Body

Molecular imaging technology used in gastric cancer

Modern cancer care is critically dependent on imaging technologies, which are used to detect early tumors and guide their therapy or surgery. Molecular imaging technologies provide information about the functional or metabolic characteristics of malignancies, tumor stage and therapeutical response, and tumor recurrence; whereas conventional imaging technologies predominantly assess the tumor's anatomical or morphologic features including its size, density, shape, etc.

Simple, inexpensive and objective tools for the assessment of mucosal inflammation: fecal markers

UC and CD, the two major forms of IBD are chronic, idiopathic inflammatory conditions of the gut with a typically relapsing and remitting course. A prominent feature in mucosal biopsies from patients with active IBD is infiltration by neutrophil granulocytes. Moreover, the number of eosinophil granulocytes is also increased in IBD. Upon activation, neutrophils release Calprotectin and MPO, two major neutrophil proteins, while eosinophils release the protein, EPX.

What is the clinical features of primary aortoenteric fistula?

PAEF is a rare but often life-threatening cause of massive gastrointestinal bleeding. PAEFs have a mortality rate of nearly 100% in the absence of surgical intervention, and in most case, the diagnosis is not established preoperatively. This report presents one such case wherein the cause of death was PAEF-induced massive gastrointestinal bleeding that occurred after discharge of the patient from the hospital. Few previous reports on PAEF provide both the clinical course, including gastrointestinal endoscopic findings, and detailed autopsy findings.

Chronic infection most common cause of adult tonsillectomy

Chicago, IL – Efforts to fill in holes in data regarding the primary causes of tonsillectomy in adults have determined that chronic infection is the most common reason for the procedure, according to new research presented at the 2008 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in Chicago, IL.

Great bustards to be released on Salisbury Plain

Researchers at the University of Bath and conservationists from the Great Bustard Group will be releasing 19 birds on Salisbury Plain on Thursday 25 September as part of an ongoing reintroduction project in the UK.

A prospective clinical diagnosis marker for digestive system cancer: nm23H1

Growing evidence suggests that accumulation of multiple alterations such as activation of proto-oncogenes and inactivation of tumor suppressor genes is responsible for the development and progression of digestive system cancer. Genetic instability of oncogenes such as microsatellite instability (MSI) and loss of heterozygosity (LOH) is probably associated with mutations in genes responsible for tumor-genesis, and they play important roles in tumor clinical pathology.

Variety of foods -- the key for child nutrition

New research shows that most children have a diet that contains enough essential vitamins and minerals.

Analysis of the Government's own survey of children's diets and nutritional status has shown that the average child gets the recommended level of most vitamins and minerals, even though they consume more added sugars than recommended.

NTDs burden in Latin America and the Caribbean may exceed that of HIV/AIDS, TB and malaria

According to a new analysis published September 24th in the open-access journal PLoS Neglected Tropical Diseases, "The Neglected Tropical Diseases of Latin America and the Caribbean: A Review of Disease Burden and Distribution and a Roadmap for Control And Elimination,", neglected tropical diseases (NTDs) as a group may have surpassed HIV/AIDS, tuberculosis and malaria as the most prevalent infectious diseases in Latin America and the Caribbean. The analysis found that NTDs are the most common infections of approximately 200 million of the poorest people in the region.

Prolonged effects of a warming anomaly on grasslands

Professors Yiqi Luo, Linda Wallace and Rebecca Sherry in the Department of Botany and Microbiology coauthored a paper with colleagues Jay Arnone and Paul Verburge at the Desert Research Institute; Dale Johnson from the University of Nevada at Reno; David Chimel from the National Center for Atmospheric Research; and others to report their findings on the long-term effects of warming anomaly on grassland productivity and ecosystem carbon cycling.

Geisinger study: Increasing health care value improves health care quality

DANVILLE, PA. – Finding better ways to deliver healthcare to patients is key to ensuring that Medicare is able to meet the needs of the nation's baby boomers according to a new paper by Geisinger Health System published in Health Affairs.

Swiss Institute of Bioinformatics announces major breakthrough

Speaking at the 10th anniversary conference of the Swiss Institute ofBioinformatics in Berne, Switzerland, its director Professor Ron Appeldescribed his institute as a "Swiss success story". He said that he wasproud that as pioneers at the heart of science one of the SIB's 25 workinggroups was today able to announce the completion of the annotation ofhuman proteins.

Professor Amos Bairoch, head of the SIB's Swiss-Prot group said: "If humanDNA is the script of life, proteins are its actors, its living embodiment."

Racial disparities decline for cancer in Missouri

Sept. 23, 2008 -- Cancer death rates in the United States are highest among African Americans, but a new report shows that in Missouri the disparity in cancer incidence and death between African Americans and whites is declining. As a result, cancer incidence (the rate of newly diagnosed cases) between the races is equal, although the death rate will probably remain higher for African Americans for some time.

Worm genome offers clues to evolution of parasitism

The genome of a humble worm that dines on the microbial organisms covering the carcasses of dead beetles may provide clues to the evolution of parasitic worms, including those that infect humans, say scientists at Washington University School of Medicine in St. Louis and the Max-Planck Institute for Developmental Biology in Germany.

In a paper published in the current issue of Nature Genetics, the researchers reported finding some surprises as they have decoded the genome of the worm, a tiny nematode called Pristionchus pacificus.

OHSU Cancer Institute researchers study breathing during radiation

PORTLAND, Ore. – Oregon Health & Science University researchers have determined exactly how much breathing affects prostate movement during radiation treatment.

The results of this research are being presented from 5 p.m. to 6:30 p.m. today at the 50th annual American Society for Therapeutic Radiology and Oncology in Boston.

Caffeine experts at Johns Hopkins call for warning labels for energy drinks

Johns Hopkins scientists who have spent decades researching the effects of caffeine report that a slew of caffeinated energy drinks now on the market should carry prominent labels that note caffeine doses and warn of potential health risks for consumers.