Body

Why are the faces of primates so dramatically different from one another?

UCLA biologists working as "evolutionary detectives" studied the faces of 129 adult male primates from Central and South America, and they offer some answers in research published today, Jan. 11, in the early online edition of the journal Proceedings of the Royal Society B. The faces they studied evolved over at least 24 million years, they report.

Interferon-stimulated gene 15 (ISG15), a ubiquitin like protein, is highly elevated in a variety of cancers including breast cancer. How the elevated ISG15 pathway contributes to tumorigenic phenotypes remains unclear and is the subject of a study published in the January 2012 issue of Experimental Biology and Medicine. Dr.

SEATTLE – Among overweight and obese adults, a diet rich in slowly digested carbohydrates, such as whole grains, legumes and other high-fiber foods, significantly reduces markers of inflammation associated with chronic disease, according to a new study by Fred Hutchinson Cancer Research Center. Such a "low-glycemic-load" diet, which does not cause blood-glucose levels to spike, also increases a hormone that helps regulate the metabolism of fat and sugar. These findings are published online ahead of the February print issue of the Journal of Nutrition.

BOSTON -- A team led by researchers at Dana-Farber Cancer Institute has isolated a natural hormone from muscle cells that triggers some of the key health benefits of exercise. They say the protein, which serves as a chemical messenger, is a highly promising candidate for development as a novel treatment for diabetes, obesity and perhaps other disorders, including cancer.

The chemotherapy drugs required to push a common form of adult leukemia into remission may contribute to DNA damage that can lead to a relapse of the disease in some patients, findings of a new study suggest.

The research, by a team of physicians and scientists at Washington University School of Medicine in St. Louis, is published Jan. 11 in the advance online edition of Nature.

New findings from the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) have helped identify the mechanism that makes the childhood eye tumor retinoblastoma so aggressive. The discovery explains why the tumor develops so rapidly while other cancers can take years or even decades to form.

Researchers have discovered that a subtype of leukemia characterized by a poor prognosis is fueled by mutations in pathways distinctly different from a seemingly similar leukemia associated with a much better outcome. The findings from the St. Jude Children's Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) highlight a possible new strategy for treating patients with this more aggressive cancer.

Santa Barbara, CA – Every year, a group of anti-whaling nonprofit organizations that includes Greenpeace, Sea Shepherd, and the World Wildlife Fund spend, by conservative estimates, some $25 million on a variety of activities intended to end commercial whaling.

And every year, commercial whaling not only continues, but grows.

A new clinical Standard Reference Material (SRM) from the National Institute of Standards and Technology (NIST) will help health care professionals more accurately diagnose and treat cytomegalovirus (CMV), a common pathogen that is particularly dangerous for infants and persons with weakened immune systems.

ATLANTA –January 11, 2012– Updated guidelines on nutrition and physical activity for cancer prevention from the American Cancer Society stress the importance of creating social and physical environments that support healthy behaviors. The report includes updated recommendations for individual choices regarding diet and physical activity patterns, but emphasizes that those choices occur within a community context that can either help or hinder healthy behaviors.

Troy, N.Y. – A scientist at Rensselaer Polytechnic Institute and an anthropologist from the University at Albany teamed up to use ultra-modern chemical analysis technology at Rensselaer to analyze ancient Mayan pottery for proof of tobacco use in the ancient culture. Dmitri Zagorevski, director of the Proteomics Core in the Center for Biotechnology and Interdisciplinary Studies (CBIS) at Rensselaer, and Jennifer Loughmiller-Newman, a doctoral candidate at the University at Albany, have discovered the first physical evidence of tobacco in a Mayan container.

Why do heavy coffee drinkers have a lower risk of developing Type 2 diabetes, a disease on the increase around the world that can lead to serious health problems? Scientists are offering a new solution to that long-standing mystery in a report in ACS' Journal of Agricultural & Food Chemistry.

Nobel laureate poet Rabindranath Tagore once wrote, "Let your life lightly dance on the edges of time like dew on the tip of a leaf." Now, a new study is finally offering an explanation for why small dew drops do as Tagore advised and form on the tips, rather than the flat surfaces, of leaves. It appears in ACS' journal Langmuir.

BOSTON (January 11, 2012) — New research demonstrates that previous models used to examine cancer may not be complex enough to accurately mimic the true cancer environment. Using oral cancer cells in a three-dimensional model of lab-made tissue that mimics the lining of the oral cavity, the researchers found that the tissue surrounding cancer cells can epigenetically mediate, or temporarily trigger, the expression or suppression of a cell adhesion protein associated with the progression of cancer.

(Boston) – A review article by researchers at Boston University School of Medicine (BUSM) debunks the widely-believed concept that hypertension, or high blood pressure, is the result of excess salt causing an increased blood volume, exerting extra pressure on the arteries. Published online in the Journal of Hypertension, the study demonstrates that excess salt stimulates the sympathetic nervous system to produce adrenalin, causing artery constriction and hypertension.