Body

Bicycle infrastructure can reduce risk of cycling injuries by half: UBC study

Certain types of routes carry much lower risk of injury for cyclists, according to a new University of British Columbia study on the eve of Vancouver's Bike to Work Week.

The study, published today in the American Journal of Public Health, analyzed the cause of 690 cycling injuries in Vancouver and Toronto from 2008 to 2009 and various route types and infrastructure.

Study succeeds in cutting inappropriate antibiotic prescribing by pediatricians

San Diego, CA (October 18, 2012) – A study involving one of the nation's largest networks of pediatric practices was able to nearly halve the inappropriate use of antibiotics through quarterly monitoring and feedback of the physicians' prescribing patterns. The research, which is being presented at IDWeek, is one of the first to look at an antimicrobial stewardship intervention in the outpatient setting.

First-of-its-kind self-assembled nanoparticle for targeted and triggered thermo-chemotherapy

Boston, MA— Excitement around the potential for targeted nanoparticles (NPs) that can be controlled by stimulus outside of the body for cancer therapy has been growing over the past few years. More specifically, there has been considerable attention around near-infrared (NIR) light as an ideal method to stimulate nanoparticles from outside the body. NIR is minimally absorbed by skin and tissue, has the ability to penetrate deep tissue in a noninvasive way and the energy from NIR light can be converted to heat by gold nanomaterials for effective thermal ablation of diseased tissue.

Conservation scientists look beyond greenbelts to connect wildlife sanctuaries

We live in a human-dominated world. For many of our fellow creatures, this means a fragmented world, as human conduits to friends, family, and resources sever corridors that link the natural world. Our expanding web of highways, cities, and intensive agriculture traps many animals and plants in islands and cul-de-sacs of habitat, held back by barriers of geography or architecture from reaching mates, food, and wider resources.

High levels of hormones during pregnancy associated with higher risk for HR-negative breast cancer

ANAHEIM, Calif. — Increased concentrations of the pregnancy hormones estradiol and progesterone were associated with an increased risk for hormone receptor-negative breast cancer diagnosed before age 50, according to the results of a nested case-control study presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012.

Team support for cessation in the workplace helped motivate cigarette smokers to quit

ANAHEIM, Calif. —When smoking co-workers in the same team are placed on a cessation program, providing financial incentives to the team collectively in return for success of the smokers in the cessation program helped the smokers to quit smoking and remain abstinent for 12 months, according to data presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012.

Blood hormone levels predicted long-term breast cancer risk for postmenopausal women

ANAHEIM, Calif. — Blood hormone tests predicted a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to data from the Nurses' Health Study presented at the 11th Annual AACR International Conference on Frontiers in Cancer Prevention Research, held here Oct. 16-19, 2012.

Mechanisms of action for green tea extract in breast cancer prevention identified

ANAHEIM, Calif. — An oral green tea extract, Polyphenon E, appears to inhibit vascular endothelial growth factor and hepatocyte growth factor, both of which promote tumor cell growth, migration and invasion.

Blood hormone levels can predict long-term breast cancer risk

BOSTON, MA—Blood hormone tests can predict a woman's risk for developing postmenopausal breast cancer for up to 20 years, according to a study led by Xuehong Zhang, MD, Channing Division of Network Medicine, Brigham and Women's Hospital (BWH) Department of Medicine.

The findings will be presented at the 11th Annual American Association for Cancer Research (AACR) International Conference on Frontiers in Cancer Prevention Research.

'Time-capsule' Japanese lake sediment advances radiocarbon dating for older objects

A new series of radiocarbon measurements from Japan's Lake Suigetsu will give scientists a more accurate benchmark for dating materials, especially for older objects, according to a research team that included Oxford University's Radiocarbon Accelerator Unit.

Japanese lake record improves radiocarbon dating

This release is available in Japanese.

A new series of radiocarbon measurements from Japan's Lake Suigetsu should help make radiocarbon dating more precise and accurate, especially for older objects, researchers report.

Rutgers researchers unveil 3-D structure of 'molecular machine' that initiates DNA transcription

NEW BRUNSWICK, N.J. – An team of Rutgers University scientists led by Richard H. Ebright and Eddy Arnold has determined the three-dimensional structure of the transcription initiation complex, the key intermediate in the process by which cells read out genetic information in DNA.

Tropical collapse caused by lethal heat

Scientists have discovered why the 'broken world' following the worst extinction of all time lasted so long – it was simply too hot to survive.

The end-Permian mass extinction, which occurred around 250 million years ago in the pre-dinosaur era, wiped out nearly all the world's species. Typically, a mass extinction is followed by a 'dead zone' during which new species are not seen for tens of thousands of years. In this case, the dead zone, during the Early Triassic period which followed, lasted for a perplexingly long period: five million years.

Study shows breastfeeding reduced risk for ER/PR-negative breast cancer

October 18, 2012 -- Breast-feeding reduces the risk for estrogen receptor-negative and progesterone receptor-negative breast cancer, according to a study conducted at Columbia University's Mailman School of Public Health. Researchers examined the association between reproductive risk factors — such as the number of children a woman delivers, breast-feeding and oral contraceptive use – and found an increased risk for estrogen receptor- and progesterone receptor- (ER/PR) negative breast cancer in women who do not breast-feed.

Study shows elevated risk of blood clots in women taking birth control containing drospirenone

OAKLAND, Calif., Oct. 18— A U.S. Food and Drug Administration-funded study led by the Kaiser Permanente Northern California Division of Research found an increased risk of arterial thrombotic events (ATE) and venous thromboembolic events (VTE) — commonly referred to as blockage of arteries and blood clots, respectively — associated with drospirenone-containing birth control pills compared to four low-dose estrogen combined hormonal contraceptives.

The study appears in the current online issue of Contraception.