Body

New prognostic tool accurately predicts mortality risk in pediatric septic shock

CINCINNATI - Researchers have developed a tool that allows caregivers to quickly and accurately predict the risk of death in children with septic shock – a systemic infection that damages vital organs and one of the leading causes of death among hospitalized children.

Reporting their results Jan. 29 in PLOS ONE (published by the Public Library of Science), researchers say the study validates a tool that would let doctors decide much faster which severely sick children need to receive aggressive life-saving therapy.

Slow reaction time linked with early death

Having a slow reaction time in midlife increases risk of having died 15 years later, according to new research published in the journal PLOS ONE.

Connectedness, human use of buildings shape indoor bacterial communities

The location, connectedness, and human use patterns in a building may influence the types of bacteria they house, according to a study published in PLOS ONE on January 29, 2014 by Steven Kembel from the University of Québec in Montréal, Canada and colleagues.

Oregon researchers show how building design impacts indoor bacteria

EUGENE, Ore. -- The Lillis Business Complex set the bar for sustainable buildings 10 years ago when it opened at the University of Oregon. Now microbes drawn from the dust in 155 of its rooms have provided clues that could inspire future architectural designers to encourage a healthy indoor environment.

Researchers discover treatment for rare blood cancer

University of British Columbia researchers have discovered a potential new treatment for a rare blood cancer that may also point the way to treating other more common diseases.

Paroxysmal nocturnal hemoglobinemia (PNH) is a rare form of cancer characterized by episodic rupture of red blood cells and the danger of blood clots forming in the vascular system. The condition results in red blood cells becoming vulnerable to attacks by the body's own complement immune system and can lead to complications such as anemia, kidney disease and fatal thromboses.

Scientists shine spotlight on Herdwicks' origins

A new study highlights surprising differences between Herdwick sheep and their closest neighbouring UK upland breeds.

The research, led by The Sheep Trust, a national charity based at the University of York, is the first of its kind to compare the genetics of three commercially farmed breeds all concentrated in the same geographical region of the UK.Scientists worked with hill farmers to explore the genetic structures of Herdwicks, Rough Fells and Dalesbred, breeds locally adapted to the harsh conditions of mountains and moorlands.

Improved ultrasound imaging provides alternate way to visualize tumors

CHAPEL HILL, NC – While ultrasound provides a less expensive and radiation-free alternative to detecting and monitoring cancer compared to technologies such as X-rays, CT scans, and MRIs, ultrasound has seen limited use in cancer treatment due to clarity and resolution issues. But researchers at the UNC School of Medicine have overcome this limitation by combining ultrasound with a contrast agent composed of tiny bubbles that pair with an antibody that many cancer cells produce at higher levels than do normal cells.

Dinosaur fossils from China help Penn researchers describe new 'Titan'

A team led by University of Pennsylvania paleontologists has characterized a new dinosaur based on fossil remains found in northwestern China. The species, a plant-eating sauropod named Yongjinglong datangi, roamed during the Early Cretaceous period, more than 100 million years ago. This sauropod belonged to a group known as Titanosauria, members of which were among the largest living creatures to ever walk the earth.

Less than half of children treated for anxiety achieve long-term relief

Fewer than one in two children and young adults treated for anxiety achieve long-term relief from symptoms, according to the findings of a study by investigators from the Johns Hopkins Children's Center and five other institutions.

Findings point to potential treatment for virus causing childhood illnesses

WEST LAFAYETTE, Ind. - Researchers have discovered a potential treatment for a viral infection that causes potentially fatal brain swelling and paralysis in children. The findings also point to possible treatments for related viruses including those that cause "common cold" symptoms.

Two stressed people equals less stress

Does giving a speech in public stress you out? Or writing a big presentation for your boss? What about skydiving?

One way to cope, according to a new study from Sarah Townsend, assistant professor of management and organization at the USC Marshall School of Business, is to share your feelings with someone who is having a similar emotional reaction to the same scenario.

Extended outcomes from APBI show tumor control, breast cosmesis and minimal late toxicity

Fairfax, Va., January 29, 2014— Long-term (five-year) outcomes of breast cancer patients receiving adjuvant accelerated partial breast irradiation (APBI) after breast-conserving surgery show excellent tumor control and breast cosmesis (cosmetic outcomes) with minimal late toxicity, according to a study published in the February 1, 2014 print edition of the International Journal of Radiation Oncology • Biology • Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO).

EBRT reduces risk of subsequent mastectomy in patients with invasive breast cancer

Fairfax, Va., January 29, 2014— Standard external beam radiation therapy (EBRT) provided a higher breast preservation rate than brachytherapy in women age 66 and older with invasive breast cancer, according to a study published in the February 1, 2014 print edition of the International Journal of Radiation Oncology • Biology • Physics (Red Journal), the official scientific journal of the American Society for Radiation Oncology (ASTRO).

Screening for transformed human mesenchymal stromal cells with tumorigenic potential

Researchers at Erasmus University Medical Center Rotterdam, The Netherlands, led by Dr. Qiuwei Pan and Dr. Luc van der Laan, have discovered that spontaneous tumorigenic transformation of human mesenchymal stem/stromal cells (MSCs) can occur during cell culture expansion, although the frequency is relatively low and often only observed after extensive passage in culture. This report appears in the January 2014 issue of Experimental Biology and Medicine.

Study uncovers molecular keys to invasive bladder cancer

HOUSTON – The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.