Body

New oral agents may prevent injury after radiation exposure

(Boston) – Researchers from Boston University School of Medicine (BUSM) and collaborators have discovered and analyzed several new compounds, collectively called the ''EUK-400 series,'' which could someday be used to prevent radiation-induced injuries to kidneys, lungs, skin, intestinal tract and brains of radiological terrorism victims. The findings, which appear in the June issue of the Journal of Biological Inorganic Chemistry, describe new agents which can be given orally in pill form, which would more expedient in an emergency situation.

A matter of density, not quantity

Exploring standards to advance microbial genomics

WALNUT CREEK, CA -- Microbes contribute to manifold human endeavors ranging from bioenergy to agriculture to medicine. Moreover, they make the Earth's biogeochemical cycles go round, a prerequisite for all life on the planet. Exceedingly numerous, they are also extremely diverse, encompassing most of Earth's total biodiversity. So it should come as no surprise to find that two-thirds of the nearly 5,000 genome projects reported in the Genomes OnLine Database (http://www.genomesonline.org) involve microbes.

Telomeres resemble DNA fragile sites

Telomeres, the repetitive sequences of DNA at the ends of linear chromosomes, have an important function: They protect vulnerable chromosome ends from molecular attack. Researchers at Rockefeller University now show that telomeres have their own weakness. They resemble unstable parts of the genome called fragile sites where DNA replication can stall and go awry. But what keeps our fragile telomeres from falling apart is a protein that ensures the smooth progression of DNA replication to the end of a chromosome.

New lab test offers better prediction of HIV microbicide safety

July 9, 2009 — (BRONX, NY) — Scientists at Albert Einstein College of Medicine of Yeshiva University have devised a laboratory test for predicting whether microbicides against HIV are safe for human use. The researchers have also discovered why several supposedly "safe" microbicides made women more susceptible to HIV infection. The study appears today in the online version of the Journal of Infectious Disease.

Preseason shoulder test may predict injury severity for baseball pitchers

KEYSTONE, CO (July 10, 2009) – Athletic injuries can derail any player's ability to compete, but for a baseball pitcher his shoulder strength and control is critical. A new study to be presented at the American Orthopaedic Society for Sports Medicine's (AOSSM) Annual Meeting in Keystone, Colorado, suggests that testing a pitcher's shoulder strength through a series of exercises during the preseason may help create a focused strength training program to prevent serious injury during the season.

Seals quickly respond to gain and loss of habitat under climate change

Southern Elephant seals responded rapidly to climate and habitat change and established a new breeding site thousands of kilometres from existing breeding grounds, according to new research.

Humans may give swine flu to pigs in new twist to pandemic

The strain of influenza, A/H1N1, that is currently pandemic in humans has been shown to be infectious to pigs and to spread rapidly in a trial pig population.

Dialysis safe for kidney patients' heart health

Dialysis treatments do not affect the heart health of kidney disease patients who have had a heart attack, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). Since cardiovascular disease is the most common cause of death in kidney disease patients, the findings are good news for individuals who need the treatments.

New theory gives more precise estimates of large-scale biodiversity

Ask biologists how many species live in a pond, a grassland, a mountain range or on the entire planet, and the answers get increasingly vague. Hence the wide range of estimates for the planet's biodiversity, predicted to be between 2 million and 50 million species.

A new way of estimating species richness reported this month in the journal Ecology Letters by University of California, Berkeley, ecologist John Harte and colleagues, will make such estimates more precise for habitats of all sizes and types, from deserts to tropical rainforests.

Elevated insulin linked to increased breast cancer risk

July 9, 2009 - (BRONX, NY) - Elevated insulin levels in the blood appear to raise the risk of breast cancer in postmenopausal women, according to researchers at Albert Einstein College of Medicine of Yeshiva University. Their findings are published in the online version of the International Journal of Cancer.

Finnish study identifies factors that increase death in stroke patients ages 15 to 49

Heavy drinking, being 45 to 49 years old, type 1 diabetes or having a preceding infection are associated with more than twice the risk of death in stroke patients 15 to 49 years old, according to a Finnish study.

Furthermore, heart failure was associated with seven times the risk of death and active cancer malignancy with 16 times the risk of death in stroke patients.

2,000-year-old statue of an athlete sheds light on corrosion and other modern challenges

The restoration of a 2,000-year-old bronze sculpture of the famed ancient Greek athlete Apoxyomenos may help modern scientists understand how to prevent metal corrosion, discover the safest ways to permanently store nuclear waste, and understand other perplexing problems. That's the conclusion of a new study on the so-called "biomineralization" of Apoxyomenos appearing in the current issue of ACS' Crystal Growth & Design, a bi-monthly journal. Best known as "The Scraper," the statue depicts an athlete scraping sweat and dust from his body with a small curved instrument.

Mystery: How can we maintain human embryonic stem cells in the lab?

DALLAS – July 9, 2009 – A new study says scientists at UT Southwestern Medical Center have discovered why mouse embryonic ste, (ES) cells can be easily grown in a laboratory while other mammalian ES cells are difficult, if not impossible, to maintain.

If the findings in mice can be applied to other animals, scientists could have an entirely new palette of research tools to work with, said Dr. Steven McKnight, chairman of biochemistry at UT Southwestern and senior author of the study appearing in the July 9 issue of Science Express.

Periodontal disease and cardiovascular disease inflammatory connection explained

BALTIMORE (July 9, 2009) – Is your head where your heart is? It may be now. A strong connection between periodontal disease and cardiovascular disease (CVD) has been suggested in recent clinical studies. As many as 75 percent of adults in the United States have been affected by periodontal disease and an estimated 80.7 million adults (1 out of every 3) have been a victim of CVD in 2006 according to the American Heart Association. From the 80.7 million adults in the United States, 38.2 million are less than 60 years of age, which is almost 50 percent. According to Marvin J.