Body

Restoring surgeons' sense of touch during minimally invasive surgeries

A small, wireless capsule has been developed that can restore the sense of touch that surgeons are losing as they shift increasingly from open to minimally invasive surgery.

During open surgery, doctors rely on their sense of touch to identify the edges of hidden tumors and to locate hidden blood vessels and other anatomical structures: a procedure they call palpation. But this practice is not possible in minimally invasive surgery where surgeons work with small, specialized tools and miniature cameras that fit through small incisions in a patient's skin.

More than 40 percent of men over 75 undergo PSA screening despite national recommendations

GALVESTON, Texas – Many primary care doctors continue to administer the prostate-specific antigen test to even their oldest patients despite the fact that no medical organization recommends prostate cancer screening for men older than 75, according to new research from the University of Texas Medical Branch at Galveston.

Milk-maker hormone may help liver regenerate

Bethesda, Md. (Oct. 15, 2013)—The hormone prolactin is probably best known for its role in stimulating milk production in mothers after giving birth. But prolactin also has an important function in the liver. This organ has the highest number of prolactin receptors in the body, ports that allow this hormone to enter liver cells. There, prolactin signals these cells to multiply and new blood vessels to grow to fuel this organ's expansion.

Small bits of genetic material fight cancer's spread

A class of molecules called microRNAs may offer cancer patients two ways to combat their disease.

Researchers at Princeton University have found that microRNAs — small bits of genetic material capable of repressing the expression of certain genes — may serve as both therapeutic targets and predictors of metastasis, or a cancer's spread from its initial site to other parts of the body. The research was published in the journal Cancer Cell.

Towards a better understanding of inherited hearing loss

Montréal, October 15, 2013 – A team of researchers led by Dr. Michel Cayouette at the IRCM made an important discovery, published online yesterday by the scientific journal Developmental Cell, that could better explain some inherited forms of hearing loss in humans. The Montréal scientists identified a group of proteins crucial for shaping the cellular organ responsible for detecting sounds.

Willpower alone is not enough

"There are three components to motivation. The first is our conscious objectives and desires – for example, the aspiration for a highly paid role in a company in order to achieve a certain standard of living. We are also driven by unconscious, implicit motives. These are deeply rooted in our emotions and can include the desire to do things well, have an impact on and control over others, and engage in interpersonal relationships," explains Prof. Hugo Kehr from the Chair of Psychology at Technische Universität München (TUM).

Beyond antibiotics: 'PPMOs' offer new approach to bacterial infection, other diseases

CORVALLIS, Ore. – Researchers at Oregon State University and other institutions today announced the successful use of a new type of antibacterial agent called a PPMO, which appears to function as well or better than an antibiotic, but may be more precise and also solve problems with antibiotic resistance.

In animal studies, one form of PPMO showed significant control of two strains of Acinetobacter, a group of bacteria of global concern that has caused significant mortality among military personnel serving in Middle East combat.

How do consumers create markets? The case of the minimoto

Consumers have the power to do more than just respond to products that companies put on the market; they can actually change and develop new markets, according to a new study in the Journal of Consumer Research.

When time has a will of its own, powerless consumers don't have the will to wait

When consumers assign human characteristics to time, it makes it more difficult to wait for things (especially for people who don't feel powerful), according to a new study in the Journal of Consumer Research.

2013 Ocean Health Index shows food provision remains an area of great concern

(Santa Barbara, Calif.) –– In the 2013 Ocean Health Index (OHI) –– an annual assessment of ocean health lead by Ben Halpern, a research associate at UC Santa Barbara's National Center for Ecological Analysis and Synthesis (NCEAS) and professor at the Bren School of Environmental Science & Management –– scientists point to food provision as the factor that continues to require serious attention.

To live and learn: Making memories has to be a speedy business

This news release is available in French.

Iron supplementation can provide cognitive and physical benefits to anemic children

Giving daily iron supplements to anemic primary-school–aged children can have cognitive and physical benefits, according to a study published in CMAJ (Canadian Medical Association Journal).

JCI early table of contents for Oct. 15, 2013

Sound preconditioning prevents ototoxic drug-induced hearing loss in mice

Sound preconditioning prevents ototoxic drug-induced hearing loss in mice

The death of sensory hair cells in the ear results in irreversible hearing loss. Several classes of drugs, including aminoglycoside antibiotics and chemotherapy drugs are known to kill hair cells; however, in many cases the benefit of using the drug outweighs the potential for hearing loss. Previous research has shown that a class of proteins induced in response to cell stress, the heat shock proteins (HSPs), can protect against sensory hair cell death in response to ototoxic drugs.

Bone loss associated with increased production of ROS

Bone is constantly being broken down and remodeled. Osteoporosis results when bone resorption outpaces bone regeneration. Production of reactive oxygen species, a form of oxidative stress, has been predicted to promote bone loss, but a source of reactive oxygen is unknown.