Body

Breast tomosynthesis increases cancer detection and reduces recall rates

CHICAGO – Researchers have found that digital breast tomosynthesis (DBT) led to reduced recall rates and an increase in cancer detection in a large breast cancer screening program. The results of this study were presented today at the annual meeting of the Radiological Society of North America (RSNA).

Breast cancer risk related to changes in breast density as women age

CHICAGO – Automated breast density measurement is predictive of breast cancer risk in younger women, and that risk may be related to the rate at which breast density changes in some women as they age, according to research being presented today at the annual meeting of the Radiological Society of North America (RSNA).

3D mammography increases cancer detection and reduces call-back rates, Penn study finds

CHICAGO—Compared to traditional mammography, 3D mammography—known as digital breast tomosynthesis—found 22 percent more breast cancers and led to fewer call backs in a large screening study at the Hospital of the University of Pennsylvania (HUP), researchers reported today at the annual meeting of the Radiological Society of North America (RSNA).

Embargoed news from Annals of Internal Medicine -- 'Overweight and healthy' is a myth

1. Evidence suggests that "healthy and overweight" is a myth

Researchers turn to machines to identify breast cancer type

(Edmonton) Researchers from the University of Alberta and Alberta Health Services have created a computer algorithm that successfully predicts whether estrogen is sending signals to cancer cells to grow into tumours in the breast. By finding this hormone receptor, known as estrogen receptor positive, physicians can prescribe anti-estrogen drug therapies, improving patient outcomes.

New technique identifies pathogens in patient samples faster, in great detail

A team of Danish investigators has shown how to identify pathogens faster, directly from clinical samples. The research, published online ahead of print in the Journal of Clinical Microbiology appears in the journal's January 2014 issue.

The investigators used a technique known as whole genome sequencing to identify and completely characterize bacteria causing urinary tract infections. In just 18 hours, they identified the culprit microorganisms, characterized the pathogens' patterns of antibiotic susceptibility, and identified specific strains.

Genetic mutation may play key role in risk of lethal prostate cancer in overweight patients

Boston, MA — Obesity is associated with a worse prostate cancer prognosis among men whose tumors contain a specific genetic mutation, suggest results from a new study led by Harvard School of Public Health (HSPH), Dana-Farber Cancer Institute and Brigham and Women's Hospital researchers. Among prostate cancer patients whose tumors contain the mutation, they had a more than 50% increased risk of dying from prostate cancer if they were overweight or obese compared to healthy-weight men; among men whose tumors did not have the mutation, there was no effect of obesity on cancer survival.

Burmese python genome reveals extreme adaptation

AURORA, Colo. (Dec. 2, 2013) – Scientists from the University of Colorado School of Medicine who sequenced the genome of the Burmese python have discovered large numbers of rapidly evolved genes in snakes.

These genetic changes are linked to extreme characteristics in snakes, such as rapid increases in metabolism and organ growth after feeding, findings that open a novel window into how evolution works at the molecular level.

Secrets to 'extreme adaptation' found in Burmese python genome

The Burmese python's ability to ramp up its metabolism and enlarge its organs to swallow and digest prey whole can be traced to unusually rapid evolution and specialized adaptations of its genes and the way they work, an international team of biologists says in a new paper.

Researchers revise Darwin's thinking on invasive species

PULLMAN, Wash.-For more than a century and a half, researchers interested in invasive species have looked to Charles Darwin and what has come to be called his "naturalization conundrum." If an invader is closely related to species in a new area, he wrote in his landmark The Origin of Species, it should find a more welcoming habitat. On the other hand, it could expect competition from the related species and attacks from its natural enemies like predators and parasites.

What makes the deadliest form of malaria specific to people?

Researchers have discovered why the parasite that causes the deadliest form of malaria only infects humans.

Arctic study shows key marine food web species at risk from increasing CO2

A research expedition to the Arctic, as part of the Catlin Arctic Survey, has revealed that tiny crustaceans, known as copepods, that live just beneath the ocean surface are likely to battle for survival if ocean acidity continues to rise. The study found that copepods that move large distances, migrating vertically across a wide range of pH conditions, have a better chance of surviving.

How bacteria respond so quickly to external changes

Understanding how bacteria adapt so quickly to changes in their external environment with continued high growth rates is one of the major research challenges in molecular microbiology. This is important not least for our understanding of resistance to antibiotics. A research study from Uppsala University is now presenting a model of how bacteria can rapidly adapt to environmental changes through smart regulation of their gene expression.

'Designer sperm' inserts custom genes into offspring

Bethesda, MD—Get ready: The "new genetics" promises to change faulty genes of future generations by introducing new, functioning genes using "designer sperm." A new research report appearing online in The FASEB Journal, shows that introducing new genetic material via a viral vector into the sperm of mice leads to the presence and activity of those genes in the resulting embryos. This new genetic material is actually inherited, present and functioning through three generations of the mice tested.

A living desert underground

Hidden underneath the hilly grasslands studded with ocotillos and mesquite trees in southeastern Arizona lies a world shrouded in perpetual darkness: Kartchner Caverns, a limestone cave system renowned for its untouched cave formations, sculpted over millennia by groundwater dissolving the bedrock and carving out underground rooms, and passages that attract tourists from all over the world.