Body

Scientists at Queen's University Belfast have developed a new technique which has the potential to kill off hospital superbugs like Pseudomonas aeruginosa, C. difficile and MRSA.

A current focus in global health research is to make medical tests that are not just cheap but virtually free. One such strategy is to start with paper – one of humanity's oldest technologies – and build a device like a home-based pregnancy test that might work for malaria, diabetes or other diseases.

A University of Washington bioengineer recently developed a way to make regular paper stick to medically interesting molecules. The work produced a chemical trick to make paper-based diagnostics using plain paper, the kind found at office supply stores around the world.

Researchers in Argentina report that women with multiple sclerosis (MS) who undergo assisted reproduction technology (ART) infertility treatment are at risk for increased disease activity. Study findings published in Annals of Neurology, a journal of the American Neurological Association and Child Neurology Society, suggest reproductive hormones contribute to regulation of immune responses in autoimmune diseases such as MS.

Boston, Mass.—Surgeons at Boston Children's Hospital have successfully implanted a modified version of an expandable prosthetic heart valve in several children with mitral valve disease. Unlike traditional prosthetic valves that have a fixed diameter, the expandable valve can be enlarged as a child grows, thus potentially avoiding the repeat valve replacement surgeries that are commonly required in a growing child. The new paradigm of expandable mitral valve replacement has potential to revolutionize care for infants and children with complex mitral valve disease.

Drug resistance is a major problem when treating infections. This problem is multiplied when the infection, like HIV-1, is chronic. New research published in BioMed Central's open access journal Retrovirology has examined the genetic footprint that drug resistance causes in HIV and found compensatory polymorphisms that help the resistant virus to survive.

Children in smaller families are only slightly more likely to survive childhood in high mortality environments, according to a new study of mothers and children in sub-Saharan Africa seeking to understand why women, even in the highest fertility populations in world, rarely give birth to more than eight children.

A new scientific report out today from the International Scientific Forum on Home Hygiene (IFH) dismantles the myth that the epidemic rise in allergies in recent years has happened because we're living in sterile homes and overdoing hygiene.

CHICAGO—Regenerative-medicine researchers have moved a promising step closer to helping infertile, premenopausal women produce enough eggs to become pregnant. Today, surgeons at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine in Winston-Salem, NC, reported that they were able to stimulate ovarian cell production using an in vitro rat model, and observed as the cells matured into very early-stage eggs that could possibly be fertilized. Results from this novel study were presented at the 2012 American College of Surgeons Annual Clinical Congress.

Indoor tanning increases the risks of developing non-melanoma skin cancer (known as basal cell carcinoma and squamous cell carcinoma), particularly among those exposed before the age of 25, finds a study published on bmj.com today.

It follows a BMJ study published in July that showed 3,438 (5.4%) new cases of melanoma diagnosed each year in Western Europe are related to sunbed use, particularly among young adults.

Leading doctors are calling for action to tackle unnecessary care that is estimated to account for up to $800bn in the United States every year.

In a special report for this week's BMJ, journalist Jeanne Lenzer describes how a new movement led by prominent doctors is challenging the basic assumption in US healthcare that more is better.

A new type of firework caused severe eye injuries and blindness in children and adults at last year's bonfire night celebrations, warn doctors in a letter to this week's BMJ.

Edward Pringle and colleagues describe how on the evening of 5 November 2011, eight patients attended the Sussex Eye Hospital, five with serious eye injuries - two were blinded and the other three have a lifelong glaucoma risk.

Indoor tanning beds can cause non-melanoma skin cancer – and the risk is greater the earlier one starts tanning, according to a new analysis led by UCSF.

Indoor tanning is already an established risk factor for malignant melanoma, the less common but deadliest form of skin cancer. Now, the new study confirms that indoor tanning significantly increases the risk of non-melanoma skin cancers, the most common human skin cancers.

Both obesity and under-nutrition are common in women and children from the Western Sahara living in refugee camps in Algeria, highlighting the need to balance both obesity prevention and management with interventions to tackle under-nutrition in this population, according to a study by international researchers published in this week's PLOS Medicine.

TALLAHASSEE, Fla. - Despite a shared Latino heritage, there are significant differences in the overall health and the use of health-care services among Cuban-Americans, Mexican-Americans and Puerto Rican-Americans — even between men and women in the same subgroup — according to two recently published studies by Florida State University researchers.

LOS ANGELES (Oct. 2, 2012) – Researchers at Cedars-Sinai's Maxine Dunitz Neurosurgical Institute have found that a blood vessel-building gene boosts the ability of human bone marrow stem cells to sustain pancreatic recovery in a laboratory mouse model of insulin-dependent diabetes.

The findings, published in a PLOS ONE article of the Public Library of Science, offer new insights on mechanisms involved in regeneration of insulin-producing cells and provide new evidence that a diabetic's own bone marrow one day may be a source of treatment.