Body

GW researchers reveal digital transcriptome of breast cancer

GW Cancer Research Team in the Department of Biochemistry and Molecular Biology, in the School of Medicine and Health Sciences, published a study that is the first of its kind to use mRNA sequencing to look at the expression of genome, at a unprecedented resolution at the current time, in three types of breast cancer. The study titled, "Transcriptomic landscape of breast cancer through mRNA sequencing," is published in the Feb. 14 edition of the journal, Scientific Reports, a new open access Nature journal for large volume data.

Crippleware: How do consumers react when companies disable product features?

Consumers dislike it when manufacturers remove or degrade features in existing models—even though it's a common practice, according to a new study in the Journal of Consumer Research.

"Product versioning—the manufacturing strategy of deliberate subtraction of functionality from a product—is typically achieved when a firm starts with an existing product and produces a lower-quality or reduced-feature configuration," write authors Andrew Gershoff (University of Texas at Austin), Ran Kivetz (Columbia University), and Anat Keinan (Harvard University).

What does 'happiness' mean to consumers? Does age matter?

Happiness means different things to different consumers, depending on whether they're focused on the future or the present, according to a new study in the Journal of Consumer Research.

Analyzing the causes of obesity in the Romani ethnic group

Esther Rebato is a well-known figure in the field of Physical Anthropology. She not only holds the prestigious Alex Hrdlièka academic medal of the Czech Republic, but she is also the Chair of the Spanish Association of Physical Anthropology. This lecturer at the Department of Genetics, Physical Anthropology and Animal Physiology of the University of the Basque Country (UPV/EHU) has carried out numerous pieces of work into nutritional habits, life quality and other associated aspects.

Bumblebees get by with a little help from their honeybee rivals

Bumblebees can use cues from their rivals the honeybees to learn where the best food resources are, according to new research from Queen Mary, University of London.

Writing in the journal PLoS ONE, the team from Queen Mary's School of Biological and Chemical Sciences explain how they trained a colony of bumblebees (Bombus terrestris) to use cues provided by a different species, the honeybee (Apis mellifera), as well as cues provided by fellow bumblebees to locate food resources on artificial flowers.

From prediction to reality -- a new class of bulk insulator but surface conductor material

As a result of a joint intensive work of several groups from five different countries, including Basque Country, a new wide class of topological insulators materials that are insulators in the bulk but conductors at the surface with technologically very promising properties has been discovered.

Shear stiffness and friction mechanics of single-layer graphene measured for the first time

Researchers from the University of Bristol have measured and identified for the first time the stress and strain shear modulus and internal friction of graphene sheets. Graphene is a material that has many potential groundbreaking uses in the electronics and composites industry.

The research, in collaboration with the US Office of Naval Research, is published in Nano Letters.

Chromosome analyses of prickly pear cacti reveal southern glacial refugia

Analysis of chromosome number variation among species of a North American group of prickly pear cacti (nopales) showed that the most widespread species encountered are of hybrid origin. Those widespread species likely originated from hybridization among closely related parental species from western and southeastern North America. This study was published in the open access journal Comparative Cytogenetics.

Diabetes risk factors in young Sri Lankans much higher than previously thought

Scientists at King's College London and the National Diabetes Centre (Sri Lanka) have found evidence of a high number of risk factors for type 2 diabetes among the young urban population in Sri Lanka. The study is the first large-scale investigation into diabetes risk among children and young people in South Asia, and provides further evidence that the region is rapidly becoming a hotspot in the growing international diabetes epidemic.

Critical element that improves vascular function in postmenopausal women found

AURORA, Colo. – Researchers studying why arteries stiffen in postmenopausal women have found a specific chemical cofactor that dramatically improves vascular function.

Kerrie Moreau, Ph.D., Associate Professor of Medicine at the University of Colorado School of Medicine, discovered that BH4 or tetrahydrobiopterin plays a key role in arterial health of women. BH4 is a critical cofactor of the enzyme endothelial nitric oxide synthase or eNOS. The two combine to create nitric oxide which is highly beneficial to arterial health.

Study finds injectable treatment for blood clots in advanced cancer patients increases

DENVER – The use of an injectable, clot-preventing drug known as Low Molecular Weight Heparin to treat patients with advanced cancer complicated by blood clots increased steadily between 2000 and 2007, according to a new study published in The Oncologist, funded by the National Cancer Institute and led by Kaiser Permanente Colorado. However, despite previous research indicating LMWH is the preferred first-line treatment for cancer patients experiencing blood clots, use of LMWH is low compared to another commonly used anticoagulant, warfarin.

New analysis provides clearer picture of cancer risks associated with Lynch syndrome

People with Lynch syndrome have a genetic mutation that gives them a high risk of several types of cancer including bowel cancer. The genes that are damaged can't repair any errors that occur in our DNA.

The study, which has been published in the Journal of Clinical Oncology, confirmed the increased risk of cancers already known to be associated with Lynch syndrome, including colon, uterus, ovary, kidney, stomach, and bladder cancers. They also found those with Lynch syndrome faced a moderately increased risk of developing breast and pancreatic cancer.

Malaria parasite goes bananas before sex: New study

New research from the University of Melbourne shows how the malaria parasite (Plasmodium falciparum) changes into a banana shape before sexual reproduction, a finding that could provide targets for vaccine or drug development and may explain how the parasite evades the human immune system.

The work was conducted by an Australian research team led by Dr Matthew Dixon and PhD student Megan Dearnley from the Department of Biochemistry and Molecular Biology, Bio21 Institute at the University of Melbourne, and is published in the Journal of Cell Science today.

Online role-playing games hurt marital satisfaction, says BYU study

Online role playing games negatively affect real-life marital satisfaction, according to a new Brigham Young University study to be published February 15th in the Journal of Leisure Research.

UK cases of progressive sight loss condition set to rise a third by 2020

New cases of the progressive sight loss condition, known as age-related macular degeneration, or AMD for short, are set to rise by a third in the UK over the next decade, reveals research published online in the British Journal of Ophthalmology.

AMD, which comprises "dry" (geographical atrophy) and "wet" (neovascular AMD) forms, accounts for over half of the total number of those registered blind and partially sighted in the UK.