Body

EuroPCR 2014 session defines future horizons for renal denervation

23 May 2014, Paris, France: During EuroPCR 2014, Felix Mahfoud, University Hospital in Homburg, Germany, and Konstantinos Tsioufis, University of Athens, Greece, reflected on the potential future role of modulation of the sympathetic nervous system in patients with difficult-to-control hypertension.

In the context of the SYMPLICITY-HTN-3 clinical trial results, questions were raised about the extent of the procedure's efficacy although the randomised, controlled trial confirmed the safety of renal denervation.

New biodiversity study throws out controversial scientific theory

Researchers have today released ground-breaking findings that dismiss the 'Neutral Theory of Biodiversity'. The theory has dominated biodiversity research for the past decade, and been advocated as a tool for conservation and management efforts.

A novel disease-preventing antioxidant pathway

Interested in antioxidants? They protect us against aging and cancer. It's one of the reasons we like our green tea and even our broccoli. But there is a new kid on the antioxidant block - uric acid. But wait, you're thinking, doesn't uric acid cause gout? A team in Singapore has recently showed that uric acid is a major intracellular antioxidant, possibly even more important than the antioxidants we try to eat. They also discovered how uric acid helps to prevent aging and disease and how it helps in the treatment of cancer.

Immunologists discover immune system precursor cells that fight infection

The innate immune system recognizes infectious agents such as viruses and bacteria. A group of lymphocytes known as "innate lymphoid cells" or ILCs plays a central role in the defense of the human body against infective agents. Professor Andreas Diefenbach of the Research Center Immunology at the Mainz University Medical Center, working in collaboration with scientists at the University of Freiburg, has discovered previously unidentified ILCs that are able to protect epithelial surfaces, such as those of the intestinal mucosa, against infection.

HIV can cut and paste in the human genome

For the first time researchers have succeeded in altering HIV virus particles so that they can simultaneously, as it were, 'cut and paste' in our genome via biological processes. Developed at the Department of Biomedicine at Aarhus University, the technology makes it possible to repair genomes in a new way. It also offers good perspectives for individual treatment of both hereditary diseases and certain viral infections:

Stanford researchers discover immune system's rules of engagement

A study led by researchers at Stanford's School of Medicine reveals how T cells, the immune system's foot soldiers, respond to an enormous number of potential health threats.

X-ray studies at the Department of Energy's SLAC National Accelerator Laboratory, combined with Stanford biological studies and computational analysis, revealed remarkable similarities in the structure of binding sites, which allow a given T cell to recognize many different invaders that provoke an immune response.

Climate change accelerates hybridization between native and invasive species of trout

BOZEMAN, Mont. – Scientists have discovered that the rapid spread of hybridization between a native species and an invasive species of trout in the wild is strongly linked to changes in climate.

In the study, stream temperature warming over the past several decades and decreases in spring flow over the same time period contributed to the spread of hybridization between native westslope cutthroat trout and introduced rainbow trout – the world's most widely introduced invasive fish species –across the Flathead River system in Montana and British Columbia, Canada.

Hot flashes/night sweats solutions: Estrogen therapy vs. venlafaxine

BOSTON, MA – A new research study from Brigham and Women's Hospital (BWH) that compares low-dose oral estrogen and low-dose non-hormonal venlafaxine hydrochloride extended release (XR) to placebo were both found effective in reducing the number of hot flashes and night sweats reported by menopausal women. The study is the first clinical trial to simultaneously evaluate estrogen therapy (ET), known as the "gold standard" treatment for hot flashes and night sweats, and a non-hormonal treatment, venlafaxine, a first-line treatment in women who are unwilling or unable to use ET.

New perspectives to the design of molecular cages

Researchers from the University of Jyväskylä report a new method of building molecular cages. The method involves the exploitation of intermolecular steric effects to control the outcome of a self-assembly reaction.

Molecules do the triple twist

An international research team led by Academy Professor Kari Rissanen of the University of Jyväskylä (Finland) and Professor Rainer Herges of the University of Kiel (Germany) has managed to make a triple-Möbius annulene, the most twisted fully conjugated molecule to date, as reported in Nature Chemistry (DOI:10.1038/nchem.1955, published online 25 May 2014).

Insights into genetics of cleft lip

Scientists at the European Molecular Biology Laboratory (EMBL) in Heidelberg, have identified how a specific stretch of DNA controls far-off genes to influence the formation of the face. The study, published today in Nature Genetics, helps understand the genetic causes of cleft lip and cleft palate, which are among the most common congenital malformations in humans.

Clinical trial reaffirms diet beverages play positive role in weight loss

May 27, 2014 – A groundbreaking new study published today in Obesity, the journal of The Obesity Society, confirms definitively that drinking diet beverages helps people lose weight.

Africa's longest-known terrestrial wildlife migration discovered

WASHINGTON, DC - Researchers have documented the longest-known terrestrial migration of wildlife in Africa – up to several thousand zebra covering a distance of 500km (more than 300 miles) – according to World Wildlife Fund (WWF).

An area's level of poverty or wealth may affect the distribution of cancer types

A new analysis has found that certain cancers are more concentrated in areas with high poverty, while other cancers arise more often in wealthy regions. Also, areas with higher poverty had lower cancer incidence and higher mortality than areas with lower poverty. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study's findings demonstrate the importance of including measures of socioeconomic status in national cancer surveillance efforts.

E-cigarettes: Not a healthy alternative to smoking

ARLINGTON HEIGHTS, Ill. (May 27, 2014) – Caveat emptor – or "buyer beware" holds true when it comes to the unknown health effects of e-cigarettes. An article in the June issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), examines risks, including the ongoing dependence on nicotine and the dual use of e-cigarettes and regular cigarettes.