Body

St. Joseph's researchers identify gene involved in lung tumor growth

(Phoenix, AZ Nov. 27, 2012) – Lung cancer researchers at St. Joseph's Hospital and Medical Center in Phoenix, Ariz., in collaboration with researchers at the Translational Genomics Research Institute and other institutions, have identified a gene that plays a role in the growth and spread of non-small cell lung cancer tumors, opening the door for potential new treatment options.

Garbage bug may help lower the cost of biofuel

One reason that biofuels are expensive to make is that the organisms used to ferment the biomass cannot make effective use of hemicellulose, the next most abundant cell wall component after cellulose. They convert only the glucose in the cellulose, thus using less than half of the available plant material.

Proteins that work at the ends of DNA could provide cancer insight

CHAMPAIGN, lll. — New insights into a protein complex that regulates the very tips of chromosomes could improve methods of screening anti-cancer drugs.

Led by bioengineering professor Sua Myong, the research group's findings are published in the journal Structure.

Marketing analytics ups Fortune 1000 return on assets 8 percent, says operations research study

Fortune 1000 companies that increase their use of marketing analytics improve their return on assets an average 8% and as much as 21%, with returns ranging from $70 million to $180 million in net income, according to a paper written by two key members of the Institute for Operations Research and the Management Sciences (INFORMS®).

Activating ALC1: With a little help from friends

KANSAS CITY, MO –Chromatin remodeling—the packaging and unpackaging of genomic DNA and its associated proteins—regulates a host of fundamental cellular processes including gene transcription, DNA repair, programmed cell death as well as cell fate. In their latest study, scientists at the Stowers Institute for Medical Research are continuing to unravel the finicky details of how these architectural alterations are controlled.

Molecular root of 'exhausted' T cells in chronic viral infection

PHILADELPHIA - When you get an acute infection, such as influenza, the body generally responds with a coordinated response of immune-cell proliferation and attack that rapidly clears the pathogen. Then, their mission done, the immune system stands down, leaving a population of sentinel memory cells to rapidly redeploy the immune system in the event of reinfection.

This is why vaccination works, and it's why, in theory at least, people who have had the chicken pox once will never get it again.

Harvard's Wyss Institute team creates versatile 3d nanostructures using DNA 'bricks'

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have created more than 100 three-dimensional (3D) nanostructures using DNA building blocks that function like Lego® bricks — a major advance from the two-dimensional (2D) structures the same team built a few months ago.

Jigsaw a critical piece of the Notch puzzle

HOUSTON -- (Nov. 30, 2012) – The Notch signaling pathway helps determine cell fate determination, differentiation and proliferative ability of numerous cells.

Clearest evidence yet of polar ice losses

An international team of satellite experts has produced the most accurate assessment of ice losses from Antarctica and Greenland to date, ending 20-years of uncertainty.

In a landmark study, published on 30 November in the journal Science, the researchers show that melting of the Antarctic and Greenland ice sheets has contributed 11.1 millimetres to global sea levels since 1992. This amounts to one fifth of all sea level rise over the survey period.

About two thirds of the ice loss was from Greenland, and the remainder was from Antarctica.

X-rays expose blueprint for possible sleeping sickness drug

X-ray laser helps fight sleeping sickness

An international group of scientists working at the Department of Energy's (DOE) SLAC National Accelerator Laboratory has mapped a weak spot in the parasite that causes African sleeping sickness, pinpointing a promising new target for treating a disease that kills tens of thousands of people each year.

A human-caused climate change signal emerges from the noise

Livermore, Calif. -- By comparing simulations from 20 different computer models to satellite observations, Lawrence Livermore climate scientists and colleagues from 16 other organizations have found that tropospheric and stratospheric temperature changes are clearly related to human activities.

Delayed treatment for advanced breast cancer has 'profound effect'

COLUMBUS, Ohio – Results from a new study conducted by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James) show women who wait more than 60 days to begin treatment for advanced breast cancer face significantly higher risks of dying than women who start therapy shortly after diagnosis.

Diabetics with cancer dangerously ignore blood sugar

CHICAGO --- When people with Type 2 diabetes are diagnosed with cancer -- a disease for which they are at higher risk -- they ignore their diabetes care to focus on cancer treatment, according to new Northwestern Medicine® research. But uncontrolled high blood sugar is more likely to kill them and impairs their immune system's ability to fight cancer.

Young surgeons face special concerns with operating room distractions

CORVALLIS, Ore. – A study has found that young, less-experienced surgeons made major surgical mistakes almost half the time during a "simulated" gall bladder removal when they were distracted by noises, questions, conversation or other commotion in the operating room.

In this analysis, eight out of 18, or 44 percent of surgical residents made serious errors, particularly when they were being tested in the afternoon. By comparison, only one surgeon made a mistake when there were no distractions.