Body

Bisphenol A exposure in pregnant mice permanently changes DNA of offspring

Exposure during pregnancy to the chemical bisphenol A, or BPA, found in many common plastic household items, is known to cause a fertility defect in the mother's offspring in animal studies, and now researchers have found how the defect occurs. The results of the new study will be presented Saturday at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

Bisphenol A exposure increases risk of abnormal heart rhythms in female rodents

The chemical bisphenol A, commonly found in many plastic household items, has been linked to yet another health problem in animals—an increased frequency of arrhythmias, or heartbeat irregularities, a new study found. The results, seen only in females, will be presented Saturday at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

Our exposure to controversial chemical may be greater than dose considered safe

People are likely being exposed to the commonly used chemical bisphenol A (BPA) at levels much higher than the recommended safe daily dose, according to a new study in monkeys. The results will be presented Thursday at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

Availability of diagnostic tests drive success in hospitalist-run short-stay units

Illinois, USA – June 10, 2009 – The most important factors for a successful stay in hospital short-stay units (SSUs) are the types of diagnostic tests performed and whether or not specialty consultations are needed. When hospitalists staff these units, they can ensure that only patients who need readily accessible services are admitted. These are the findings of a study published today in the Journal of Hospital Medicine.

German Research Minister Schavan: 'Rapid knowledge transfer can safe lives'

Postpartum anxiety delays puberty in offspring

Hormonal changes early in pregnancy cause maternal postpartum anxiety and behavior changes that can lead to a delayed onset of puberty in both birth and adoptive daughters, according to a new study conducted in mice. The results will be presented Wednesday at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

Women have an increased rate of anxiety during pregnancy and for 2 years after giving birth, said the study's lead author, Caroline Larsen, PhD, a postdoctoral fellow at the University of Otago in Dunedin, New Zealand.

Hormone therapy may confer more aggressive properties to prostate tumors

Hormone therapy is often given to patients with advanced prostate cancer. While it is true that the treatment prevents growth of the tumour, it also changes its properties. Some of these changes may result in the tumour becoming more aggressive and more liable to form metastases. This is one of the conclusion of a thesis presented at the Sahlgrenska Academy, University of Gothenburg, Sweden.

Tribble 3 can induce non-alcoholic fatty liver disease?

Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. Recent research has found that the expression of hepatic TRB3 increased in a rat model of diabetes. TRB3 could block the insulin signaling pathway through inhibiting Akt activation, which contributes to insulin resistance.

A potential treatment for gastric motility disorders

GES or pacing has been under investigation as a potential therapy for gastrointestinal motility disorders. Conventionally, GES is performed using a single pair of electrodes or single-channel GES. However, few studies have investigated the effects of two-channel GES with trains of pulses on gastric motility, such as gastric slow waves and gastric emptying.

Revised Vienna Classification for diagnosing colorectal epithelial neoplasias

Considerable discrepancies have been reported between diagnoses of colorectal epithelial neoplastic lesions made by Western and Japanese pathologists from endoscopic cold biopsies and resected specimens of the same lesions

Endoscopic ultrasonography can differentiate neoplastic from

Although most gallbladder (GB) polyps are benign, some early carcinomas of the GB share the same appearance as benign polyps. Currently, GB polyps larger than 1 cm should be surgically removed because of the increased risk of malignancy. On the other hand, patients with smaller polyps usually require repeated US and follow-up. Distinguishing among non-neoplastic, neoplastic, and potentially malignant lesions is a major diagnostic dilemma, and the therapeutic options for these lesions remain controversial.

Beetle shell inspires brilliant white paper

An obscure species of beetle has shown how brilliant white paper could be produced in a completely new way. A team from Imerys Minerals Ltd. and the University of Exeter has taken inspiration from the shell of the Cyphochilus beetle to understand how to produce a new kind of white coating for paper.

Genetic pathway responsible for link between body clock disturbance and worsening arthritis

Copenhagen, Denmark, Wednesday 10 June 2009: The genes that regulate human circadian rhythm, or 'the body clock', are significantly disturbed in individuals with arthritis, according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rheumatism in Copenhagen, Denmark. Notably, a specific genetic pathway has been identified as responsible for interactions between the genes that regulate the body clock and those that may worsen symptoms of arthritis.

First-degree relatives of patients with bicuspid aortic valve should be screened

Bicuspid Aortic Valve (BAV), a condition in which patients' aortic valves have just two leaflets instead of the normal three, is the most common cardiac anomaly, affecting up to two percent of the general population. The defect can result in calcification deposits on the heart valve, leakage of the valve and may results in a feeling of tightness in the chest as well as shortness of breath. The condition is easily diagnosed; often physicians can hear a "click" or a murmur when they listen to a BAV patient's heart with a stethoscope.

Hormone therapy plus physical activity reduce belly fat, body fat percentage after menopause

Older women who take hormone therapy to relieve menopausal symptoms may get the added benefit of reduced body fat if they are physically active, according to a new study. The results were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.