Body

A University of Colorado Cancer Center study recently published in the journal Cell Reports and presented today at the American Association for Cancer Research (AACR) Annual Conference 2014 shows that the cellular process of autophagy in which cells "eat" parts of themselves in times of stress may allow cancer cells to recover and divide rather than die when faced with chemotherapies.

San Diego, CA – April 5, 2014 – Helping doctors monitor their melanoma patients' progress in response to treatment is just one of the many exciting applications of Bio-Rad's Droplet Digital PCR (ddPCR™) technology being showcased at the 2014 American Association for Cancer Research (AACR) Annual Meeting taking place in San Diego, CA from April 5-9.

A study by researchers at the University of Geneva concludes that prevalent ankle fractures should be considered as osteoporotic fractures and taken into account in fracture-risk assessment.

The research was presented at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases in Seville, Spain.

After vertebral fractures, ankle fractures are among the most common fractures in adults. The objective of this study was to investigate the association between bone microstructure in women at the age of 65 and prevalent ankle fracture.

The results of a study presented today at the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases do not support the hypothesis that calcium supplementation, with or without vitamin D, increases coronary heart disease or all-cause mortality risk in elderly women.

Vienna, Austria: A new genetic "signature" to identify prostate cancer patients who are at high risk of their cancer recurring after surgery or radiotherapy has been developed by researchers in Canada, the 33rd conference of the European Society for Radiotherapy and Oncology (ESTRO33) in Vienna will hear today (Saturday).

Undocked working dogs in Scotland are at greatest risk of tail injuries, indicates a survey of their owners, published in this week's Veterinary Record.

In captivity, grey parrots are often kept in social isolation, which can have detrimental effects on their health and wellbeing. So far there have not been any studies on the effects of long term social isolation from conspecifics on cellular aging. Telomeres shorten with each cell division, and once a critical length is reached, cells are unable to divide further (a stage known as 'replicative senescence'). Although cellular senescence is a useful mechanism to eliminate worn-out cells, it appears to contribute to aging and mortality.

RIVERSIDE, Calif. — A research team led by a cell biologist at the University of California, Riverside has generated a 3D model of the human malaria parasite genome at three different stages in the parasite's life cycle — the first time such 3D architecture has been generated during the progression of the life cycle of a parasite.

Death is not distributed equally around the world. In high-income countries, people typically die in old age of chronic diseases such as cancer or cardiovascular problems. In low-income countries, death comes primarily from infectious and perinatal diseases, and strikes at a young age.

A University of Colorado Cancer Center study published today in Journal of the National Cancer Institute (with related research being presented this weekend at the American Association for Cancer Research Annual Conference 2014) details the discovery of a new genetic driver of bladder cancer: silencing of the gene AGL.

BUFFALO, N.Y. – The Effects of Aspirin in Gestation and Reproduction (EAGeR) medical trial has found that, in general, low-dose aspirin is not beneficial for future pregnancy outcomes in women with prior pregnancy loss.

However, in women with one pregnancy loss within the previous 12 months, there did appear to be a benefit.

(Lebanon, NH, 04/04/14) — More than 15 years ago, many states and tobacco manufacturers established restrictions to prevent youth exposure to the marketing of nicotine products. This follows regulations imposed 50 years ago that banned cigarette ads from TV. Despite these continued efforts, a new study by Dartmouth researchers reveals that not only are young people exposed to tobacco marketing, they are influenced by it. According to a study published in the Journal of Adolescent Health, exposure to "direct marketing" is associated with increased use of tobacco.

If you are a middle-aged African-American or Asian woman, your social class may play a significant role in how likely you are to suffer bone fractures, a UCLA-led study suggests.

The study, published in the current issue of Osteoporosis International, is unique in that it followed Asian, African-American and white women for a period of nine years during mid-life; most previous studies on socioeconomic status and osteoporosis risk had focused solely on older white women and often had not collected information on fractures over time.

SAN DIEGO — Obese male mice and normal weight female mice produce female pups that are overweight at birth and in childhood, and have increased number of "terminal end buds" in their breast tissue — the site where cancer often develops in rodents.

The findings, presented by a Georgetown Lombardi Comprehensive Cancer Center researcher at the AACR Annual Meeting 2014, come from one of the first animal studies to examine the impact of paternal obesity on future generations' cancer risk.

PHILADELPHIA—(April 4, 2014)— Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 American Association for Cancer Research Annual Meeting in San Diego, researchers from The Wistar Institute will present findings that suggest the colon "microbiome" of gut bacteria can change the tumor microenvironment in a way that promotes the growth and spread of tumors.