Body

Decoding the molecular machine behind E. coli and cholera

Scientists from Queen Mary, University of London have discovered the workings behind some of the bacteria that kill hundreds of thousands every year, possibly paving the way for new antibiotics that could treat infections more effectively.

With antibiotic resistance on the rise in strains of pathogenic bacteria, innovative strategies are needed to discover ways of treating bacterial infections in both humans and in agriculture.

New avenue for treating colon cancer

RIVERSIDE, Calif. — An international research team led by cell biologists at the University of California, Riverside has uncovered a new insight into colon cancer, the third leading cause of cancer-related deaths in the United States. The research provides potential new avenues for diagnosing and treating the disease.

An economic analysis of Emerald Ash Borer management options

The emerald ash borer, Agrilus planipennis (Fairmaire), an invasive insect from Asia which was first found in the U.S. in the 1990s, has since spread to 15 states and is responsible for the deaths of millions of ash trees. This insect has the potentionl to kill billions more trees and to do several billions of dollars worth of damage.

New method makes culture of complex tissue possible in any lab

Scientists at the University of California, San Diego have developed a new method for making scaffolds for culturing tissue in three-dimensional arrangements that mimic those in the body. This advance, published online in the journal Advanced Materials, allows the production of tissue culture scaffolds containing multiple structurally and chemically distinct layers using common laboratory reagents and materials.

Study indicates that cesarean delivery may not be more protective for small, premature newborns

DALLAS (Feb. 9, 2012) — In a study to be presented today at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting ™, in Dallas, Texas, researchers will report findings that suggest that delivery by cesarean section may not be protective compared to vaginal deliveries for babies who are small for their gestational age (those weighing less than the 10th percentile at birth based on national growth curves) born more than six weeks before their due date.

New prenatal genetic test is much more powerful at detecting fetal abnormalities

NEW YORK -- A nationwide, federally funded study has found that testing a developing fetus' DNA through chromosomal microarray (CMA) provides more information about potential disorders than does the standard method of prenatal testing, which is to visually examine the chromosomes (karyotyping). The results of the 4,000-plus-participant clinical study are being presented at the 32nd annual meeting of the Society for Maternal-Fetal Medicine in Dallas on Feb. 9, 2012. The study was recently published in the American Journal of Obstetrics & Gynecology.

Scripps research scientists identify most lethal known species of prion protein

JUPITER, FL -- Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in "mad cow" disease, but is at least 10 times more lethal than larger prion species.This toxic single molecule or "monomer" challenges the prevailing concept that neuronal damage is linked to the toxicity of prion protein aggregates called "oligomers."

The study was published this week in an advance, online edition of the journal Proceedings of the National Academy of Sciences.

Hydrogen from acidic water

A technique for creating a new molecule that structurally and chemically replicates the active part of the widely used industrial catalyst molybdenite has been developed by researchers with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab). This technique holds promise for the creation of catalytic materials that can serve as effective low-cost alternatives to platinum for generating hydrogen gas from water that is acidic.

Ultraviolet protection molecule in plants yields its secrets to Scripps research team

LA JOLLA, CA – Lying around in the sun all day is hazardous not just for humans but also for plants, which have no means of escape. Ultraviolet (UV) radiation from the sun can damage proteins and DNA inside cells, leading to poor growth and even death (as well as carcinogenesis in humans). But plants have evolved some powerful adaptive defenses, including a complex array of protective responses orchestrated by a UV-sensing protein molecule known as UVR8.

New research shows C-section not always best for babies

DALLAS, Feb. 9, 2012 – The widely-held assumption that a cesarean delivery has no health risks for the baby is being challenged today by new research that found the procedure did not help some preterm babies who were small for gestational age, and may even have contributed to their breathing problems.

Genetic risks for type 2 diabetes span multiple ethnicities

A recent large and comprehensive analysis of 50,000 genetic variants across 2,000 genes linked to cardiovascular and metabolic function has identified four genes associated with type 2 diabetes (T2D) and six independent disease-associated variants at previously known loci. The findings, which provide valuable insight into the genetic risk for T2D across multiple ethnicities, add to the growing list of genetic variants that affect the risk of developing T2D and could pave the way for identification of valuable drug targets.

Ocean warming causes elephant seals to dive deeper

Global warming is having an effect on the dive behaviour and search for food of southern elephant seals. Researchers from the Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Association cooperating in a joint study with biologists and oceanographers from the Universities of Pretoria and Cape Town have discovered that the seals dive deeper for food when in warmer water. The scientists attribute this behaviour to the migration of prey to greater depths and now wish to check this theory using a new sensor which registers the feeding of the animals below water.

Training in muscle power improves the functional capacity and quality of life of elderly people

Twelve weeks of training geared towards improving muscular power in older people are highly effective for improving their functional capacity and quality of life, as shown by the studies carried out by the "Biomechanics and Physiology of Movement" research group at the Public University of Navarre led by Professor Mikel Izquierdo-Redin.

Largest-ever gene study of Type 2 diabetes finds variants across many ethnic groups

The largest genetics study to date of type 2 diabetes (T2D) has identified new gene variants associated with risk for the common metabolic disease. An international scientific consortium, studying multiethnic populations, uncovered genes that may point to biological targets for developing more effective drugs for T2D.

Multiple genes and environmental factors interact with T2D, which affects nearly 300 million people worldwide. The majority of the gene variants remain undiscovered.

Sustainable land use strategies to support bioenergy described in Industrial Biotechnology journal

New Rochelle, NY, February 9, 2012—Applying 21st century tools and technologies to manage land use, maximize biomass production, and increase the efficiency of processes for extracting energy from renewable resources will enable the biofuels industry to overcome current challenges in bioenergy production, according to a comprehensive review article published in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc. (http://www.liebertpub.com).