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Duke policy provides ethical foundation for managing drug shortages

DURHAM, N.C. – Hospitals and health systems faced with ongoing shortages of key drugs for cancer and other diseases should develop firm rationing policies based on transparency and fairness, researchers at Duke University Medical Center report.

In a Special Article published online Monday, Sept. 24, 2012 in the Archives of Internal Medicine, the Duke team outlined a policy adopted at Duke Medical Center that established clear-cut rules for apportioning scarce drugs using a hierarchy of clinical need and effectiveness.

Study analyzes variations in antibiotic prescribing among older patients

CHICAGO – A study of Medicare data suggests there was wide variation in antibiotic prescribing for older patients based on geography and the season in which the prescriptions for the medication were written, according to a report published Online First by Archives of Internal Medicine, a JAMA Network publication.

Study links active video gaming with higher energy expenditure in children

CHICAGO – Compared with rest and sedentary video game play, active video gaming with dancing and boxing were associated with increased heart rate, oxygen uptake and energy expenditure in a study of 18 school children in England, according to a report published Online First by Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication.

Feeling guilty versus feeling angry -- who can tell the difference?

When you rear-end the car in front of you at a stoplight, you may feel a mix of different emotions such as anger, anxiety, and guilt. The person whose car you rear-ended may feel angered and frustrated by your carelessness, but it's unlikely that he'll feel much guilt.

Primate study says BPA shortens reproduction span

A Washington State University researcher has found new evidence that the plastic additive BPA can disrupt women's reproductive systems, causing chromosome damage, miscarriages and birth defects.

Life in the extreme

Life in extreme environments – hot acids and heavy metals, for example – can apparently make very similar organisms deal with stress in very different ways, according to new research from North Carolina State University.

Like prostate cancer, bladder cancer patients may benefit from anti-androgen therapy

Bladder cancer patients whose tumors express high levels of the protein CD24 have worse prognoses than patients with lower CD24. A University of Colorado Cancer Center study published today in the Proceedings of the National Academy of Sciences shows that CD24 expression may depend on androgens – and that anti-androgen therapies like those currently used to treat prostate cancer may benefit bladder cancer patients.

First-ever treatment for rare childhood aging disease shows improvement in all trial participants

BOSTON, MA (September 24, 2012) – Results of the first-ever clinical drug trial for children with Progeria, a rare, fatal "rapid-aging" disease, demonstrate the efficacy of a farnesyltransferase inhibitor (FTI), a drug originally developed to treat cancer. The clinical trial results, completed only six years after scientists identified the cause of Progeria, included significant improvements in weight gain, bone structure and, most importantly, the cardiovascular system, according to The Progeria Research Foundation (PRF) and Boston Children's Hospital.

Bone marrow holds secrets for treating colitis and Crohn's

EAST LANSING, Mich. — Michigan State University researchers have unlocked secrets in bone marrow that could lead to improved treatments for colitis and Crohn's disease.

Treating ovarian cancer: New pathways through genetics

Exposing cancer's lethal couriers

Malignant cells that leave a primary tumor, travel the bloodstream and grow out of control in new locations cause the vast majority of cancer deaths. New nanotechnology developed at Case Western Reserve University detects these metastases in mouse models of breast cancer far earlier than current methods, a step toward earlier, life-saving diagnosis and treatment.

A team of scientists, engineers and students across five disciplines built nanochains that home in on metastases before they've grown into new tissues, and, through magnetic resonance imaging, detect their locations.

Breast cancer treatment brings sexual difficulties for postmenopausal women

CLEVELAND, Ohio (September 21, 2012)—Women treated for breast cancer after menopause with aromatase inhibitors have very high levels of sexual difficulties, including low interest, insufficient lubrication, and pain with intercourse. It is an important and underestimated problem, say the authors of a study published online in Menopause, the journal of the North American Menopause Society.

Model confirms active surveillance as viable option for men with low-risk prostate cancer

PHILADELPHIA — A new research model has estimated that the difference in prostate cancer mortality among men with low-risk disease who choose active surveillance versus those who choose immediate treatment with radical prostatectomy is likely to be very modest, possibly as little as two to three months.

Prostate cancer diagnosis and surgery can lead to anxiety, depression and reduced quality of life

JACKSONVILLE, Fla.

New research shows bees decrease their food intake when given compound found in red wine

TEMPE, Ariz. – The idea that drinking red wine may provide health benefits – or possibly even extend your life — is an appealing thought for many people. Now, there may be added attraction. Researchers have found that when given resveratrol, a compound found in red wine, bees consume less food.