Body

Note: A graphic of the "telomerator" being inserted into a circular synthetic chromosome is available at: https://nyumc.box.com/s/zpticyfat5479vcnl9y8

NYU Langone yeast geneticists report they have developed a novel tool — dubbed "the telomerator" — that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism's genetic, chemical base-pair structure.

When fossil fuels are burned, other climate-forcing gases are produced in addition to long-lasting carbon dioxide. Diesel combustion in vehicles or coal in power plants creates soot particles, which also contribute to global warming, albeit only briefly as they disappear quickly from the atmosphere. Short-lived climate pollutants (also known as Short Lived Climate Forcers or SLCF) caused by human activities include methane and sulphur dioxide, and to a lesser extent fluorocarbons. They all have a measurable impact on the climate.

The pathogen Giardia duodenalis is present in mussels from freshwater run-off sites and from areas where California Sea Lions lounge along the coast of California, according to a team of researchers from the University of California, Davis. One of the G. duodenalis strains found is known to infect humans; the two others occur mostly in dogs and other canids. "Thus, the detection of these assemblages implies a potential public health risk if consuming fecally contaminated water or uncooked shellfish," says coauthor Woutrina Smith.

NEW ORLEANS (November 3, 2014)—The majority of malaria hospitalizations in Malaysia are now caused by a dangerous and potentially deadly monkey-borne parasite once rarely seen in humans, and deforestation is the potential culprit in a growing number of infections that could allow this virulent malaria strain to jump from macaque monkeys to human hosts, according to research presented today at the American Society of Tropical Medicine and Hygiene (ASTMH) Annual Meeting.

Researchers from the Johns Hopkins Bloomberg School of Public Health have developed a test they say will allow them to test thousands of FDA-approved drugs to see if they will work against the bacteria that causes tick-borne Lyme disease.

San Diego — A nasal vaccine in development by researchers at The University of Texas at Austin has been shown to provide long-term protection for non-human primates against the deadly Ebola virus. Results from a small pre-clinical study represent the only proof to date that a single dose of a non-injectable vaccine platform for Ebola is long-lasting, which could have significant global implications in controlling future outbreaks. This work is being presented Nov.

CORVALLIS, Ore. – A broad review of the use of medications to reduce blood pressure has confirmed that "mild" control of systolic pressure is adequate for adults age 65 or older - in the elderly, there's no clear benefit to more aggressive use of medications to achieve a lower pressure.

AUSTIN, Texas—A potentially breathable, respiratory vaccine in development has been shown to provide long-term protection for non-human primates against the deadly Ebola virus, as reported this week in the online edition of the journal Molecular Pharmaceutics.

Ever walked into a hotel room and smelled old cigarette smoke? While the last smoker may have left the room hours or even days ago, the lingering odors—resulting from noxious residue that clings to walls, carpets, furniture, or dust particles—are thanks to thirdhand smoke.

Aging is the most significant and universal risk factor for developing neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) and Alzheimer's, Parkinson's and Huntington's diseases. This risk increases disproportionately with age, but no one really knows why.

For the first time, researchers have shown that practising mindfulness meditation or being involved in a support group has a positive physical impact at the cellular level in breast cancer survivors.

A group working out of Alberta Health Services' Tom Baker Cancer Centre and the University of Calgary Department of Oncology has demonstrated that telomeres – protein complexes at the end of chromosomes – maintain their length in breast cancer survivors who practise meditation or are involved in support groups, while they shorten in a comparison group without any intervention.

BOSTON—New research reports that preoperative pain and depressive symptoms in older adults place them at greater risk of delirium following surgery. According to the findings published today in The Lancet Psychiatry journal, both pain and depression are independent and interactive risk factors for delirium, suggesting a cumulative effect.

Virginia Commonwealth University (VCU) Massey Cancer Center researchers have developed the first and only tool that can accurately measure cancer health literacy (CHL) and quickly identify patients with limited CHL. This tool has the potential to improve communication and understanding between physicians and patients, which, in turn, could lead to better clinical outcomes.

San Diego — A nasal vaccine in development by researchers at The University of Texas at Austin has been shown to provide long-term protection for non-human primates against the deadly Ebola virus. Results from a small pre-clinical study represent the only proof to date that a single dose of a non-injectable vaccine platform for Ebola is long-lasting, which could have significant global implications in controlling future outbreaks. This work is being presented Nov.

TORONTO, ON, Nov. 3, 2014 — Women who have been previously hospitalized for bipolar disorder are nearly twice as likely to have premature babies compared to women without a history of mental illness, according to a new study by researchers at Women's College Hospital and the Institute for Clinical Evaluative Sciences (ICES).