Body

No evidence that drug used for preventing life-threatening bleeding in women during labor works

There is insufficient evidence for the effectiveness of a drug that is being used increasingly to prevent life-threatening bleeding in women after giving birth in community settings in low income countries, according to a review of all the available research published today (Monday) in the Journal of the Royal Society of Medicine. [1]

Canine tail chasing resembles human obsessive compulsive disorders

The genetics research group, based at the University of Helsinki and the Folkhälsan Research Center and led by Professor Hannes Lohi, has in collaboration with an international group of researchers investigated the characteristics and environmental factors associated with compulsive tail chasing in dogs.

Molecular code cracked

The code determines the recognition of RNA molecules by a superfamily of RNA-binding proteins called pentatricopeptide repeat (PPR) proteins.

When a gene is switched on, it is copied into RNA. This RNA is then used to make proteins that are required by the organism for all of its vital functions. If a gene is defective, its RNA copy and the proteins made from this will also be defective. This forms the basis of many terrible genetic disorders in humans.

Evidence that new biomimetic controlled-release capsules may help in gum disease

PHILADELPHIA, Aug. 20, 2012 — Scientists are trying to open a new front in the battle against gum disease, the leading cause of tooth loss in adults and sometimes termed the most serious oral health problem of the 21st century. They described another treatment approach for the condition in a report here today at the 244th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society.

The Innocence Project: Chemistry helping innocent people proven guilty

PHILADELPHIA, Aug. 20, 2012 — Should Lady Justice, that centuries-old personification of truth and fairness in the legal system, cast off her ancient Roman robe, sword and scales and instead embrace 21st century symbols of justice meted out objectively without fear or favor? A scientist's laboratory jacket, perhaps? And a spiral strand of the genetic material DNA?

Secondhand smoke impairs vital cough reflex in kids

PHILADELPHIA (August 20, 2012) – New research from the Monell Center reveals that exposure to secondhand smoke decreases sensitivity to cough-eliciting respiratory irritants in otherwise healthy children and adolescents. The findings may help to explain why children of smokers are more likely to develop pneumonia, bronchitis and other diseases and also are more likely to experiment with smoking during adolescence.

The wasp that never cries wolf

European paper wasps (Polistes dominula) advertise the size of their poison glands to potential predators, finds a new study published in BioMed Central's open access journal Frontiers in Zoology. The brighter the colour, the larger the poison gland.

Meddling with male malaria mosquito 'mating plug' to control an epidemic

PHILADELPHIA, Aug. 19, 2012 — Using information about the unique mating practices of the male malaria mosquito ― which, unlike any other insect, inserts a plug to seal its sperm inside the female ― scientists are zeroing in on a birth-control drug for Anopheles mosquitoes, deadly carriers of the disease that threatens 3 billion people, has infected more than 215 million and kills 655,000 annually.

'DNA wires' could help physicians diagnose disease

PHILADELPHIA, Aug. 19, 2012 — In a discovery that defies the popular meaning of the word "wire," scientists have found that Mother Nature uses DNA as a wire to detect the constantly occurring genetic damage and mistakes that ― if left unrepaired ― can result in diseases like cancer and underpin the physical and mental decline of aging.

Inspired by genetics, chemistry finally takes hold of its own code

Nature proves every day that it is both complex and efficient. Organic chemists are envious of it; their conventional tools confine them to simpler achievements. Thanks to the work of professor Stefan Matile's team from the University of Geneva, these limitations could become a thing of the past. His publication in the Nature Chemistry journal indeed offers a new kind of code to chemists, allowing them to access new levels of complexity.

Massachusetts butterflies move north as climate warms

PETERSHAM, Mass. (August 19, 2012)---The authors of a Harvard study published today in Nature Climate Change gathered their data from an unlikely source—the trip accounts of the Massachusetts Butterfly Club. Over the past 19 years, the amateur naturalist group has logged species counts on nearly 20,000 expeditions throughout Massachusetts. Their records fill a crucial gap in the scientific record.

Regulatory science for public health: From functional food to modified-risk tobacco products

19 August 2012: Consumers face a barrage of product claims each day. These claims create consumer expectation of safety and product performance and, assuming they are accurate, facilitate well informed choice. But increased scrutiny of claims, especially where the claim involves potential health outcomes, means that claim substantiation and the science behind it are more important than ever.

Even old frozen embryos yield viable stem cells suitable for biomedical research

Biologists have not given up getting increased access to embryos fior human embryonic stem cell research, still limited under the Obama administration, much like they were under Bush.

A group has found that even after being frozen for 18 years, human embryos can be thawed, grown in the laboratory, and successfully induced to produce human embryonic stem (ES) cells, which represent a valuable resource for drug screening and medical research. Prolonged embryonic cryopreservation as an alternative source of ES cells is the focus of an article in BioResearch Open Access.

Weight-loss surgery results in positive changes in social life, medical conditions

DENVER — New research shows that people who have bariatric surgery to treat obesity report an overall improvement in quality of life issues after surgery, from their relationships to their medical conditions. Arizona State University researchers will present their findings at the 107th Annual Meeting of the American Sociological Association.

Study reveals new molecular target for melanoma treatment

A laboratory study led by UNC medical oncologist Stergios Moschos, MD, demonstrates how a new targeted drug, Elesclomol, blocks oxidative phosphorylation, which appears to play essential role in melanoma that has not been well-understood. Elesclomol (Synta Pharmaceuticals, Lexington, MA) was previously shown to have clinical benefit only in patients with normal serum lactate dehydrogenase (LDH), a laboratory test routinely used to assess activity of disease.