Body

Virus rounds up enzymes, disarms plant

University of Tokyo researchers have described how a plant-virus protein suppresses an important plant defense mechanism that remembers viral genetic information, providing a new target for developing the first-ever chemical against plant viruses that globally cause more than $60 billion of crop losses each year.

New Population Council research presented at 13th ESC Annual Congress

LISBON, PORTUGAL (31 May 2014) – This week, the Population Council presented new research at the 13th Congress of the European Society of Contraception and Reproductive Health. Presentations included a pharmacokinetic analysis of the Council's investigational one-year contraceptive vaginal ring containing Nestorone® and ethinyl estradiol, and its investigational male contraceptive implant MENT®, as well as new approaches to "green contraception," including strategies to ensure that future contraceptive technologies are both effective and protect the environment.

Clinical trial shows drug combination may be effective in recurrent ovarian cancer

Patients, whose median age was 58, were enrolled from October 2011 to June 2013. As of March 2014, median progression-free survival was 9.2 months for olaparib and 16.7 months for the combination therapy, which is a significant advantage. The overall rate of toxicity was higher for patients on the combination therapy. Fatigue, diarrhea, and hypertension were the most common toxic effects, all of which were manageable.

New data shows ProMark accurately predicts aggressive prostate cancer, pathology outcomes

CAMBRIDGE, Massachusetts, June 2, 2014 – Today, for the first time, Metamark presents results from the clinical validation study that showed ProMark™, the first and only proteomic-based imaging biopsy test, achieved its primary endpoint by accurately differentiating between aggressive and non-aggressive forms of prostate cancer at early stages of disease. ProMark™ was shown to predict which patients have low-risk disease with a sensitivity of 90 percent or better, confidently identifying patients who are appropriate for active surveillance or need aggressive therapy.

A master of disguise: A new stick insect species from China

Many representatives of the fauna possess unique masking abilities but stick insects are among the masters of disguise within the animal world. During a field trip in Guangxi, China Mr. Ho Wai-chun George from the Hong Kong Entomological Society discovers a new species from this enigmatic insect group, which he describes in a recent research paper published in the open access journal Deutsche Entomologische Zeitschrift.

New species from the past

A piece of Eocene Baltic Amber of about 45 million years age contains a well preserved extinct flat bug, which turned out to be a new species to science. This exciting discovery is one of the many secrets that deposits of Baltic amber have revealed in the last years and are yet to come in the future. The study describing the new species was published in the open access journal Deutsche Entomologische Zeitschrift.

What finding out a child's sex before birth says about a mother

COLUMBUS, Ohio – An expectant mother who chooses to find out her child's sex before birth may be giving subtle clues about her views on proper gender roles, new research suggests.

The study found that women who choose not to learn their child's sex may be more open to new experiences, and combine egalitarian views about the roles of men and women in society with conscientiousness.

On the other hand, expectant mothers who scored high on a test of parenting perfectionism were more likely than others to learn their baby's sex.

DREAM project crowdsources answer to cancer cell drug sensitivities

A study published June 1 in the journal Nature Biotechnology describes the results of an open challenge to predict which breast cancer cell lines will respond to which drugs, based only on the sum of cells' genomic data. The winning entry, from the Helsinki Institute for Information Technology, was 78 percent accurate in identifying sensitive versus resistant cell lines, and was one of 44 algorithms submitted by groups from around the world.

Stronger than steel

A Swedish-German research team has successfully tested a new method for the production of ultra-strong cellulose fibres at DESY's research light source PETRA III. The novel procedure spins extremely tough filaments from tiny cellulose fibrils by aligning them all in parallel during the production process. The new method is reported in the scientific journal Nature Communications.

Myriad myPath melanoma test improves the reliability of melanoma diagnosis

SALT LAKE CITY, Utah, June 2, 2014 – Myriad Genetics, Inc. (Nasdaq: MYGN) today presented results from a pivotal clinical validation study of the Myriad myPath™ Melanoma test at the 2014 American Society of Clinical Oncology (ASCO) annual meeting in Chicago, Ill. The Myriad myPath Melanoma test is a novel molecular test that accurately differentiates malignant melanoma from benign skin lesions with a high level of accuracy and helps physicians deliver a more objective and confident diagnosis for patients.

Myriad presents clinical data on Myriad myRisk Hereditary Cancer Test at ASCO

SALT LAKE CITY, Utah, June 2, 2014 – Myriad Genetics, Inc. (Nasdaq: MYGN) today presented several clinical studies on the Myriad myRisk™ Hereditary Cancer test at the 2014 American Society of Clinical Oncology (ASCO) annual meeting in Chicago, Illinois. Among the important new findings is that the myRisk test detects significantly more deleterious mutations than single cancer tests and helps solve the overlap dilemma that exists among hereditary cancer syndromes.

New research shows parental presence improves the quality of child anesthesia

New research presented at this year's Euroanaesthesia meeting in Stockholm shows that having parents present during the induction of their child's anaesthesia improves the quality of that anaesthesia. The study is by Dr Alicia Sánchez, Department of Anaesthesiology, Hospital de Sagunto, Spain, and colleagues.

Children exposed to secondhand tobacco or cooking smoke have very high rates of pain and complications after tonsillectomy

New research presented at this year's Euroanaesthesia meeting in Stockholm shows that children exposed to indoor coal-burning stoves and/or second-hand tobacco smoke are much more likely to suffer postoperative complications and excessive pain after tonsillectomies. The research is by Professor Daniel Sessler, Cleveland Clinic, Cleveland, Ohio, USA and Dr Onur Koyuncu, Mustafa Kemal University, Hatay, Turkey, and colleagues.

Deletions and duplications in the exome can help pinpoint cause of unexplained genetic diseases

Analysis of genetic variation in the exome, the DNA sequence of genes that are translated into protein, can aid in uncovering the cause of conditions for which no genetic cause could previously be found, and this can directly impact clinical management, the annual conference of the European Society of Human Genetics will hear today.

New genes involved in food preferences will revolutionize diets and improve health

New understanding of the genes involved in taste perception and food preferences could lead to personalised nutrition plans effective not just in weight loss but in avoiding diseases such as cancer, depression, and hypertension, Italian researchers will tell the annual conference of the European Society of Human Genetics (ESHG) today (Monday).