Body

Researchers discover gene that causes obesity in mice

AURORA, Colo. (March 5, 2013) – Researchers have discovered that deleting a specific gene in mice prevents them from becoming obese even on a high fat diet, a finding they believe may be replicated in humans.

"When fed a diet that induces obesity these mice don't get fat," said Prof. James McManaman, Ph.D., lead author of the study and vice-chairman of research for Obstetrics and Gynecology at the University of Colorado School of Medicine. "It may be possible to duplicate this in humans using existing technology that targets this specific gene."

Remains of extinct giant camel discovered in High Arctic by Canadian Museum of Nature

Ottawa, Canada, March 5, 2013 - A research team led by the Canadian Museum of Nature has identified the first evidence for an extinct giant camel in Canada's High Arctic. The discovery is based on 30 fossil fragments of a leg bone found on Ellesmere Island, Nunavut and represents the most northerly record for early camels, whose ancestors are known to have originated in North America some 45 million years ago.

Ancient DNA solves 320-year-old mystery

University of Adelaide researchers have found the answer to one of natural history's most intriguing puzzles – the origins of the now extinct Falkland Islands wolf and how it came to be the only land-based mammal on the isolated islands – 460km from the nearest land, Argentina.

Previous theories have suggested the wolf somehow rafted on ice or vegetation, crossed via a now-submerged land bridge or was even semi-domesticated and transported by early South American humans.

Novel small molecules used to visualize prostate cancer

Two novel radiolabeled small molecules targeting prostate-specific membrane antigen (PSMA) have excellent potential for further development as diagnostic and therapeutic radiopharmaceuticals, according to research published this month in The Journal of Nuclear Medicine. The imaging agents—123I-MIP-1072 and 123I-MIP-1095—were shown to have a high sensitivity of lesion detection in bone, soft tissue and the prostate gland with minimal retention in non-target tissue.

Before and after: Ad placement should reflect cultural conceptions of time

Consumers respond more favorably to advertising when the placement of product images is consistent with the way they visualize time, according to a new study in the Journal of Consumer Research.

U of M researchers utilize genetically corrected stem cells to spark muscle regeneration

MINNEAPOLIS/ST. PAUL (March 5, 2013) – Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for Duchenne Muscular Dystrophy (DMD).

Comparison investing: Why are consumers more willing to take risks when they can compare products?

Consumers are more willing to take risks and accept delays in exchange for greater benefits when they are able to compare products, according to a new study in the Journal of Consumer Research.

Targeting diet products: Why are more independent consumers better at delaying gratification?

Product benefits that occur later in time are more likely to appeal to more independent consumers than to those who are more group or family oriented, according to a new study in the Journal of Consumer Research.

On the trail of mucus-eaters in the gut

The microbiology team of David Berry, Alexander Loy and Michael Wagner from the Faculty of Life Sciences, in collaboration with scientists at the Max F. Perutz Laboratories (University of Vienna and the Medical University of Vienna) and with the help of NanoSIMS technology, has for the first time succeeded in directly observing microorganisms feeding on the intestinal mucosa. The results of this research project appear in the current issue of the prestigious journal "Proceedings of the National Academy of Sciences" (PNAS).

Nurse migration in North and Central America strengthening health systems

International nurse migration is a multibillion-dollar global phenomenon. Historically, Mexicans and Central Americans have not played a significant part in the migration of nurses to the United States. A new report, Strengthening health systems in North and Central America: What role for migration?, sponsored by the Migration Policy Institute (MPI), seeks to draw attention to the cross-border migration in the Americas and suggests ways the migration could be managed to meet the demand for health care services in the region.

Is the iPad Creative? It depends on who's buying it

Encouraging consumers to feel ownership of products they haven't yet purchased can backfire because consumers tend to see themselves in the products they own, according to a new study in the Journal of Consumer Research.

"Companies assume that consumers who are made to feel ownership of a product prior to purchase will prefer it over competing products, but this can actually have the opposite effect and lead consumers to judge the product less favorably," write authors Liad Weiss and Gita V. Johar (both Columbia University).

Product promotion: When do emotional appeals trump celebrity spokespeople?

Emotional appeals could be more effective than celebrities when promoting products related to a consumer's identity, according to a new study in the Journal of Consumer Research.

Colonoscopy screening reduces risk of advanced colorectal cancer

Philadelphia - A new study led by a researcher at the Perelman School of Medicine at the University of Pennsylvania adds support to current medical recommendations stating that screening colonoscopy substantially reduces an average-risk adult’s likelihood of being diagnosed with advanced colorectal cancer (CRC) in either the right or left side of the colon.

Herbal defluoridation of drinking water

Researchers in India have developed a filter system based on a medicinal herb, which they say can quickly and easily remove "fluoride" from drinking water. The technology described in the March issue of the International Journal of Environmental Engineering uses parts of the plant Tridax procumbens as a biocarbon filter for the ion.

When good food goes bad

MARCH 5, 2013—Baltimore, MD—The Center for Biosecurity of UPMC today released online ahead of print a new report, When Good Food Goes Bad: Strengthening the US Response to Foodborne Disease Outbreaks. The authors analyzed existing data and studies on foodborne illness outbreak response, identified emerging trends, and interviewed dozens of federal and state-level officials and experts from industry, professional organizations, academia, and relevant international organizations.