Body

UNIVERSITY PARK, Pa. -- Not all video game players are destined for lives filled with failing relationships and dwindling friendships, according to Penn State researchers, who say that a lot depends on the role of the game-playing activity in the gamer's life.

"There's a common stereotype that if you play video games, then you are a loner," said Benjamin Hickerson, assistant professor of recreation, parks and tourism management. "But it may have more to do with how a person is involved in gaming that determines how their social support is affected."

St. Louis, MO – December 18, 2012 – Researchers at Aldrich Materials Science, a strategic technology initiative of Sigma-Aldrich Corporation (NASDAQ:SIAL) have discovered an innovative way to design an important class of three-dimensional (3D) hybrid structures, Metal Organic Frameworks (MOFs), under completely liquid-free conditions. High purity MOF products prepared by the liquid-free process may be ideally suited as rare earth containing materials for sensors and detectors, electronic or magnetic materials.

A researcher with the Faculty of Medicine & Dentistry and the Mazankowski Alberta Heart Institute is looking closely at a molecule linked to aortic aneurysms in the abdomen, and her findings could lead to a treatment to reduce swelling of the aortic artery, which would be a life-saving treatment.

Genes implicated in autism and other human diseases are prone to frequent mutations, according to a study published by Cell Press on December 20th in the journal Cell. The study suggests that elevated mutation rates in certain parts of the genome contribute to disease risk in humans.

"Some disease-related genes are gluttons for punishment," says senior study author Jonathan Sebat of the University of California, San Diego. "Despite the fact that these genes are important for normal human development, they appear to be getting hammered with mutations."

An international team, led by researchers from the University of California, San Diego School of Medicine, has discovered that "random" mutations in the genome are not quite so random after all. Their study, to be published in the journal Cell on December 21, shows that the DNA sequence in some regions of the human genome is quite volatile and can mutate ten times more frequently than the rest of the genome. Genes that are linked to autism and a variety of other disorders have a particularly strong tendency to mutate.

KANSAS CITY, MO – For a tiny embryo to grow into an entire fruit fly, mouse or human, the correct genes in each cell must turn on and off in precisely the right sequence. This intricate molecular dance produces the many parts of the whole creature, from muscles and skin to nerves and blood.

So what are the underlying principles of how those genes are controlled and regulated?

SAN FRANCISCO, CA—December 20, 2012—Scientists at the Gladstone Institutes have mapped the molecular mechanism by which a virus known as cytomegalovirus (CMV) so successfully infects its hosts. This discovery paves the way for new research avenues aimed at fighting this and other seemingly benign viruses that can turn deadly.

We use many different types of chemicals and plastics for the convenience of our everyday life. The current sources of these materials are provided from petrochemical industry, using fossil oil as a raw material. Due to our increased concerns on the environmental problems and fossil resource availability, there has been much interest in producing those chemicals and materials from renewable non-food biomass through biorefineries.

PITTSBURGH, Dec. 20, 2012 – Women deficient in vitamin D early in their pregnancies are more likely to deliver babies with lower birth weights, University of Pittsburgh Graduate School of Public Health research reveals.

The study, funded by the National Institutes of Health, will be reported in the January print edition of the Journal of Clinical Endocrinology & Metabolism and is now available online.

PHILADELPHIA—Researchers at the Kimmel Cancer Center at Jefferson (KCC) (insert link to "Kimmel Cancer Center at Jefferson" www.kimmelcancercenter.org) have developed potentially game-changing diagnostic and prognostic genetic tests shown to better predict prostate cancer survival outcomes and distinguish clinically-relevant cancers.

As the human population increases, so too do the demands and stresses on agriculture. In the January 2013 issue of International Journal of Plant Sciences, Penn State University Waller Professor of Plant Biology Dr. Sarah Assmann explores how the responses to environmental stresses by one small, genetically diverse plant species might illuminate possible approaches to addressing growing human demand for crop products amid decreasing resources.

A University of Colorado Cancer Center study in this month's edition of the Journal of Investigative Dermatology describes a new target and potential treatment for melanoma, the most dangerous form of skin cancer. MicroRNA can decide which genes in a cell's DNA are expressed and which stay silent. Melanoma tends to lack microRNA-26a, which makes the gene SODD go silent.

Some European wolves have a distinct preference for wild boar over other prey, according to new research.

Scientists from Durham University, UK, in collaboration with the University of Sassari in Italy, found that the diet of wolves was consistently dominated by the consumption of wild boar which accounted for about two thirds of total prey biomass, with roe deer accounting for around a third.

CAMBRIDGE, Mass. -- In most cities, traffic growth has outpaced road capacity, leading to increased congestion, particularly during the morning and evening commutes. In 2007, congestion on U.S. roads was responsible for 4.2 billion hours of additional travel time, as well as 2.8 billion gallons of fuel consumption and an accompanying increase in air pollution.