Body

NIH study links high cholesterol levels to lower fertility

High cholesterol levels may impair fertility in couples trying to achieve a pregnancy, according to a study by researchers at the National Institutes of Health, the University at Buffalo (New York), and Emory University in Atlanta.

Couples in which each partner had a high cholesterol level took the longest time to reach pregnancy. Moreover, couples in which the woman had a high cholesterol level and the man did not also took longer to achieve pregnancy when compared to couples in which both partners had cholesterol levels in the acceptable range.

Key genetic link between chronic pain conditions like IBS discovered

Researchers at King's College London have discovered a link between four common chronic pain syndromes (CPS), suggesting that some people may be genetically predisposed to suffer from conditions of this type. The study, published in the journal Pain, examined identical and non-identical twins and established that IBS, musculoskeletal pain, pelvic pain and dry eye disease may have hereditary links. Migraine was shown, as previously, to have a degree of genetic susceptibility but was not genetically linked to the other conditions.

Groundbreaking vaccine research unveiled at AAPS National Biotechnology Conference

SAN DIEGO (May 20, 2014) - Innovative vaccine research will be unveiled at the American Association of Pharmaceutical Scientists' (AAPS) National Biotechnology Conference (NBC). The meeting takes place Monday, May 19- Wednesday, May 21 at the Sheraton San Diego Hotel and Marina.

Designing a Novel Freeze-Stable Tetanus Vaccine

According to the World Health Organization, over half of all vaccines worldwide are destroyed due to freeze-damage. A lot of research is currently being conducted about issues associated with the cold-chain and freeze-damage of vaccines.

A full serving of protein at each meal needed for maximum muscle health

Most Americans eat a diet that consists of little to no protein for breakfast, a bit of protein at lunch and an overabundance of protein at dinner. As long as they get their recommended dietary allowance of about 60 grams, it's all good, right?

Boosting Immune process with IFN-γ helps clear lethal bacteria in cystic fibrosis

Boosting a key immune process called autophagy with interferon gamma (IFN-γ) could help clear a lethal bacterial infection in cystic fibrosis, a new study suggests. The work, led by a team in The Research Institute at Nationwide Children's Hospital and published in PLoS One in May, offers new information about immune function in patients with the disease.

Scientists study biomechanics behind amazing ant strength

A recent study into the biomechanics of the necks of ants – a common insect that can amazingly lift objects many times heavier than its own body – might unlock one of nature's little mysteries and, quite possibly, open the door to advancements in robotic engineering.

Screen of existing drugs finds compounds active against MERS coronavirus

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Detroit Lions help rebuild city with innovative gridiron giving, U-M researchers say

ANN ARBOR—The Detroit Lions' new model of philanthropy and community engagement may prove to be a touchdown for the city of Detroit.

A new case study of corporate social responsibility in sport by University of Michigan researchers uses the Lions as an exemplar of a professional sports team reinventing its charitable giving and community relations approach in hopes of making a bigger impact on the community.

Stem cells as a future source for eco-friendly meat

The scientific progress that has made it possible to dream of a future in which faulty organs could be regrown from stem cells also holds potential as an ethical and greener source for meat. So say scientists who suggest in the Cell Press journal Trends in Biotechnology that every town or village could one day have its very own small-scale, cultured meat factory.

First Nations people less likely to receive coronary angiography after heart attack

First Nations people are less likely to receive guideline-recommended angiography after a heart attack compared with non–First Nations people and have poorer long-term survival rates, according to new research published in CMAJ (Canadian Medical Association Journal).

First Nations people in Canada have a 2.5-fold higher prevalence of heart disease compared with non–First Nations people and increasing rates of hospitalization for cardiovascular health issues.

Unlocking the potential of bacterial gene clusters to discover new antibiotics

Resistance to antibiotics has been steadily rising, posing a threat to public health. Now, a method from Mohammad Seyedsayamdost, an assistant professor of chemistry at Princeton University, may open the door to the discovery of a host of potential drug candidates.

The vast majority of anti-infectives on the market today are bacterial natural products, made by biosynthetic gene clusters. Genome sequencing of bacteria has revealed that these active gene clusters are outnumbered approximately ten times by so-called silent gene clusters.

NIH researchers discover key factor in early auditory system development

Researchers at the National Institutes of Health have uncovered a molecule in an animal model that acts as a key player in establishing the organization of the auditory system. The molecule, a protein known as Bmp7, is produced during embryonic development and acts to help sensory cells find their ultimate position on the tonotopic map, which is the fundamental principle of organization in the auditory system. The tonotopic map groups sensory cells by the sound frequencies that stimulate them. The study is the first to identify one of the molecular mechanisms that determines position.

Engineers build world's smallest, fastest nanomotor

Researchers at the Cockrell School of Engineering at The University of Texas at Austin have built the smallest, fastest and longest-running tiny synthetic motor to date. The team's nanomotor is an important step toward developing miniature machines that could one day move through the body to administer insulin for diabetics when needed, or target and treat cancer cells without harming good cells.

Termite genome lays roadmap for 'greener' control measures

WEST LAFAYETTE, Ind. - A team of international researchers has sequenced the genome of the Nevada dampwood termite, providing an inside look into the biology of the social insect and uncovering new genetic targets for pest control.

Michael Scharf, a Purdue University professor of entomology who participated in the collaborative study, said the genome could help researchers develop control strategies that are more specific than the broad-spectrum chemicals conventionally used to treat termite infestations.

Microbes from 1,500-year-old feces support archeological theories

By evaluating the bacteria and fungi found in fossilized feces, microbiologists are providing evidence to help support archeologists' hypotheses regarding cultures living in the Caribbean over 1,500 years ago. They report their findings today at the annual meeting of the American Society for Microbiology.