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Lessons from tens of millions of years ago are pointing to new ways to save and protect today's coral reefs and their myriad of beautiful and many-hued fishes at a time of huge change in the Earth's systems.

The complex relationship we see today between fishes and corals developed relatively recently in geological terms – and is a major factor in shielding reef species from extinction, says Professor David Bellwood of the ARC Centre of Excellence for Coral Reef Studies and James Cook University.

Quality of life in younger patients treated for breast cancer is seriously compromised and these women suffer from severe psychological distress, infertility, premature menopause, a decrease in physical activity and weight gain, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

The same mechanism that stabilises the DNA in the cell nucleus is also important for the structure and function of vertebrate muscle cells. This has been established by RUB-researchers led by Prof. Dr. Wolfgang Linke (Institute of Physiology) in cooperation with American and German colleagues. An enzyme attaches a methyl group to the protein Hsp90, which then forms a complex with the muscle protein titin. When the researchers disrupted this protein network through genetic manipulation in zebrafish the muscle structure partly disintegrated.

An international team of researchers has discovered 13 new regions of the genome associated with the timing of menopause. These genes shed light on the biological pathways involved in reproductive lifespan and will provide insights into conditions connected to menopause, such as breast cancer and heart disease.

A new suite of malaria maps has revealed in unprecedented detail the current global pattern of the disease, allowing researchers to see how malaria has changed over a number of years.

The survival of the endangered snow leopard is looking promising thanks to Monash University scientists who have, for the first time, produced embryonic stem-like cells from the tissue of an adult leopard.

Never before have induced pluripotent stem (iPS) cells, which share many of the useful properties of embryonic stem cells, been generated from a member of the cat family. The breakthrough raises the possibility of cryopreservation of genetic material for future cloning and other assisted reproduction techniques.

A new analysis has found that a substantial number of lung and colorectal cancer patients continue to smoke after being diagnosed. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides valuable information on which cancer patients might need help to quit smoking.

The blind Mexican cavefish (Astyanax mexicanus) have not only lost their sight but have adapted to perpetual darkness by also losing their pigment (albinism) and having altered sleep patterns. New research published in BioMed Central's open access journal BMC Evolutionary Biology shows that the cavefish are an example of convergent evolution, with several populations repeatedly, and independently, losing their sight and pigmentation.

Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells

Luteolin is a flavonoid commonly found in fruit and vegetables. This compound has been shown in laboratory conditions to have anti-inflammatory, anti-oxidant and anti-cancer properties but results from epidemiological studies have been less certain. New research published in BioMed Central's open access journal BMC Gastroenterology shows that luteolin is able to inhibit the activity of cell signaling pathways (IGF and PI3K) important for the growth of cancer in colon cancer cells.

SAN FRANCISCO, CA—January 22, 2012—Scientists at the Gladstone Institutes have identified a finely tuned mechanism by which fetal heart muscle develops into a healthy and fully formed beating heart—offering new insight into the genetic causes of congenital heart disease and opening the door to one day developing therapies to fight this chronic and potentially fatal disorder.

LA JOLLA, CA – January 22, 2012 – Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But a team led by scientists from The Scripps Research Institute, using a new approach known as metabolomics, has now discovered a major clue: dimethylsphingosine (DMS), a small-molecule byproduct of cellular membranes in the nervous system.

Under a year since a huge tsunami inundated paddy fields in Japan with salty sludge, scientists are near to developing locally-adapted, salt-tolerant rice.

Following a Japan-UK research collaboration, a new method for marker assisted breeding is being used to slash the time it takes to isolate new traits such as salt tolerance. Details of the new method, called MutMap, will be published in Nature Biotechnology on Sunday so they can be used by scientists and breeders worldwide to dramatically accelerate crop breeding.

DURHAM, N.C. and SINGAPORE – Researchers at Duke University Medical Center have created synthetic nanoparticles that target lymph nodes and greatly boost vaccine responses, said lead author Ashley St. John, Ph.D., a researcher at Duke-NUS Graduate Medical School.

The paper was published online in the journal Nature Materials on Jan. 22.

Doctors and researchers of Hospital del Mar and its research institute, the IMIM, have lead a study describing a new pharmacological resistance to cancer. This new mechanism is a mutation in an oncogene called EGFR (epidermal growth factor receptor) causing resistance to treatment using a drug called cetuximab, a monoclonal antibody which specifically attacks the EGFR.

HOUSTON - Chronic inflammation combines with DNA methylation, a process that shuts down cancer-fighting genes, to promote development of colorectal cancer, scientists at The University of Texas MD Anderson Cancer Center report today in the advance online publication of the journal Nature Medicine.

The team's connection of these two separate influences eventually may lead to better combination therapies for treating and preventing colorectal cancer.