Body

Researchers at Oregon Health & Science University discover MS-like disease in monkeys

Portland, Ore. — Researchers at Oregon Health & Science University have discovered a naturally occurring disease in monkeys that is very much like multiple sclerosis in humans — a discovery that could have a major impact on efforts to understand the cause of multiple sclerosis.

International team explores the stigma surrounding abortion

An international team of researchers says abortion stigma is under-researched, under theorized and over emphasized in one category: women who've had abortions. As a result, they're launching a new direction into research that explores the social stigma surrounding abortion.

Study shows climate change makes some chemicals more toxic to aquatic life

Some areas of the southern United States are suffering from the longest dry spell since 1887 and a new Baylor University study shows that could prove problematic for aquatic organisms.

Van Andel Research Institute finding could lead to reduced side effects in anti-cancer antibiotics

Grand Rapids, Mich. (June 28, 2011) – Most of us have had a doctor prescribe an antibiotic for a stubborn bacterial infection, or for a cut that gets infected. However, prescribing an antibiotic to fight cancer? In fact, anti-cancer antibiotics have been used since the 1950s to successfully treat several forms of cancer, but often the side effects limit the duration they can be given to a patient.

Patients treated with sunitinib and sorafenib respond to flu vaccine

PHILADELPHIA — Patients treated with sunitinib and sorafenib responded to the flu vaccine, which suggests the agents do not damage the immune system as much as previously feared, according to a study in Clinical Cancer Research, a journal of the American Association for Cancer Research.

Keith Flaherty, M.D., director of developmental therapeutics at the Massachusetts General Hospital and a senior editor of Clinical Cancer Research, said the findings have broad implications beyond questions of patient management.

Rockin' tortoises: A 150-year-old new species

A team of researchers investigated a desert tortoise from the Southwest USA and northwestern Mexico. What was thought to be a simple problem in species identification turned out to be a very complex matter. Their investigations required forensic genetics and several other methods. In the end, they found it necessary to describe a new species. More than that, the discovery has very important implications for conservation and the development of the deserts of southern California.

Insight into plant behavior could aid quest for efficient biofuels

Tiny seawater algae could hold the key to crops as a source of fuel and plants that can adapt to changing climates.

Researchers at the University of Edinburgh have found that the tiny organism has developed coping mechanisms for when its main food source is in short supply.

Understanding these processes will help scientists develop crops that can survive when nutrients are scarce and to grow high-yield plants for use as biofuels.

New study finds rise in global malaria R&D funds leads to largest ever pipeline of new products

LONDON (28 JUNE 2011)—A new analysis of progress in the global fight against malaria finds a four-fold increase in annual funding for malaria research and development (R&D) in just 16 years—increasing from US$121 million in 1993 to US$612 million in 2009, with a particularly rapid increase since 2004. The funding has generated the strongest pipeline of malaria control and prevention products in history.

Fidgeting your way to fitness

Walking to the photocopier and fidgeting at your desk are contributing more to your cardiorespiratory fitness than you might think.

Researchers have found that both the duration and intensity of incidental physical activities (IPA) are associated with cardiorespiratory fitness. The intensity of the activity seems to be particularly important, with a cumulative 30-minute increase in moderate physical activity throughout the day offering significant benefits for fitness and long-term health.

Scientists measure body temperature of dinosaurs for the first time

Were dinosaurs slow and lumbering, or quick and agile?

It depends largely on whether they were cold- or warm-blooded.

When dinosaurs were first discovered in the mid-19th century, paleontologists thought they were plodding beasts that relied on their environment to keep warm, like modern-day reptiles.

But research during the last few decades suggests that they were faster creatures, nimble like the velociraptors or T. rex depicted in the movie Jurassic Park, requiring warmer, regulated body temperatures.

P7 protein resistance mutations identified; represent drug targets for hepatitis C virus

British researchers have identified specific resistance mutations for two classes of p7 inhibitor, which may explain their lack of effectiveness in clinical trials combined with current standard of care. Study results support the role of p7 inhibitor combinations as potential components of future HCV-specific therapies and are available in the July issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases.

To walk or not to walk? That is the question

Montreal, June 28, 2011 —Canadians aren't the only people concerned with weather, eh? A new study from McGill and Concordia universities observed pedestrians in nine cities around the world and found people are less likely to walk when temperatures dip below zero, when there's too much rain or too much snow. Published in the journal Environment and Behavior, the study was conducted over 170 days from late fall to early summer.

Gene variant increases fatty liver risk and fibrosis progression

New research confirms that a variant on the patatin-like phospholipase-3 (PNPLA3) gene increases risk of steatosis and fibrosis progression in patients with chronic hepatitis C virus (HCV). The PNPLA3 single nucleotide polymorphism (SNP) rs 738409 may represent an important genetic predictor and potential therapeutic target in chronic HCV liver damage. Study details are published in the July issue of Hepatology, a peer-reviewed journal of the American Association for the Study of Liver Diseases.

Tropical birds return to harvested rainforest areas in Brazil

Bird species in rainforest fragments in Brazil that were isolated by deforestation disappeared then reappeared over a quarter-century, according to research results published today in the journal PLoS ONE.

Scientists thought many of the birds had gone extinct.

The research was funded by the National Science Foundation (NSF), and conducted in cooperation with Projeto Dinâmica Biológica de Fragmentos Florestais, Instituto Nacional de Pesquisas da Amazônia and the Smithsonian Tropical Research Institute in Manaus, Brazil.

Will new drugs block hepatitis C virus in its tracks?

Targeted multi-drug treatments for hepatitis C patients that could stop the virus in its tracks have come a step closer, thanks to researchers at the University of Leeds, UK.

The study by Dr Stephen Griffin and colleagues, published in the journal Hepatology, reveals how two prototype small molecule drugs, known as p7 inhibitors, can each attack different parts of the hepatitis C virus. Their findings suggest that p7 inhibitors could be a powerful way of suppressing hepatitis C, when used together with the latest generation of 'direct-acting' drugs.