In a first of its kind discovery, University of Minnesota researchers have identified the "master gene" behind blood vessel development. Better understanding of how this gene operates in the early stages of development may help researchers find better treatments for heart disease and cancer.
Using genetically engineered mice, researchers with the University of Minnesota Medical School's Lillehei Heart Institute were able to identify a protein, Nkx2-5, which activates a certain gene, and in turn, determines the fate of a group of cells in a developing embryo.