Body

MSU physicists push new Parkinson's treatment toward clinical trials

EAST LANSING, Mich. --- The most effective way to tackle debilitating diseases is to punch them at the start and keep them from growing.

Research at Michigan State University, published in the Journal of Biological Chemistry, shows that a small "molecular tweezer" keeps proteins from clumping, or aggregating, the first step of neurological disorders such as Parkinson's disease, Alzheimer's disease and Huntington's disease.

The anti-inflammatory factory

Russian scientists, in collaboration with their colleagues from Pittsburgh University, find how lipid mediators are produced. The relevant paper was publish in Nature Chemistry. Lipid mediators are molecules playing an important role in inflammation process. A study devoted to some of them has earned a Nobel prize in 1982.

IU study: Death of public figures provides important opportunities for health education

BLOOMINGTON, Ind. -- An Indiana University study of reactions to the 2011 death of Apple co-founder Steve Jobs suggests health communicators have a critical window of opportunity after a public figure dies to disseminate information about disease prevention and detection.

The study, involving a survey of 1,400 adult men and women, found that immediately after Jobs' death, more than a third of survey participants sought information about how he died or about cancer in general, and 7 percent sought information about pancreatic cancer, the disease that took Jobs' life.

Edible flowers may inhibit chronic diseases

A new study in the Journal of Food Science, published by the Institute of Food Technologists (IFT), found that common edible flowers in China are rich in phenolics and have excellent antioxidant capacity. Edible flowers, which have been used in the culinary arts in China for centuries, are receiving renewed interest. Flowers can be used as an essential ingredient in a recipe, provide seasoning to a dish, or simply be used as a garnish.

Regulating legal marijuana could be guided by lessons from alcohol and tobacco, study says

As U.S. policymakers consider ways to ease prohibitions on marijuana, the public health approaches used to regulate alcohol and tobacco over the past century may provide valuable lessons, according to new RAND Corporation research.

Recent ballot initiatives that legalized marijuana in Colorado and Washington for recreational uses are unprecedented. The move raises important questions about how to best allow the production, sales and the use of marijuana while also working to reduce any related social ills.

Ginseng can treat and prevent influenza and RSV, researcher finds

ATLANTA--Ginseng can help treat and prevent influenza and respiratory syncytial virus (RSV), a respiratory virus that infects the lungs and breathing passages, according to research findings by a scientist in Georgia State University's new Institute for Biomedical Sciences.

In a recent issue of Nutrients and an upcoming publication of the International Journal of Molecular Medicine, Sang-Moo Kang reports the beneficial effects of ginseng, a well-known herbal medicine, on human health.

More questions than answers as mystery of domestication deepens

We all think we have a rough idea of what happened 12,000 years ago when people at several different spots around the globe brought plants under cultivation and domesticated animals for transport, food or fiber. But how much do we really know?

Why alcoholism saps muscle strength

(PHILADELPHIA) -- Muscle weakness is a common symptom of both long-time alcoholics and patients with mitochondrial disease. Now researchers have found a common link: mitochondria that are unable to self-repair. The results will be published online April 21 in The Journal of Cell Biology. The link to self-repair provides researchers both a new way to diagnose mitochondrial disease, and a new drug target.

Birthplace of the domesticated chili pepper identified in Mexico

Central-east Mexico gave birth to the domesticated chili pepper — now the world's most widely grown spice crop — reports an international team of researchers, led by a plant scientist at the University of California, Davis.

A protein required for integrity of induced pluripotent stem cells

Cell reprogramming converts specialised cells such as nerve cells or skin cells towards an embryonic stem cell state. This reversal in the evolutionary development of cells also requires a reversal in the biology of telomeres, the structures that protect the ends of chromosomes; whilst under normal conditions telomeres shorten over time, during cell reprogramming they follow the opposite strategy and increase in length.

UCSF study finds codeine often prescribed to children, despite available alternatives

Despite its potentially harmful effects in children, codeine continues to be prescribed in U.S. emergency rooms, according to new research from UCSF Benioff Children's Hospital San Francisco.

As reported in the May issue of Pediatrics, solutions include changing provider prescription behaviors to promote the use of better alternatives to codeine, such as ibuprofen or hydrocodone.

Computational method dramatically speeds up estimates of gene expression

PITTSBURGH—With gene expression analysis growing in importance for both basic researchers and medical practitioners, researchers at Carnegie Mellon University and the University of Maryland have developed a new computational method that dramatically speeds up estimates of gene activity from RNA sequencing (RNA-seq) data.

Cancer stem cells linked to drug resistance

Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells.

Study of gut microbes, antibiotics: Clues to improving immunity in premature infants

Mothers give a newborn baby a gift of germs—germs that help to kick-start the infant's immune system. But antibiotics, used to fend off infection, may paradoxically interrupt a newborn's own immune responses, leaving already-vulnerable premature babies more susceptible to dangerous pathogens.

A new animal study by neonatology researchers at The Children's Hospital of Philadelphia (CHOP) sheds light on immunology in newborns by revealing how gut microbes play a crucial role in fostering the rapid production of infection-fighting white blood cells, called granulocytes.

Dana-Farber researchers uncover link between Down syndrome and leukemia

BOSTON –Although doctors have long known that people with Down syndrome have a heightened risk of developing acute lymphoblastic leukemia (ALL) during childhood, they haven't been able to explain why. Now, a team of Dana-Farber Cancer Institute investigators has uncovered a connection between the two conditions.