Drug shows surprising efficacy as treatment for chronic leukemia, mantle cell lymphoma

COLUMBUS, Ohio – Two clinical studies published in the New England Journal of Medicine with an accompanying editorial suggest that the novel agent ibrutinib shows real potential as a safe, effective, targeted treatment for adults with chronic lymphocytic leukemia (CLL) and for patients with mantle cell lymphoma (MCL).

Ibrutinib continues strong showing against mantle cell lymphoma

HOUSTON - In a major international study led by researchers at The University of Texas MD Anderson Cancer Center, the targeted therapy ibrutinib continues to show remarkable promise for the treatment of relapsed or refractory mantle cell lymphoma (MCL).

The most recent interim findings of the 18-center Phase 2 study were published today in the New England Journal of Medicine. Previous interim findings were presented in December 2012 at the 54th American Society of Hematology Annual Meeting and Exposition.

Unprecedented results, fewer side effects

Evolution of an outbreak: Complications from contaminated steroid injections

(SACRAMENTO, Calif.) — A study of the patients who received injections of steroids contaminated with the fungus Exserohilum rostratum from the New England Compounding Center has found that some patients had fungal infections even though they did not experience a worsening of their symptoms and that magnetic resonance imaging (MRI) can help detect infection, especially among those individuals who received injections from highly contaminated lots.