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Scientists uncover mode of action of enzyme linked with several types of cancer

Scientists at the Institute for Research in Immunology and Cancer (IRIC) of the Université de Montréal have discovered a key mechanism used by cells to efficiently distribute chromosomes to new cells during cell multiplication. Published in the journal Molecular Cell, the study is the first to demonstrate that this mechanism relies on the polo kinase, an enzyme implicated in several cancers. Inhibiting this mechanism could be key to developing effective therapies to treat cancer.

Estrogen linked to lowered immunity in fish

Exposure to estrogen reduces production of immune-related proteins in fish. This suggests that certain compounds, known as endocrine disruptors, may make fish more susceptible to disease.

The research may provide new clues for why intersex fish, fish kills and fish lesions often occur together in the Shenandoah and Potomac rivers. The tests were conducted in a lab by scientists from the U.S. Geological Survey.

Simple drug treatment may prevent nicotine-induced SIDS: Study

A new study has identified a specific class of pharmaceutical drugs that could be effective in treating babies vulnerable to Sudden Infant Death Syndrome (SIDS), because their mothers smoked during pregnancy.

Cantabrian cornice has experienced seven cooling and warming phases over past 41,000 years

In 1996, an international team of scientists led by the University of Zaragoza (UNIZAR) started to carry out a paleontological survey in the cave of El Mirón. Since then they have focused on analysing the fossil remains of the bones and teeth of small vertebrates that lived in the Cantabrian region over the past 41,000 years, at the end of the Quaternary. The richness, great diversity and good conservation status of the fossils have enabled the researchers to carry out a paleoclimatic study, which has been published recently in the Journal of Archaeological Science.

Obesity does not worsen asthma, but may reduce response to medications

Being overweight or obese does not make asthma worse in patients with mild and moderate forms of the disease, according to a study by National Jewish Health researchers, although it may reduce the response to medications.

Ancient mammals shifted diets as climate changed

GAINESVILLE, Fla. --- A new University of Florida study shows mammals change their dietary niches based on climate-driven environmental changes, contradicting a common assumption that species maintain their niches despite global warming.

GEN reports on efforts to quickly develop swine flu vaccine

New Rochelle, NY, June 2, 2009—Scientists around the world are accelerating their efforts to develop a vaccine against the H1N1 influenza virus (Swine flu) as rapidly as possible, reports Genetic Engineering & Biotechnology News (GEN).

Texas AM researchers examine 'invading' bacteria in DNA

Call it advanced warfare on the most elemental of levels.

Researchers at Texas A&M University's Artie McFerrin Department of Chemical Engineering have discovered how certain types of bacteria integrate the DNA that they have captured from invading enemies into their own genetic makeup to increase their chances of survival.

Surgery in patients with RA is often 'too little, too late'

A new study published by the American Society of Plastic Surgeons reveals that one of the most common conditions caused by Rheumatoid Arthritis (RA) is best treated surgically, sooner rather than later. Patients with RA frequently experience a debilitating condition known as metacarpophalangeal joint disease, which is usually treated by replacing the knuckle joints with solid silicone joints.

NOTES advances suggest promising future for scarless surgery

CHICAGO, IL (June 2, 2009) – Researchers will present the latest advances in a technology that continues to change the face of gastroenterology and surgery, known as Natural Orifice Translumenal Endoscopic Surgery®, or NOTES®, today at Digestive Disease Week® 2009 (DDW®). NOTES eliminates the need for incisions and allows for less pain and scarring associated with traditional laparoscopic surgery along with a much faster recovery time for the patient.

NEJM study finds radiofrequency ablation can reverse Barrett's esophagus, reduce cancer risk

NEW YORK (May 29, 2009) -- Patients who have gastroesophageal reflux disease (GERD) for a prolonged period have an increased risk of developing Barrett's esophagus, a pre-cancerous condition where the tissue lining the esophagus becomes damaged by stomach acid and transformed into something like the inside of the stomach. New research finds that radiofrequency ablation -- an endoscopic procedure involving targeted thermal energy -- was very successful at restoring the esophagus and reducing risk for cancer.

Study: Indirect transmission can trigger influenza outbreaks in birds

Athens, Ga. – New data on the persistence of avian influenza viruses in the environment has allowed a team of University of Georgia researchers to create the first model that takes into account both direct and indirect transmission of the viruses among birds. The model, which is detailed in the early online edition of the journal Proceedings of the National Academy of Sciences, has the potential to shed new light on how outbreaks begin in wild bird populations.

Researchers engineer metabolic pathway in mice to prevent diet-induced obesity

In recent years, obesity has taken on epidemic proportions in developed nations, contributing significantly to major medical problems, early death and rising health care costs. According to Centers for Disease Control and Prevention estimates, at least a quarter of all American adults and more than 15 percent of children and adolescents are obese.

New arenavirus discovered as cause of hemorrhagic fever outbreak in South Africa and Zambia

May 28, 2009—Scientists at Columbia University's Mailman School of Public Health, the South African National Institute for Communicable Diseases of National Health Laboratory Service (NICD-NHLS), the U.S. Centers for Disease Control and Prevention, and Roche's 454 Life Sciences Corporation have discovered the new virus responsible for a highly fatal hemorrhagic fever outbreak in Zambia and South Africa in late 2008. It is the first new hemorrhagic fever-associated arenavirus from Africa identified in nearly four decades.

Weight management techniques reflect advances in the field

CHICAGO, IL (June 2, 2009) - Research presented today at Digestive Disease Week® 2009 (DDW®) demonstrates the tremendous progress being made in the field of weight management, including alternatives to gastric bypass surgery that are successful in terms of both weight loss and resolution of common co-morbidities including hypertension, diabetes, high cholesterol and other disabling conditions. DDW is the largest international gathering of physicians and researchers in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery.