Body

In pro baseball pitchers, weak core linked to more missed days

COLUMBUS, Ohio – New research suggests that professional baseball pitchers with poor core stability are more likely to miss 30 or more days in a single season because of injury than are pitchers who have good control of muscles in their lower back and pelvis.

Throwing a loop to silence gene expression

All human cells contain essentially the same DNA sequence – their genetic information. How is it possible that shapes and functions of cells in the different parts of the body are so different? While every cell's DNA contains the same construction master plan, an additional regulatory layer exists that determines which of the many possible DNA programs are active. This mechanism involves modifications of genome-bound histone proteins or the DNA itself with small chemical groups (e.g. methylation).

What you eat and not just the number of calories, is a significant factor in diabetes risk

If you think losing weight is enough to prevent Type 2 diabetes, don't get your hopes up. A new research report in September 2014 issue of The FASEB Journal, suggests that you don't have to be overweight to develop Type 2 diabetes. This study compared genetically identical twins-one heavier and one leaner-and found that after eating a fast-food meal, the circulating metabolites, including those related to Type 2 diabetes, were found in both individuals at the same levels.

Are human breast milk microbiome 'neutral'?

Human breast milk is considered the most ideal source of nutrition for infants and it should have played a critical role in the evolution and civilizations of human beings. Unlike our intuitive perception, human milk contains a large number of bacterial species, including some opportunistic pathogens of humans. This phenomenon comes as no surprise to scientists and physicians.

Media coverage of a celebrity suicide can cause a large-scale copycat effect

Researchers who analyzed media coverage of the suicide of a national actress in South Korea and its impact on subsequent suicides found that the number of suicide-related articles surged around 80 times in the week after a suicide compared with the week prior.

Many articles (37.1%) violated several critical items on the World Health Organization suicide reporting guidelines, like containing a detailed suicide method. The investigators estimated that there were approximately 430 excess suicides during the 4 weeks after her death due to media coverage.

New method for non-invasive prostate cancer screening

WASHINGTON D.C., Sept. 2, 2014 – Cancer screening is a critical approach for preventing cancer deaths because cases caught early are often more treatable. But while there are already existing ways to screen for different types of cancer, there is a great need for even more safe, cheap and effective methods to save even more lives.

A handsome face could mean lower semen quality

Contrary to what one might expect, facial masculinity was negatively associated with semen quality in a recent Journal of Evolutionary Biology study. As increased levels of testosterone have been demonstrated to impair sperm production, this finding may indicate a trade-off between investments in secondary sexual signaling (i.e. facial masculinity) and fertility.

Interestingly, males estimated facial images generally more attractive than females did, suggesting that males may generally overestimate the attractiveness of other men to females.

Men who exercise less likely to wake up to urinate

MAYWOOD, Ill – Men who are physically active are at lower risk of nocturia (waking up at night to urinate), according to a study led by a Loyola University Chicago Stritch School of Medicine researcher.

The study by Kate Wolin, ScD, and colleagues is published online ahead of print in Medicine & Science in Sports & Exercise, the official journal of the American College of Sports Medicine.

Researchers uncover hidden infection route of major bacterial pathogen

Researchers at the University of Liverpool's Institute of Infection and Global Health have discovered the pattern of infection of the bacterium responsible for causing severe lung infections in people with cystic fibrosis.

Pseudomonas aeruginosa is usually harmless to humans, but in people with cystic fibrosis (CF) or who have weakened immune systems – such as those who have had an operation or treatment for cancer – it can cause infections that are resistant to antibiotics. In CF patients in particular, infections can be impossible to eradicate from the lungs.

Aging gracefully: Diving seabirds shed light on declines with age

Scientists who studied long-lived diving birds, which represent valuable models to examine aging in the wild, found that blood oxygen stores, resting metabolism and thyroid hormone levels all declined with age, although diving performance did not. Apparently, physiological changes do occur with age in long-lived species, but they may have no detectable effect on behavioral performance.

Could poor stomach absorption of drugs reduce autism medications' effectiveness?

Recent research has revealed that many children and adults with autism experience gastrointestinal symptoms and that such symptoms can impact the absorption and availability of medications.

Scientists devise a bar code for the bacteria that causes tuberculosis

Doctors and researchers will be able to easily identify different types of tuberculosis (TB) thanks to a new genetic barcode devised by scientists from the London School of Hygiene & Tropical Medicine.

The bacteria that cause the deadly respiratory disease have evolved into families of strains, or lineages, which may affect people differently.

To help identify the different origins and map how tuberculosis moves around the world, spreading from person to person through the air, the research team studied over 90,000 genetic mutations.

Computer simulations visualize ion flux

Ion channels are involved in many physiological and pathophysiological processes throughout the human body. A young team of researchers led by pharmacologist Anna Stary-Weinzinger from the Department of Pharmacology and Toxicology, University of Vienna investigated how ion flux through a voltage gated sodium ion channel works in detail. Since this process is incredibly fast (up to 100 million ions per seconds), computer simulations were performed to visualize sodium flux "in slow motion".

Understanding and improving the body's fight against pathogens

Scientists from A*STAR's Bioprocessing Technology Institute (BTI) have uncovered the crucial role of two signalling molecules, DOK3 and SHP1, in the development and production of plasma cells. These discoveries, published in two prestigious journals PNAS and Nature Communications, advance the understanding of plasma cells and the antibody response, and may lead to optimisation of vaccine development and improved treatment for patients with autoimmune diseases such as lupus and tumours such as multiple myeloma.

CNIC scientists find the key to the first cell differentiation in mammals

The CNIC scientists, working with investigators at the Hospital for Sick Children in Toronto, the Sloan-Kettering Institute and the University of Kumamoto, have identified a regulatory element implicated in the function of a gene that plays a crucial role in the first cell differentiation event, which gives rise to the embryonic and extraembryonic cell lineages. The discovery is published in Developmental Cell.