Body

A simple point-of-care testing device for anemia could provide more rapid diagnosis of the common blood disorder and allow inexpensive at-home self-monitoring of persons with chronic forms of the disease.

The disposable self-testing device analyzes a single droplet of blood using a chemical reagent that produces visible color changes corresponding to different levels of anemia. The basic test produces results in about 60 seconds and requires no electrical power. A companion smartphone application can automatically correlate the visual results to specific blood hemoglobin levels.

WINSTON-SALEM, N.C. – Sept. 11, 2014 – Meditation might be a path to migraine relief, according to a new study by researchers at Wake Forest Baptist Medical Center.

"Stress is a well-known trigger for headaches and research supports the general benefits of mind/body interventions for migraines, but there hasn't been much research to evaluate specific standardized meditation interventions," said Rebecca Erwin Wells, M.D., assistant professor of neurology at Wake Forest Baptist and lead author of the study published in the online edition of the journal Headache.

In recovery from the deadly legacy of DDT, American peregrine falcons (Falco peregrines anatum) faced new uncertainty in 1992, when biologists proposed to stop rearing young birds in captivity and placing them in wild nests. Tim Wootton and Doug Bell published models that year in ESA's journal Ecological Applications, projecting population trends for the falcon in California, with and without direct human intervention in the falcons' reproductive lives.

Two Northeastern University researchers and their international colleagues have created an advanced model aimed at exploring the role of neutral evolution in the biogeographic distribution of ocean microbes.

Inflammation may be the reason high blood sugar levels damage blood vessels, raising the possibility that anti-inflammatory medications might someday be used to lower the risk of blood vessel disease in people with diabetes, according to a study presented at the American Heart Association's High Blood Pressure Research Scientific Sessions 2014.

One in six cancer patients enroll in hospice only during their last three days of life, according to a new study from a team from the Perelman School of Medicine at the University of Pennsylvania. Their findings, published online last month in the Journal of Clinical Oncology (JCO) also reveal a profile of patients who may be most at risk of these late admissions.

Dartmouth researchers have found that the genetic mutation BRAFV600E, frequently found in metastatic melanoma, not only secretes a protein that promotes the growth of melanoma tumor cells, but can also modify the network of normal cells around the tumor to support the disease's progression. Targeting this mutation with Vemurafenib reduces this interaction, and suggests possible new treatment options for melanoma therapy.

Dartmouth researchers have found that African American women are 55 percent less likely to receive breast reconstruction after mastectomy regardless of where they received their care. They report on their findings in "The influence of race/ethnicity and place of service on breast reconstruction for Medicare beneficiaries with mastectomy," recently published in SpringerPlus.

Studies in mice demonstrate that signals from the bacteria that harmlessly—and often beneficially—inhabit the human gastrointestinal tract boost the immune system's ability to kill a major respiratory pathogen, Klebsiella pneumoniae, according to a paper published online ahead of print in the journal Infection and Immunity.

The research is yet another example of how important these "commensal" bacteria are to human health and physiology, says Thomas B. Clarke, of Imperial College London, UK, the lone author of this paper.

Researchers led by Dr. Helen McNeill at the Lunenfeld-Tanenbaum Research Institute have revealed an exciting and unusual biochemical connection. Their discovery has implications for diseases linked to mitochondria, which are the primary sources of energy production within our cells.

Ann Arbor, Mich. — Primary care providers report many challenges to integrating genetics services into routine primary care, according to research published today in Genetics in Medicine.

Many pathogens are transmitted by insect bites. The abundance of vectors (as the transmitting insects are called) depends on seasonal and other environmental fluctuations. An article published on September 11thin PLOS Pathogens demonstrates that Plasmodium parasites react to mosquitoes biting their hosts, and that the parasite responses increase transmission to the mosquito vector.

Solving societal challenges in food security, emerging diseases and biodiversity loss will require evolutionary thinking in order to be effective in the long run. Inattention to this will only lead to greater challenges such as short-lived medicines and agricultural treatments, problems that may ultimately hinder sustainable development, argues a new study published online today in Science Express, led by University of California, Davis and the Center for Macroecology, Evolution and Climate at the University of Copenhagen.

Dartmouth researchers studying cell division in fruit flies have discovered a pathway that may improve understanding of molecular mistakes that cause older women to have babies with Down syndrome.

The study shows for the first time that new protein linkages occur in immature egg cells after DNA replication and that these replacement linkages are essential for these cells to maintain meiotic cohesion for long periods.

As humans transform the planet to meet our needs, all sorts of wildlife continue to be pushed aside, including many species that play key roles in Earth's life-support systems. In particular, the transformation of forests into agricultural lands has dramatically reduced biodiversity around the world.