Body

In colorectal surgery, risk for blood clots appears higher with open method versus laparoscopy

The risk of developing venous thromboembolism (VTE) may be nearly twice as high for patients undergoing open surgery for colorectal problems, versus those undergoing laparoscopic colorectal (LC) resections, according to a report in the June issue of Archives of Surgery, one of the JAMA/Archives journals.

In general, hospitals deliver appropriate surgical care to cancer patients with Medicare

Most hospitals follow established practice guidelines for surgery involving Medicare beneficiaries with cancer, but in some cases their practice patterns diverge from the guidelines, according to a report published Online First today by Archives of Surgery, one of the JAMA/Archives journals.

Analysis of studies evaluates tonsillectomy techniques

A review of tonsillectomy-technique studies found that some new methods have advantages over traditional methods, but others are equivalent, according to a report in the June issue of Archives of Otolaryngology–Head and Neck Surgery, one of the JAMA/Archives journals.

Intranasal corticosteroid treatment appears beneficial for children with obstructive sleep apnea

Using a fluticasone furoate nasal spray for treatment of obstructive sleep apnea in children appears to reduce production of certain inflammatory cell proteins that may play a role in development of obstructive sleep apnea, according to a report in the June issue of Archives of Otolaryngology – Head & Neck Surgery, one of the JAMA/Archives journals.

Study compares 2 types of botulinum toxin for cosmetic use

Not all varieties of botulinum toxin seem to be equally effective in reducing crow's feet wrinkles, according to a report published Online First today by Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.

Bacteria develop restraint for survival in a rock-paper-scissors community

It is a common perception that bigger, stronger, faster organisms have a distinct advantage for long-term survival when competing with other organisms in a given community.

But new research from the University of Washington shows that in some structured communities, organisms increase their chances of survival if they evolve some level of restraint that allows competitors to survive as well, a sort of "survival of the weakest."

Discoveries in mitochondria open new field of cancer research

Richmond, Va. (June 20, 2011) – Researchers at Virginia Commonwealth University Massey Cancer Center have revealed novel mechanisms in mitochondria that have implications for cancer as well as many other age-related diseases such as Parkinson's disease, heart disease and hypertension. This discovery has pioneered the formation of a whole new field within epigenetics research ripe with possibilities of developing future gene therapies to treat cancer and age-associated diseases.

Acute Hepatitis A evades immune system more effectively than chronic cousin

Chapel Hill, NC – Ongoing research into the problem of how Hepatitis C becomes a chronic disease has uncovered a deeper mystery about its sister strain, Hepatitis A.

Hepatitis C is a continuing public health problem, which is difficult to measure because symptoms occur months to years after infection. The World Health Organization estimates as many as 2 to 4 million people in the United States may have chronic Hepatitis C, and most do not know they are infected. More than a third of those who are long-term carriers may develop chronic liver disease or liver cancer.

'Smart materials' that make proteins form crystals to boost research into new drugs

Scientists have developed a new method to make proteins form crystals using 'smart materials' that remember the shape and characteristics of the molecule. The technique, reported today in Proceedings of the National Academy of Sciences, should assist research into new medicines by helping scientists work out the structure of drug targets.

Penn researchers link fastest sea-level rise in 2 millennia to increasing temperatures

PHILADELPHIA — An international research team including University of Pennsylvania scientists has shown that the rate of sea-level rise along the U.S. Atlantic coast is greater now than at any time in the past 2,000 years and that there is a consistent link between changes in global mean surface temperature and sea level.

Nanoparticles disguised as red blood cells will deliver cancer-fighting drugs

Researchers at the University of California, San Diego have developed a novel method of disguising nanoparticles as red blood cells, which will enable them to evade the body's immune system and deliver cancer-fighting drugs straight to a tumor. Their research will be published next week in the online Early Edition of the Proceedings of the National Academy of Sciences.

New study reveals how the immune system responds to hepatitis A virus

A surprising finding in a study comparing hepatitis C virus (HCV) with hepatitis A virus (HAV) infections in chimpanzees by a team that includes scientists from the Texas Biomedical Research Institute sheds new light on the nature of the body's immune response to these viruses.

Signaling pathway is 'executive software' of airway stem cells

DURHAM, NC – Researchers at Duke University Medical Center have found out how mouse basal cells that line airways "decide" to become one of two types of cells that assist in airway-clearing duties. The findings could help provide new therapies for either blocked or thinned airways.

The myth of the 'queen bee': Work and sexism

Female bosses sometimes have a reputation for not being very nice. Some display what's called "queen bee" behavior, distancing themselves from other women and refusing to help other women as they rise through the ranks. Now, a new study, which will be published in an upcoming issue of Psychological Science, a journal of the Association for Psychological Science, concludes that it's wrong to blame the woman for this behavior; instead, blame the sexist environment.

Discovery of parathyroid glow promises to reduce endocrine surgery risk

The parathyroid glands – four small organs the size of grains of rice located at the back of the throat – glow with a natural fluorescence in the near infrared region of the spectrum.

This unique fluorescent signature was discovered by a team of biomedical engineers and endocrine surgeons at Vanderbilt University, who have used it as the basis of a simple and reliable optical detector that can positively identify the parathyroid glands during endocrine surgery.