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Researchers shed new light on the genetic history of the European beaver

An international team of scientists has used detailed analysis of ancient and modern DNA to show that the distribution and lack of genetic diversity among modern European beavers is due largely to human hunting.

The research, which was led by University of York researcher Professor Michi Hofreiter, provides important new insights into the genetic history of the Eurasian beaver Castor fiber. Crucially, it shows the European beaver has been strongly affected by expanding human populations for many thousands of years.

Beauty & bacteria: Slim, attractive men have less nasal bacteria than heavy men

Do attractive traits tell us anything about a person's reproductive health? New research in the American Journal of Human Biology reveals a link between Body Mass Index (BMI) and the amount of bacteria colonizing noses. The results show that heavier men harbor more potentially pathogenic species of bacteria in their nose, compared with slimmer, more traditionally attractive men.

Infected Tasmanian devils reveal how cancer cells evolve in response to humans

Tasmanian Devil Facial Tumour Disease (DFTD) has ravaged the world's largest carnivorous marsupial since it emerged in 1996, resulting in a population decline of over 90%. Conservation work to defeat the disease has including removing infected individuals from the population and new research in Evolutionary Applications explains how this gives us a unique opportunity to understand how human selection alters the evolution of cancerous cells.

Guam mantas have moon parties

University of Guam graduate student Julie Hartup has observed previously unknown manta behavior.

Environmental issues examined through cohesive efforts

CHICAGO – Solving crucial environmental issues such as global warming and water supply involves managing competing interests, uncertainty and risk, and this is best done through meaningful collaboration in a neutral environment.

Arizona State University Barrett Honors College Lecturer John N. Parker discussed the ways in which scientists, stakeholders and policy makers can communicate effectively by coming together through boundary organizations at the annual meeting of the American Association for the Advancement of Science in Chicago.

NUS researchers make new discovery of protein as a promising target for treatment of ATC

Anaplastic thyroid carcinoma (ATC) is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore (NUS) have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC.

Researchers identify new way to control stone fruit disease

Researchers at the University of Kent and East Malling Research have identified a new way of controlling a fungal disease that can have a devastating impact on the UK's valuable cherry and plum crops.

Brown rot disease – caused by the agent Monilinia laxa – attacks stone fruit as well as causing blossom wilt and twig canker. Traditionally, this has been controlled through the use of fungicide treatments, but in some cases these are now becoming ineffective.

In search of lost genes

How do new genes arise? Current research shows that so-called "orphan genes" may appear as if by magic as a result of mutations in segments of DNA that previously had no function. Orphan genes were first discovered in the fruit fly but are found in all organisms, including man. Strikingly, up to 30 per cent of the total number of genes in an organism may be orphans and these genes may rapidly acquire functions. Scientists from the Institute of Population Genetics of the University of Veterinary Medicine, Vienna (Vetmeduni) have now investigated the fate of orphan genes.

Scientists chip away at the mystery of what lives in our mouths

COLUMBUS, Ohio – Scientists have pieced together sections of DNA from 12 individual cells to sequence the genome of a bacterium known to live in healthy human mouths.

With this new data about a part of the body considered "biological dark matter," the researchers were able to reinforce a theory that genes in a closely related bacterium could be culprits in its ability to cause severe gum disease.

ASU professor explores the ethics of scientific research and why they matter

CHICAGO — Discovery and innovation are important to science, but how are they connected to each other, and how can they be fostered to benefit the wider public? Jason Robert, the Lincoln Chair in Ethics and Dean's Distinguished Professor of Life Sciences at Arizona State University discussed that question today (Feb. 16) at the annual meeting of the American Association for the Advancement of Science in Chicago.

Malaria vaccine development paves way for protective therapy

Scientists have made a significant contribution towards the development of a vaccine to prevent malaria.

Researchers have tested a preliminary form of a vaccine against the disease, which is spread by the bite of the mosquito and kills more than 600,000 people each year.

Until now, developing malaria vaccines has been challenging. A vaccine must incorporate key proteins from the malaria parasites, which will trigger production of antibodies by the immune system. These proteins have a complex, intricate structure that is hard to reproduce.

Crowdsourced testers prefer new cyber search method

Computer scientists at Case Western Reserve University have developed a new tool to search and fetch electronic files that saves users time by more quickly identifying and retrieving the most relevant information on their computers and hand-held devices.

Anonymous testers recruited through crowdsourcing preferred the new search tool nearly two-to-one over a keyword-based lookup interface and the most commonly available lookup search interface using Google.

'It takes a village' -- Community-based methods for improving maternal and newborn health

A series of studies are published in a special supplement that presents results of the Maternal and Newborn Health in Ethiopia Partnership—a three-year pilot program funded by the Bill & Melinda Gates Foundation with the goal of improving the health of Ethiopian mothers and their newborns. This special issue of the Journal of Midwifery & Women's Health is published by Wiley on behalf of the American College of Nurse-Midwives.

Mitosis mystery solved as role of key protein is confirmed

Researchers from Warwick Medical School have discovered the key role of a protein in shutting down endocytosis during mitosis, answering a question that has evaded scientists for half a century.

The study, published today in the journal eLife, is the first to outline the role of actin, a protein, in shutting down clathrin-dependent endocytosis during mitosis.

Annals of Internal Medicine tip sheet for Feb. 18, 2014

1. Aortic valve replacement improves function but may not improve quality of life