Body

Key to evolutionary fitness: Cut the calories

Charles Darwin and his contemporaries postulated that food consumption in birds and mammals was limited by resource levels, that is, animals would eat as much as they could while food was plentiful and produce as many offspring as this would allow them to. However, recent research has shown that, even when food is abundant, energy intake reaches a limit, even in animals with high nutrient demands, such as lactating females.

Triggering muscle development -- a therapeutic cure for muscle wastage?

Scientists in the UK and Denmark have shown that if elderly men were given growth hormone and exercised their legs showed an appreciable muscle mass increase. Dr. Geoff Goldspink (Royal Free and University College Medical School, UK) says: "This raises the question: Can age-related loss of muscle strength and increased fragility be ameliorated by the therapeutic application of mechano growth factor (MGF)?". There is hope that MGF can also help sufferers of diseases such as muscular dystrophy, ALS, renal disease or cancer, for whom intensive exercise is not an option.

Mangrove-dependent animals globally threatened

More than 40 percent of a sample of amphibians, reptiles, mammals, and birds that are restricted to mangrove ecosystems are globally threatened with extinction, according to an assessment published in the July/August issue of BioScience. The study, by David A. Luther of the University of Maryland and Russell Greenberg of the Smithsonian Migratory Bird Center, was based on an extensive literature search and expert consultations.

Acid-reducing medicines may lead to dependency

Bethesda, MD (July 1, 2009) – Treatment with proton pump inhibitors (PPIs) for eight weeks induces acid-related symptoms like heartburn, acid regurgitation and dyspepsia once treatment is withdrawn in healthy individuals, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

The 'other' cruciate ligament: Newer treatments for PCL tears

ROSEMONT, Ill. While major advances have been made in the understanding of posterior cruciate ligament (PCL) anatomy and reconstruction, a literature review published in the July 2009 issue of the Journal of the American Academy of Orthopaedic Surgeons (JAAOS) finds that there must be continued advances in basic science research in order to determine the best course of treatment for those with PCL injuries.

Researchers find clear difference in quality, type of lung cancer info available in US and Japan

Aurora, COLO. -- A study published in the July 2009 issue of the Journal of Thoracic Oncology revealed that internet-based lung cancer information was of a higher quality in the United States (US) than in Japan. Dr. Yasushi Goto of the National Cancer Center Hospital in Tokyo and his team of researchers from both the US and Japan evaluated 150 Web sites and determined noticeable differences in the quality and type of information on lung cancer available over the internet in the two countries.

Genetic analysis reveals secrets of scorpion venom

Transcriptomic tests have uncovered the protein composition of venom from the Scorpiops jendeki scorpion. Researchers writing in the open access journal BMC Genomics have carried out the first ever venom analysis in this arachnid, and discovered nine novel poison molecules, never before seen in any scorpion species.

Biomarkers' ability to improve prediction of cardiovascular risk is modest

Measurement of known biomarkers of cardiovascular disease slightly improves the ability to predict future heart attack or stroke in healthy individuals, but not enough to change preventive therapies. The study led by investigators at Massachusetts General Hospital (MGH) and Lund University in Sweden appears in the July 1 Journal of the American Medical Association.

Findings of genetics study does not support causal association of C-reactive protein with CHD

This release is available in http://chinese..org/zh/emb_releases/2009-07/jaaj-fog062609.php">Chinese.

An analysis of the association between genetic variations of the inflammation biomarker C-reactive protein (CRP) with coronary heart disease failed to support a causal association, according to a study in the July 1 issue of JAMA.

Agent used in spinal surgery linked to higher complications rate, greater inpatient charges

Barriers hinder EMS workers from using best resuscitation practices

Local laws, insurance reimbursement and public misperceptions impede emergency medical services (EMS) workers from using best resuscitation practices, according to a study reported in Circulation: Cardiovascular Quality and Outcomes.

Less than half of local EMS systems follow national guidelines on transporting cardiac arrest patients and terminating unsuccessful out-of-hospital resuscitation efforts, said researchers who conducted three small focus groups at the 2008 National Association of Emergency Medical Services Physicians meeting in Jacksonville, Fla.

Current search for heart disease treatment may not be fruitful

A protein used by doctors to indicate a patient's risk of coronary heart disease may have drug developers barking up the wrong treatment tree, according to the authors of a study published today in the Journal of the American Medical Association (JAMA). Their research suggests that C-reactive protein, an enticing target for scientists working on new treatments for coronary heart disease, may not have a role in causing the disease, even though it is a predictive marker.

Study provides greater understanding of lyme disease-causing bacteria

Lyme disease in theU.S. is caused by the tick-borne bacteria Borrelia burgdorferi and usually begins with a skin lesion, after which the bacteria spread throughout the body to the nervous system, heart or joints. About 60 percent of untreated individuals develop arthritis, which affects the knees in particular. Lyme disease usually responds well to antibiotic therapy, but in rare cases arthritis can persist for months or years after treatment, a rare condition known as antibiotic-refractory Lyme arthritis.

Link found between history of periodontitis and cerebrovascular disease in men

Boston, Ma. – June 30, 2009 – The potential role of periodontitis, an inflammatory disease of the gums, in the risk of cardiovascular disease, particularly ischemic stroke, has received growing attention during the last decade. A new study is the first prospective cohort study to use clinical measures of periodontitis to evaluate the association between this disease and the risk of cerebrovascular disease. The study is published in Annals of Neurology, the official journal of the American Neurological Association

Risk of tuberculosis from arthritis medication examined

Treatment with anti-tumor necrosis factor (TNF) agents is recognized as a risk factor for tuberculosis (TB) in patients with immune-mediated inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, psoriatic arthritis and psoriasis. Most TB cases develop as a result of reactivation of a latent TB infection, and health authorities worldwide recommend screening for latent TB and treating patients before initiating anti-TNF treatment.