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Newborn screening expansion offers early diagnosis and treatment to infants with SCID

WORCESTER, MA – Using population-based screening outcomes of approximately 3 million infants, a team of scientists across 14 states, including four researchers at the University of Massachusetts Medical School, have shown that newborn screening for severe combined immunodeficiency (SCID) can be successfully implemented across public health newborn screening programs. Data from 11 newborn screening programs published in the Aug.

Turning waste from rice, parsley and other foods into biodegradable plastic

Your chairs, synthetic rugs and plastic bags could one day be made out of cocoa, rice and vegetable waste rather than petroleum, scientists are now reporting. The novel process they developed and their results, which could help the world deal with its agricultural and plastic waste problems, appear in the ACS journal Macromolecules.

Teen sleeplessness piles on risk for obesity

Teenagers who don't get enough sleep may wake up to worse consequences than nodding off during chemistry class. According to new research, risk of being obese by age 21 was 20 percent higher among 16-year-olds who got less than six hours of sleep a night, compared with their peers who slumbered more than eight hours. (The Centers for Disease Control and Prevention recommends nine to ten hours of sleep for teenagers.)

Novel gene predicts both breast cancer relapse and response to chemotherapy

Singapore—Scientists have made it easier to predict both breast cancer relapses and responses to chemotherapy, through the identification of a unique gene. The newly found marker could help doctors classify each breast cancer patient and customise a treatment regimen that is more effective. The discovery was a collaborative effort by scientists from A*STAR's Institute of Molecular and Cell Biology (IMCB), and the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS).

The channel that relaxes DNA

This is a model DNA chain inside a nanochannel that is 100nm wide.The spontaneous dynamical evolution of the DNA is accompanied by frequent knotting and entanglement at the chain ends.

(Photo Credit: SISSA)

Test reliably detects inherited immune deficiency in newborns

A newborn screening test for severe combined immunodeficiency (SCID) reliably identifies infants with this life-threatening inherited condition, leading to prompt treatment and high survival rates, according to a study supported by the National Institutes of Health. Researchers led by Jennifer Puck, M.D., of the University of California, San Francisco, also found that SCID affects approximately 1 in 58,000 newborns, indicating that the disorder is less rare than previously thought.

Mums trust mums on the net: Australian study

Facebook groups for mothers are overtaking the traditional mums-and-bubs and playgroup environments as a source of trusted advice, and offers a largely untapped marketing tool for businesses wanting to sell their products, an Australian study has found.

QUT educationalist Dr Rebecca English and marketing expert Dr Raechel Johns from the University of Canberra said word-of-mouth in mothers' groups and communities had fast become a major influence in mothers' buying habits.

Treating pain by blocking the 'chili-pepper receptor'

Biting into a chili pepper causes a burning spiciness that is irresistible to some, but intolerable to others. Scientists exploring the chili pepper's effect are using their findings to develop a new drug candidate for many kinds of pain, which can be caused by inflammation or other problems. They reported their progress on the compound, which is being tested in clinical trials, in ACS' Journal of Medicinal Chemistry.

The changing landscape of religion

Religion is a key factor in demography, important for projections of future population growth as well as for other social indicators. A new journal, Yearbook of International Religious Demography, is the first to bring a quantitative demographic focus to the study of religion. The journal is co-edited by IIASA researcher Vegard Skirbekk, an expert in the field of religious demography. The first edition of the journal includes three studies by IIASA researchers:

Vienna: Growing diversity in religion and ethnicity

Vanderbilt researchers find that coronary arteries hold heart-regenerating cells

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.

The findings, published recently in Cell Reports, offer insights into how the heart maintains itself and could lead to new strategies for repairing the heart when it fails after a heart attack.

The heart has long been considered to be an organ without regenerative potential, said Antonis Hatzopoulos, Ph.D., associate professor of Medicine and Cell and Developmental Biology.

CU Denver researcher shows economic disparities impact infant health

DENVER (August 20, 2014) – Women who are poor experience higher cortisol levels in pregnancy and give birth to infants with elevated levels of the stress hormone, putting them at greater risk for serious disease later in life, according to a new research from the University of Colorado Denver.

The study, published online recently in the American Journal of Human Biology, is the first to measure cortisol in infants and relate it directly to the socioeconomic status of their mothers during pregnancy.

Scientists show type-1 and type-2 diabetes are caused by same underlying mechanism

Work by scientists at the Universities of Manchester and Auckland suggest that both major forms of diabetes are the result of the same mechanism.

The findings, published today in the FASEB Journal (20 August), provide compelling evidence that juvenile-onset or type-1 diabetes and type-2 diabetes are both caused by the formation of toxic clumps of a hormone called amylin.

Review of clinical treatment of bronchiolitis in infants reveals over-reliance on one test

(Boston) – An editorial published in this week's JAMA highlights the importance of physicians using all available clinical assessment tools when considering how to treat patients. Written by Robert Vinci, MD, chief of pediatrics at Boston Medical Center and chair of pediatrics at Boston University School of Medicine and Howard Bauchner, MD, editor-in-chief of JAMA, the editorial examines results of a study published in the same issue of the journal as an example of how doctors can often over-emphasize certain types of data.

Gender differences in experiencing orgasms

Among single adults in the U.S., women, regardless of sexual orientation, have less predictable, more varied orgasm experiences than do men, new research indicates. The study revealed that men experience orgasm during sexual activity with a familiar partner 85% of the time on average, compared with 63% of the time for women.

Rates of heart disease and stroke continue to decline in Europe

Deaths from heart disease and stroke are declining overall in Europe, but at differing rates, according to research, published online today (Wednesday) in the European Heart Journal [1].