Bottom Line: Very-low-birth-weight (VLBW) babies who undergo major surgery appear to have an increased risk of death or subsequent neurodevelopmental impairment (NDI).
Author: Frank H. Morriss, Jr., M.D., M.P.H., of the University of Iowa, Iowa City, and colleagues.
Background: Some animal studies suggest general anesthesia for surgery can increase the risk for neurocognitive or behavioral deficits. This has raised some concerns about exposing infants to general anesthesia for surgery.