Body

Delivering a 1-2 punch: New drug combination shows promise in treating breast cancer

The uncontrolled growth of cancer cells arises from their ability to hijack the cell's normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for the cancer cell to survive. The answer, say Case Western Reserve researchers, is to anticipate and block that back-up track by prescribing two drugs from the start.

Study: Prompt isolation of symptomatic patients is key to eliminating Ebola

1. Study: Prompt isolation of symptomatic patients is key to eliminating Ebola

Study may explain why targeted drug doesn't benefit patients with early-stage lung cancer

COLUMBUS, Ohio – The drug erlotinib is highly effective in treating advanced-stage lung cancer patients whose tumors have a particular gene change, but when the same drug is used for patients with early-stage tumors with the same gene change, they actually fare worse than if they took nothing. A study by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and at Cincinnati Children's Hospital might show why.

Delivering a one-two punch: New drug combination shows promise in treating breast cancer

The uncontrolled growth of cancer cells arises from their ability to hijack the cell's normal growth program and checkpoints. Usually after therapy, a second cancer-signaling pathway will open after the primary one shuts down — creating an ingenious escape route for the cancer cell to survive. The answer, say Case Western Reserve researchers, is to anticipate and block that back-up track by prescribing two drugs from the start.

UH research focuses on suicide resilience and vulnerability

Religious beliefs and practices may reduce thoughts of suicide among African-American adults in stressful life events induced by racial discrimination, according to a new research study conducted at the University of Houston (UH).

Synapses always on the starting blocks

This news release is available in German.

Prostate cancer, kidney disease detected in urine samples on the spot

When you flush the toilet, you may be discarding microscopic warning signs about your health.

But a cunningly simple new device can stop that vital information from "going to waste."

Brigham Young University chemist Adam Woolley and his students made a device that can detect markers of kidney disease and prostate cancer in a few minutes. All you have to do is drop a sample into a tiny tube and see how far it goes.

Lack of transcription factor FoxO1 triggers pulmonary hypertension

This news release is available in German.

Pulmonary hypertension is characterised by uncontrolled division of cells in the blood vessel walls. As a result, the vessel walls become increasingly thick.

Study documents millions in unused medical supplies in US operating rooms each year

A Johns Hopkins research team reports that major hospitals across the U.S. collectively throw away at least $15 million a year in unused operating room surgical supplies that could be salvaged and used to ease critical shortages, improve surgical care and boost public health in developing countries.

Persuading doctors to quickly adopt new treatments

  • Influencers trump belief that doctors adopt a new therapy by watching others use it
  • Surprisingly long road from FDA approval to use by doctors
  • New technology is like an influential colleague -- opinionated but not too bossy
  • Doctors need to be reminded every five to seven days

CHICAGO --- Doctors are more likely to try a new therapy when they are persuaded to do so by an influential colleague, reports a new Northwestern University study whose findings on adopting innovations also have relevance for business, education and research.

Study finds knowledge poor about stroke in Uganda

CLEVELAND -- A study published in the journal International Scholarly Research Notices (ISRN) Stroke found that overall knowledge about stroke in Uganda was poor, although knowing what to do for a stroke – go to the hospital – was good.

New RCT: KoACT® beats calcium and vitamin D for optimal bone strength

ity of Industry, CA – October 28, 2014 – A new randomized controlled trial (RCT) of post-menopausal women demonstrates that a proprietary blend of collagen and calcium, KoACT®, was far superior to calcium and vitamin D in slowing down the leaching of calcium from bones and rebuilding new bone strength. An Abstract of the article appears on PubMed at: http://www.ncbi.nlm.nih.gov/pubmed/25314004, ahead of print in The Journal of Medicinal Food.

GW researcher adapting breakthrough technologies to combat parasitic worm infections

WASHINGTON (Oct. 27, 2014) — Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year.

Ultrasound guides tongue to pronounce 'r' sounds

Using ultrasound technology to visualize the tongue's shape and movement can help children with difficulty pronouncing "r" sounds, according to a small study by NYU's Steinhardt School of Culture, Education, and Human Development and Montclair State University.

The ultrasound intervention was effective when individuals were allowed to make different shapes with their tongue in order to produce the "r" sound, rather than being instructed to make a specific shape. The findings appear online in the Journal of Speech, Language, and Hearing Research.

Slowing the biological clock

Difficulty in conceiving a child is a major challenge for one in seven heterosexual couples in America, especially for those over the age of 35. Now a new discovery by researchers at Tel Aviv University and Chaim Sheba Medical Center at Tel Hashomer could boost the chances of conception in women undergoing in vitro fertilization (IVF) treatments.