Body

One-step tumor detection from dynamic morphology tracking on aptamer grafted surface

A team of researchers from the University of Texas at Arlington (UT-Arlington) in Texas, USA has demonstrated a novel cancer cell detection method based on real time cell behavior tracking on engineered surfaces. A synthetic RNA molecule is coated on chip surface to identify cancer cells. The otherwise "calm and quiet" cells on this surface show interesting dancing behavior when their membrane receptors are matched to the surface RNA molecules. The behavior is quantified using interesting image processing techniques.

Breast screening program effective in preventing some invasive cancers

Screening for and treatment of an early form of breast cancer has been found to prevent subsequent invasive cancer, according to research led by Queen Mary University of London (QMUL).

Ductal carcinoma in situ (DCIS) is described as a very early form of breast cancer, where cancer cells are present in milk ducts, but have not yet invaded the surrounding breast tissue. Around 4,800 people are diagnosed with DCIS in the UK each year and the main form of treatment is surgery followed by radiotherapy.

Microtubules act as cellular 'rheostat' to control insulin secretion

Microtubules -- cellular "highways" that deliver cargo to the cell membrane for secretion -- have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.

New way to make yeast hybrids may inspire new brews, biofuels

MADISON, Wis. - About 500 years ago, the accidental natural hybridization of Saccharomyces cerevisiae, the yeast responsible for things like ale, wine and bread, and a distant yeast cousin gave rise to lager beer.

Today, cold-brewed lager is the world's most consumed alcoholic beverage, fueling an industry with annual sales of more than $250 billion.

How cells are foiled by a herpesvirus family member in the virus-host arms race

MADISON, Wis. -- Not every virus wants to go viral -- at least, not immediately. Some want to slip in quietly. Hide. Wait for the perfect opportunity to attack.

In order to do so, the virus has to find a way to enter the cells of the human body without tripping the alarm, and stay there without notice. It's how HIV works, and also how viruses in the herpesvirus family, like human cytomegalovirus (HCMV), do their business.

Guided ultrasound plus nanoparticle chemotherapy cures tumors in mice

Thermal ablation with magnetic resonance-guided focused ultrasound surgery (MRgFUS) is a noninvasive technique for treating fibroids and cancer. New research from UC Davis shows that combining the technique with chemotherapy can allow complete destruction of tumors in mice.

Mystery of arsenic release into groundwater solved

Groundwater in South and Southeast Asia commonly contains concentrations of arsenic 20 to 100 times greater than the World Health Organization's recommended limit, resulting in more than 100 million people being poisoned by drinking arsenic-laced water in Bangladesh, Cambodia, India, Myanmar, Vietnam and China.

Montefiore-Einstein Investigators present research at 2015 American Society of Hematology Annual Meeting

December 4, 2015 -- (NEW YORK, NY) -- Investigators at Montefiore Einstein Center for Cancer Care (MECCC) , Albert Einstein College of Medicine's NCI-designated Albert Einstein Cancer Center and The Children's Hospital at Montefiore will present their research findings at the American Society of Hematology's (ASH) 57th Annual Meeting and Exposition.

What your father ate before you were born could influence your health

There is increasing evidence that parents' lifestyle and the environment they inhabit even long before they have children may influence the health of their offspring. A current study, led by researchers from the Novo Nordisk Foundation Center for Basic Metabolic Research, sheds light on how.

New leads in the struggle against a formidable leukemia

PORTLAND, Ore., Dec. 4, 2015 -- A coordinated push to decrypt a complex form of leukemia is delivering a trove of new drug candidates and treatment ideas, a dozen of which will be presented at the American Society of Hematology Annual Meeting in Orlando, Florida (Dec. 5-8).

Certain herpes viruses can infect human neurons

PHILADELPHIA - For years, researchers have noted a tantalizing link between some neurologic conditions and certain species of the herpes virus. In patients with Alzheimer's disease, multiple sclerosis, and cerebellar ataxia, among other neuropathies, the cerebrospinal fluid teems with Epstein-Barr virus (EBV). Yet, the nature of that link has remained unclear, as it has been assumed that EBV, as well as other viruses in the same sub-family, called gammaherpesviruses, cannot infect neurons.

Scientists investigated molecular processes for targeted dog cancer therapy

Almost every second dog above the age of ten years develops cancer. Modern tumor therapy combines surgery, radiation therapy and novel drug treatment options. While surgery and radiotherapy ensure adequate treatment for all animals at the University of Veterinary Medicine, Vienna, there is a growing gap in the treatment with modern therapeutics. The reason for this is that modern targeted agents are based on specific molecular genetics findings, which are not easy to transfer to dogs from humans or the preferred animal model in cancer research, the mouse.

Nursing community on path to transformation since IOM future of nursing report five years ago

WASHINGTON - Since the 2010 Institute of Medicine report The Future of Nursing: Leading Change, Advancing Health was issued, significant progress has been made related to many of the report's recommendations, which were geared toward helping nurses meet the heightened demand for health care and improving the nation's increasingly complex health system, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Jewish cuisine punching above its paunch

"In the late 30s, you could get a smoked meat sandwich for five cents," said Olivier Bauer, a professor at the University of Montreal's Faculty of Theology and Religious Studies. "Today, the sandwich is not cheap, but it has become a Montreal icon. The same is true for the bagel our city is famous for around the world." The researcher, who conducted a study on these two foods associated with Judaism, recently presented the results of his research at the international conference Food Heritage, Hybridity & Locality at Brown University, Rhode Island. His study is available on Papyrus.

Gene pair plays crucial role in colon cancer, Penn vet team shows

Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease's complex molecular underpinnings. In a new study out this month in the journal Cell Reports, researchers from the University of Pennsylvania describe two related genes in the Musashi family that are required for colon cancer to develop, and that may be useful targets for effective treatment.