Body

Longer use of hormonal contraception during midlife predicts better cognitive function later

New Rochelle, NY, November 7, 2012—Premenopausal use of hormonal contraceptives may improve the cognitive abilities of women in midlife and for years afterward. This finding may have implications for prevention of declining cognitive function that occurs with advancing age and in diseases such as Alzheimer's. The beneficial effects of hormones increase the longer a woman uses them, as described in a study published in Journal of Women's Health, a peer-reviewed publication from Mary Ann Liebert, Inc., publishers.

Development of measures to prevent wine indispositions

Biogenic amines may be one of the factors responsible for symptoms such as headaches, gastro-intestinal disorders, shortness of breath, fall in blood pressure, and even unconsciousness and cardiac arrhythmia in severe cases. Histamine, one of the best known members of this group, can cause serious physical problems. Biogenic amines can be produced in the body by natural metabolic activities but are also ingested in larger quantities with food. They play a special role in microbiologically produced food such as wine, beer, cheese, and sauerkraut.

City birds adapt to their new predators

Faced with the same threat, city and country birds do not react in the same way despite being from the same species. According to a new study, urban birds have changed their anti-predator behaviour in new environments.

When a bird is faced with a predator, its only objective is to escape. However, city birds do not react in the same way as their countryside counterparts, despite being from the same species. Urbanisation plays an influential role in their survival strategies.

Protein reveals diabetes risk many years in advance

When a patient is diagnosed with type 2 diabetes, the disease has usually already progressed over several years and damage to areas such as blood vessels and eyes has already taken place. To find a test that indicates who is at risk at an early stage would be valuable, as it would enable preventive treatment to be put in place.

Researchers at Lund University have now identified a promising candidate for a test of this kind. The findings have been published in the journal Cell Metabolism.

In the digital age, managers can't ignore #angrycustomers

CHESTNUT HILL, MA (November 7, 2012) – In a digital age where dissatisfied consumers vent their concerns through biting viral videos, nasty blog posts or negative online comments, managers need to develop strategies to soothe angry customers in person as well as online, according to a new study in the latest edition of the Journal of Service Research.

Inflammation marker linked to increased risk for death from cancer in Korean men

PHILADELPHIA — Measuring blood levels of high-sensitive C-reactive protein, an important marker of inflammation, in apparently cancer-free men could potentially help identify those at increased risk for death from cancer, in particular lung cancer, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

Study reveals declining influence of high impact factor journals

The most prestigious peer-reviewed journals in the world, such as Cell, Nature, Science, and the Journal of the American Medical Association (JAMA), have less and less influence amongst scientists, according to a paper co-authored by Vincent Larivière, a professor at the University of Montreal's School of Library and Information Sciences. He questions the relationship between journal "impact factor" and number of citations subsequently received by papers.

DNA sequencing of infants and children with anatomical defects of unknown causes

A presentation at the American Society of Human Genetics 2012 meeting updated genetics experts about a one-year-old research initiative that brought together researchers, clinicians and policy experts to tackle the challenges of incorporating new genomic technologies into clinical care of newborns, infants and children with anatomical defects whose causes are unknown.

Humans, chimpanzees and monkeys share DNA but not gene regulatory mechanisms

Humans share over 90% of their DNA with their primate cousins. The expression or activity patterns of genes differ across species in ways that help explain each species' distinct biology and behavior.

DNA factors that contribute to the differences were described on Nov. 6 at the American Society of Human Genetics 2012 meeting in a presentation by Yoav Gilad, Ph.D., associate professor of human genetics at the University of Chicago.

New method helps link genomic variation to protein production

Scientists have adopted a novel laboratory approach for determining the effect of genetic variation on the efficiency of the biological process that translates a gene's DNA sequence into a protein, such as hemoglobin, according to a presentation, Nov. 6, at the American Society of Human Genetics 2012 meeting in San Francisco.

In the 0.1% of the DNA that differs between any two individuals, scientists search for the biological mechanisms underlying human genetic differences, including disease susceptibility.

Mothers’ age at menopause may predict daughters’ ovarian reserve

A mother's age at menopause may predict her daughter's fertility in terms of the numbers of eggs remaining in her ovaries, according to the new research published online in Europe's leading reproductive medicine journal Human Reproduction [1] today.

Scientists test 5,000 combinations of 100 existing cancer drugs to find more effective treatments

Scientists in the United States have tested all possible pairings of the 100 cancer drugs approved for use in patients in order to discover whether there are any combinations not tried previously that are effective in certain cancers.

New monoclonal antibody inhibits tumor growth in advanced solid tumors in phase I clinical trial

A newly developed antibody targeting a signalling pathway that is frequently active in solid tumours has shown encouraging signs of efficacy in its first trial in humans, researchers will report at the 24th EORTC-NCI-AACR [1] Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland, today (Wednesday). [2]

Strong tobacco control policies in Brazil credited for more than 400,000 lives saved

WASHINGTON – High cigarette prices, smoke-free air laws, marketing restrictions and other measures, all part of Brazil's strong tobacco control policies, are credited for a 50 percent reduction in smoking prevalence between 1989 and 2010. The reduction contributed to an estimated 420,000 lives saved during that time period. Those are the findings of a new study published today in PLOS Medicine by a team of researchers from Georgetown Lombardi Comprehensive Cancer Center and the Brazilian National Cancer Institute.

Regular physical activity increases life expectancy even if overweight

People who do regular physical activity, such as brisk walking, live longer than those who don't do any leisure time exercise, even when overweight, reports a study by international researchers published in this week's PLOS Medicine.

These findings are important because, according to the authors (led by Steven Moore from the National Cancer Institute in Bethesda, USA): "This finding may help convince currently inactive persons that a modest physical activity program is ''worth it'' for health benefits, even if it may not result in weight control."