Body

Changes in scores of genes contribute to autism risk

Small differences in as many as a thousand genes contribute to risk for autism, according to a study led by Mount Sinai researchers and the Autism Sequencing Consortium (ASC), and published today in the journal Nature.

The new study examined data on several types of rare, genetic differences in more than 14,000 DNA samples from parents, affected children, and unrelated individuals – by far the largest number to date – to dramatically expand the list of genes identified with autism spectrum disorder (ASD).

Teeth, sex and testosterone reveal secrets of aging in wild mouse lemurs

Mouse lemurs can live at least eight years in the wild – twice as long as some previous estimates, a long-term longitudinal study finds.

PLOS ONE published the research on brown mouse lemurs (Microcebus rufus) led in Madagascar by biologist Sarah Zohdy, a post-doctoral fellow in Emory University's Department of Environmental Sciences and the Rollins School of Public Health. Zohdy conducted the research while she was a doctoral student at the University of Helsinki.

Tiny carbon nanotube pores make big impact

A team led by the Lawrence Livermore scientists has created a new kind of ion channel based on short carbon nanotubes, which can be inserted into synthetic bilayers and live cell membranes to form tiny pores that transport water, protons, small ions and DNA.

These carbon nanotube "porins" have significant implications for future health care and bioengineering applications. Nanotube porins eventually could be used to deliver drugs to the body, serve as a foundation of novel biosensors and DNA sequencing applications, and be used as components of synthetic cells.

HPV infections in women eradicated by AHCC, Japanese mushroom extract

"With this study, for the first time, we've shown it's possible to eradicate HPV in women using AHCC for only 3 months or up to 6 months," said Dr. Smith, whose research has a specific focus on the safe and effective use of nutritional and herbal supplements with pharmacologic modalities as it relates to women's health and cancer. "We've been studying the efficacy of AHCC's integration with common chemotherapy agents for over a decade, and had previously eradicated HPV infections with AHCC in three orthotopic mouse models. This study confirms the previous results," she said.

Penn vet professor investigates parasite-schizophrenia connection

Many factors, both genetic and environmental, have been blamed for increasing the risk of a diagnosis of schizophrenia. Some, such as a family history of schizophrenia, are widely accepted. Others, such as infection with Toxoplasma gondii, a parasite transmitted by soil, undercooked meat and cat feces, are still viewed with skepticism.

Clean smell doesn't always mean clean air

Some of the same chemical reactions that occur in the atmosphere as a result of smog and ozone are actually taking place in your house while you are cleaning. A researcher in Drexel's College of Engineering is taking a closer look at these reactions, which involve an organic compound -called limonene- that provides the pleasant smell of cleaning products and air fresheners. His research will help to determine what byproducts these sweet-smelling compounds are adding to the air while we are using them to remove germs and odors.

New technology on the way to aid cancer suffers who lose their hair after chemotherapy

Cancer suffers who lose their hair as a consequence of chemotherapy will benefit from a major research project that will improve the scalp cooling technology that prevents hair loss.

The research is being now underway and is being pioneered by global scalp cooling manufacturing company, Paxman Coolers, of Fenay Bridge, Huddersfield, in conjunction with the biology department of the University of Huddersfield.

The research will be led by key researcher Omar Hussain, who has a background in the pharmacology of cancer treatment, which he will use towards his PhD.

Decades of research: Effectiveness of phone counseling for cancer patients still unknown

Increasingly, cancer care respects the fact that a patient's body is only part of the system that requires treatment. Over a third of cancer patients experience psychosocial distress – the mental health consequences of their conditions. And, increasingly, care providers are exploring phone- and internet-based interventions to help cancer patients navigate mental health challenges.

Meiotic cell division 'the other way round'

Meiosis is not like another: Gabriela Cabral and Peter Schlögelhofer at the Max F. Perutz Laboratories (MFPL) of the University of Vienna and the Medical University of Vienna dived into the process of meiosis in specific plant species and revealed that these plants display an inversion of the standard meiotic phases. The researchers describe the detailed mechanisms in the scientific journal Nature Communications.

A mechanism that allows a differentiated cell to reactivate as a stem cell revealed

One kind of stem cell, those referred to as 'facultative', form part—together with other cells—of tissues and organs. There is apparently nothing that differentiates these cells from the others. However, they have a very special characteristic, namely they retain the capacity to become stem cells again. This phenomenon is something that happens in the liver, an organ that hosts cells that stimulate tissue growth, thus allowing the regeneration of the organ in the case of a transplant.

Go straight and publish: From Barcode of Life Data Systems to scholarly publishing systems

An innovative workflow reveals new research potential of the Barcode of Life Data Systems (BOLD). A recently published article in the Biodiversity Data Journal (BDJ) used specimen records downloaded from BOLD in tabular format and imported these into a human-readable text developed in manuscript within the Pensoft Writting Tool (PWT).

To reap the brain benefits of physical activity, just get moving!

This news release is available in French.

Support for fecal testing in familial colorectal cancer screening

Bethesda, MD (Oct. 29, 2014) — Fecal immunochemical tests (FIT) may be as effective as colonoscopies when it comes to detecting colorectal cancer among first-degree relatives of patients with colorectal cancer, according to a new study in Gastroenterology1, the official journal of the American Gastroenterological Association.

Microrockets fueled by water neutralize chemical and biological warfare agents

With fears growing over chemical and biological weapons falling into the wrong hands, scientists are developing microrockets to fight back against these dangerous agents, should the need arise. In the journal ACS Nano, they describe new spherical micromotors that rapidly neutralize chemical and biological agents and use water as fuel.

Why plants don't get sunburn

Plants rely on sunlight to make their food, but they also need protection from its harmful rays, just like humans do. Recently, scientists discovered a group of molecules in plants that shields them from sun damage. Now, in an article in the Journal of the American Chemical Society, one team reports on the mechanics of how these natural plant sunscreens work.