Body

Blood pressure changes are age-related

The main causes of increases in blood pressure over a lifetime are modifiable and could be targeted to help prevent cardiovascular disease: although high blood pressure sometimes has no obvious symptoms, this condition, which affects about a third of the adult UK and US populations, can lead to life-threatening heart attacks and stroke, so reducing blood pressure is very important for health.

New HIV incidence assays could transform AIDS prevention efforts

HIV prevention activities aiming to reduce incidence could be targeted more effectively and efficiently if a quick, easy, valid, and precise method of estimating incidence in populations were available. These are the conclusions of a group of international experts convened to discuss the challenges and progress in the field, with the aim of stimulating new investment in technologies for identifying recent HIV infections.

Migration interception practices are a major threat to health

In the fifth article of a six-part PLoS Medicine series on migration & health, Zachary Steel from the University of New South Wales in Sydney, Australia and colleagues discuss the health risks associated with "interception strategies" that are used by governments to control and order international migration, especially in terms of halting the movement of irregular migrants, including asylum seekers.

New light shed on cell division

Genes control everything from eye color to disease susceptibility, and inheritance - the passing of the genes from generation to generation after they have been duplicated - depends on centromeres. Located in the little pinched waist of each chromosome, centromeres control the movements that separate sister chromosomes when cells divide ensuring that each daughter cell inherits a complete copy of each chromosome. It has long been known that centromeres are not formed solely from DNA; rather, centromere proteins (CENPs) facilitate the assembly of a centromere on each chromosome.

Van Andel Research Institute finding is potential predictor of deadly cancer common in Asia

Grand Rapids, Mich. (June 14, 2011) – In a study recently published in Cancer Research, Van Andel Research Institute (VARI) researchers found a protein that could help predict the spread of the head and neck cancer nasopharyngeal carcinoma (NPC); this protein could also serve as part of a treatment strategy to stop the spread of the disease.

Restoring trust vital in public acceptance of the use of residual newborn screening specimens

ANN ARBOR, Mich. – Government guidelines published today on the use of dried blood spots collected during mandatory newborn screening underemphasize the importance of getting the public on board with the practice, according to University of Michigan researcher.

Salivating over wheat plants may net Hessian flies big meal or death

WEST LAFAYETTE, Ind. - The interaction between a Hessian fly's saliva and the wheat plant it is attacking may be the key to whether the pest eats like a king or dies like a starving pauper, according to a study done at Purdue University.

Prostate cancer gets around hormone therapy by activating a survival cell signaling pathway

Cancer is crafty. When one avenue driving its growth is blocked by drugs targeting that path, the malignancy often creates a detour, finding an alternative route to get around the roadblock.

Note to dads: Good parenting makes a difference

Father's Day this Sunday is a chance to recognize dads for putting up with all manner of nonsense that kids manage to cook up on the way to adulthood.

But a new study by researchers at the University of Arizona shows just how important dad's job as a role model actually is.

The study, "Impact of Fathers on Risky Sexual Behavior in Daughters: A Genetically and Environmentally Controlled Sibling Study," is due to be published in the journal Development and Psychopathology.

Unique gene combinations control tropical maize response to day lengths

MADISON, WI, JUNE 14, 2011 - Tropical maize proves to be a valuable genetic resource, containing genetics not found in USA Corn Belt maize. Most tropical maize varieties respond to the long summer day lengths that occur in U.S. growing regions by flowering late. This delayed flowering response results in poor yields, effectively trapping the useful genes and hindering their incorporation into maize hybrids adapted to the most productive corn growing regions.

Scientists image beginning stages of ovarian cancer growth with time-lapse technique

PHILADELPHIA — Scientists at Harvard University have created a laboratory model using time-lapse video microscopic technology that allows observation of early stages of ovarian cancer metastasis.

"We were able to observe key molecular mechanisms that are necessary for the force-dependent processes associated with metastasis," said Joan Brugge, Ph.D., professor and chair of cell biology at Harvard University.

Ovarian cancer cells bully their way through tissue

BOSTON, Mass. (June 14, 2011) — A team led by Joan Brugge, the Louise Foote Pfeiffer Professor of Cell Biology at Harvard Medical School, recently shed light on how ovarian cancer spreads. In a paper published in the July edition of the journal Cancer Discovery, the newest journal of the American Association for Cancer Research, Brugge and colleagues found that ovarian cancer cells act like bullies, using brute force to plow their way through tissue and colonize additional organs.

Stress may lead to better bird parenting

Birds with high levels of stress hormones have the highest mating success and offer better parental care to their brood, according to new biology research at Queen's University.

"Having high levels of glucocorticoid or stress hormone is often thought to indicate an individual in poor condition who has a low level of mating success. However, our research indicates that tree swallows with the highest levels of stress hormone have the highest reproductive success," says Frances Bonier (Biology) who investigates the way animals cope with challenges in their environment.

Mount Sinai researchers find potential therapeutic target for controlling obesity

A new study from Mount Sinai School of Medicine has found that a cellular signaling pathway governs the differentiation of cells into fat tissue or smooth muscle, which lines the vascular system. Engaging this signaling pathway and its capacity to govern cell differentiation has important implications in preventing obesity and cardiovascular disease. The study is published in the June issue of Developmental Cell.

New research provides clues on why hair turns gray

A new study by researchers at NYU Langone Medical Center has shown that, for the first time, Wnt signaling, already known to control many biological processes, between hair follicles and melanocyte stem cells can dictate hair pigmentation. The study was published in the June 11, 2011 issue of the journal Cell.