ANN ARBOR, Mich.---A glitch in the ability to move iron around in cells may underlie a disease known as Type IV mucolipidosis (ML4) and the suite of symptoms---mental retardation, poor vision and diminished motor abilities---that accompany it, new research at the University of Michigan shows.
The same deficit also may be involved in aging and neurodegenerative diseases such as Alzheimer's and Parkinson's, says lead author Haoxing Xu, an assistant professor of molecular, cellular and developmental biology.