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Previous studies that have associated the use of proton pump inhibitors (PPI) – which include popular anti-heartburn medications like Prilosec and Nexium – with an increased incidence of pneumonia may not have found a true cause-and-effect relationship. A study that has been released online by the Journal of General Internal Medicine outlines a strategy for determining when the results of such observational studies may have been distorted by unmeasured factors and then finds that may be the case with the association between PPIs and pneumonia risk.

Reston, Va. (October 1, 2012) – Determining the optimal treatment course and predicting outcomes may get easier in the future for patients with head and neck sqaumous cell carcinomas (HNSCCs) with the use of an investigational imaging agent.

AUGUSTA, Ga. – While it's leveling off, a decade of increased use of sophisticated, expensive, imaging studies has put radiologists and their specialty front and center in health care reform, says the chair of an academic radiology department.

That seemingly dubious distinction gives radiologists the chance to take a leadership role in reducing costs, optimizing utilization and improving patient care, said Dr. James V. Rawson, Chair of the Medical College of Georgia Department of Radiology at Georgia Health Sciences University.

Researchers from the University of Alicante (Spain) have analysed ten brands of cigarettes and found that the concentrations of certain harmful and carcinogenic substances vary significantly from one brand to another. Until now legislation has not covered these compounds and only establishes limits for nicotine, tar and carbon monoxide. Scientists have also developed catalysts to reduce the harmful products in tobacco.

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

The technique, the result of more than 10 years of work, holds promise for a highly specific therapy for the progressively debilitating muscle-weakening human disorder, one that avoids the need for long-term, systemic immunosuppressant drugs that control the disease but may create unwanted side effects.

Advance directives are not widespread among the elderly. This was revealed by a cross-sectional study of 11 German nursing homes performed by Sarah Sommer and her colleagues and presented in the latest issue of Deutsches Ärzteblatt International (Dtsch Arztebl Int 2012; 109(37): 577). In the year 2007, only 11% of the nursing home residents had a personally signed advance directive, while a further 1.4% had a proxy directive, i.e., a document signed not by the resident but by a representative.

The European Drug Initiative on Channels and Transporters (EDICT), which comes to an end this year, focused on membrane proteins. They make up a third of all proteins in every organism and play a key role in many human diseases.

SAN FRANCISCO – October 1, 2012 – People who take statins to reduce their risk of cardiovascular disease are less likely to be diagnosed with the most common form of glaucoma, according to a nationwide study of more than 300,000 patients. A University of Michigan School of Medicine research team, directed by Joshua Stein, MD, MS, found that the risk for glaucoma was reduced by eight percent in patients who took statins continuously for two years, compared with patients who did not take statins.

Water does not forget, says Prof. Boris Koch, a chemist at the Alfred Wegener Institute for Polar and Marine Research in the Helmholtz Association. Irrespective of what happens in the sea: whether the sun shines, algae bloom or a school of dolphins swims through a marine area – everything and everyone leaves biomolecular tracks. With the help of a combination of new techniques, Boris Koch and colleagues can now identify and retrace some of these.

Physicists have directly imaged Landau Levels – the quantum levels that determine electron behaviour in a strong magnetic field – for the first time since they were theoretically conceived of by Nobel prize winner Lev Landau in 1930.

Using scanning tunnelling spectroscopy - a spatially resolved probe that interacts directly with the electrons - scientists at institutions including the University of Warwick and Tohoku University have revealed the internal ring-like structure of these Landau Levels at the surface of a semiconductor.

Oxford, October 1, 2012 - A research team led by Dr. Christos Mantzoros, MD, PhD, at Beth Israel Deaconess Medical Center, Harvard Medical School, has published new findings elucidating the molecular and clinical role of FNDC5/irisin in humans.

Chicago: Women suspected of having breast cancer now have more reasons to be diagnosed with a needle biopsy instead of a traditional open surgical biopsy. Besides avoiding the risks and discomfort of an open surgical procedure, needle biopsies can also lead to improved treatment outcomes according to findings from a new study published in the October issue of the Journal of the American College of Surgeons.

Summers on the Norwegian archipelago of Svalbard are now warmer than at any other time in the last 1,800 years, including during medieval times when parts of the northern hemisphere were as hot as, or hotter, than today, according to a new study in the journal Geology.

BETHESDA, MD – October 1, 2012 – With flu season around the corner, getting a seasonal vaccine might be one of the best ways to prevent people from getting sick. These vaccines only work, however, if their developers have accurately predicted which strains of the virus are likely to be active in the coming season because vaccines must be developed in advance of the upcoming flu season. Recently, a team of scientists from Germany and the United Kingdom have improved the prediction methods used to determine which strains of the flu virus to include in the current season's vaccine.

OTTAWA, Canada – October 1, 2012 – Being obese at any age is commonly associated with a litany of health issues, ranging from diabetes and chronic fatigue to heart complications. Overweight adolescents are also at an increased risk of body dissatisfaction, social alienation and low self esteem, which is why Dr.