Body

Gene variant increases risk of kidney disease in African-Americans

African-Americans with two copies of the APOL1 gene have about a 4 percent lifetime risk of developing a form of kidney disease, according to scientists at the National Institutes of Health. The finding brings scientists closer to understanding why African-Americans are four times more likely to develop kidney failure than whites, as they reported in the Oct. 13 online edition of the Journal of the American Society of Nephrology.

Taking the pulse of charge-separation processes

The use of organic photovoltaics for the production of electricity from sunlight offers an attractive and promising basis for an innovative and environmentally friendly means of energy supply. They can be manufactured quite economically and, because they are as bendable as plastic wrap, they can be processed flexibly. The problem is that they are yet markedly less efficient than conventional inorganic semiconductor cells. The most crucial process in the conversion of light into electric current is the generation of free charge carriers.

Unraveling the mysteries of the natural killer within us

Scientists have discovered more about the intricacies of the immune system in a breakthrough that may help combat viral infections such as HIV.

Co-led by Professor Jamie Rossjohn of Monash University and Associate Professor Andrew Brooks from University of Melbourne, an international team of scientists have discovered more about the critical role Natural Killer cells play in the body's innate immune response.

The findings were published today in Nature.

Life beyond cancer: Starting a family following treatment

CHICAGO - Five years ago, Sheri Scott was beginning a new chapter in her life. The recently engaged 31-year-old was eagerly browsing bridal magazines and busy planning for her big day. Unfortunately, just weeks following her engagement, Scott was diagnosed with breast cancer. Suddenly, she was juggling medical appointments and planning a double mastectomy instead of a wedding. Soon after her diagnosis, Scott was approached by her doctor at Northwestern Memorial Hospital about preserving her fertility.

Heart surgeons-in-training benefit from hands-on homework

Vancouver – Residents in cardiac surgery who receive extra training on a take-home simulator do a better job once they get into the operating room, Dr. Buu-Khanh Lam today told the Canadian Cardiovascular Congress 2011, co-hosted by the Heart and Stroke Foundation and the Canadian Cardiovascular Society.

Advanced post-mastectomy breast reconstruction improves women's psychosocial and sexual well-being

After a mastectomy, women who undergo breast reconstruction with tissue from their own abdomen experience significant gains in psychological, social, and sexual wellbeing as soon as three weeks after surgery. That is one of the conclusions of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The study's results provide new information to breast cancer survivors who are contemplating these types of breast reconstruction procedures.

Survey finds public support for geoengineering research

Research on geoengineering appears to have broad public support, as a new, internationally-representative survey revealed that 72 per cent of respondents approved research into the climate-manipulating technique.

The study, published today, 24 October, in IOP Publishing's journal Environmental Research Letters, is the first international survey on public perception of geoengineering and solar radiation management (SRM) and shows that these terms are becoming increasingly embedded into public discourse.

Liver parasite lacks key genes for fatty acid synthesis: Genome sequencing of Clonorchis sinensis

The human liver fluke Clonorchis sinensis affects more than 35 million people in South East Asia and 15 million in China. Infection by this parasite causes clonorchiasis. Repeated or chronic infection can lead to serious disease of the liver, gall bladder or bile ducts, including the frequently fatal bile duct cancer - cholangiocarcinoma (CCA). The complete genome sequence the genome of C.

NSAID use associated with lower colorectal cancer mortality rates among postmenopausal women

BOSTON — Postmenopausal women who reported having used nonsteroidal anti-inflammatory drugs for at least 10 years at the time of enrollment in the Women's Health Initiative study had a lower risk for death from colorectal cancer compared with women who reported no use of these drugs at enrollment, according to data presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011.

Significant weight gain in adulthood increased risk for endometrial cancer

BOSTON — Postmenopausal women who gained weight during adulthood had an increased risk for endometrial cancer compared with women who maintained a stable weight, according to data from the American Cancer Society's Cancer Prevention Study II Nutrition Cohort.

Victoria L. Stevens, Ph.D., strategic director of laboratory services at the National Home Office of the American Cancer Society in Atlanta, presented the data at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011.

Sleeping sickness drug may provide long-term protection against skin cancer

BOSTON — An antiparasitic agent used to treat African sleeping sickness might someday be used to prevent nonmelanoma skin cancers. Researchers found that DFMO, or α-difluoromethylornithine, still appeared to protect against nonmelanoma skin cancers years after people stopped taking the drug, according to a poster presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011.

Body weight, diet may be risk factors for non-Hodgkin lymphoma

BOSTON — Body weight in young adulthood and diet appeared to be associated with the risk for non-Hodgkin lymphoma, according to results presented at the 10th AACR International Conference on Frontiers in Cancer Prevention Research, held Oct. 22-25, 2011.

"The causes of non-Hodgkin lymphoma (NHL) are poorly understood, and unfortunately, we don't know very much about specific ways to prevent or lower the risk for this disease," said Kimberly Bertrand, Sc.D., research fellow in the department of epidemiology at the Harvard School of Public Health.

Breakthrough in the production of flood-tolerant crops

This week thousands of families lost their homes and crops as flood waters swept across Central America. In Thailand huge tracts of farmland were submerged as the country faced its worst flooding in 50 years. Across the globe agricultural production is at risk as catastrophic flooding becomes a world-wide problem.

Manchester's 'first step' to perfect drug combinations

The researchers found a way of identifying ideal drug combinations from billions of others which would prevent inflammation from occurring.

The findings, published in Nature Chemical Biology, could be the first step in the development of new drug combinations to combat severe diseases and conditions.

Most non-infectious disease, such as cancer, stroke and Alzheimer's are worsened by inflammation, which is the body's natural defence mechanism.

Bioengineered protein shows preliminary promise as new therapy for hemophilia

A genetically engineered clotting factor that controlled hemophilia in an animal study offers a novel potential treatment for human hemophilia and a broad range of other bleeding problems.