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Missed opportunities to help smokers with mental illness

Although smoking prevalence has declined in the United Kingdom over recent decades, it has changed little among people with mental health disorders, remaining substantially higher than the national average. Yet a study published in the journal Addiction, presenting work carried out for a report released today by the Royal College of Physicians and Royal College of Psychiatrists called 'Smoking and Mental Health', suggests that general practitioners (GPs) are missing opportunities to help smokers with mental health disorders to quit.

Sea hares outsmart peckish lobsters with sticky opaline

Sea hares are not the favourite food choice of many marine inhabitants, and it's easy to see why when you find out about the chemical weapons they employ when provoked – namely, two unpalatable secretions, ink and opaline, which they squirt at unsuspecting peckish predators. However, while much is known about the consequences of purple ink secretion, how the whitish and viscous opaline outsmarts a potential predator remains unknown. Charles Derby from Georgia State University, USA, wondered whether opaline could decrease the activity of a predator's sensory system.

Childhood asthma tied to combination of genes and wheezing illness

About 90 percent of children with two copies of a common genetic variation and who wheezed when they caught a cold early in life went on to develop asthma by age 6, according to a study to be published March 28 by the New England Journal of Medicine.

Poultry probiotic cuts its coat to beat bad bacteria

A strain of probiotic bacteria that can fight harmful bacterial infections in poultry has the ability to change its coat, according to new findings from the Institute of Food Research.

The probiotic is currently being taken forward through farm-scale trials to evaluate how well it combats Clostridium perfringens – a cause of necrotic enteritis in poultry and the second most common cause of food poisoning in the UK

Diverse bacteria on fresh fruits, vegetables vary with produce type, farming practices

Fresh fruit and vegetables carry an abundance of bacteria on their surfaces, not all of which cause disease. In the first study to assess the variety of these non-pathogenic bacteria, scientists report that these surface bacteria vary depending on the type of produce and cultivation practices. The results are published March 27 in the open access journal PLOS ONE by Jonathan Leff and Noah Fierer at the University of Colorado, Boulder.

Insect pests more plentiful in hotter parts of city than in cooler areas

Higher temperatures in cities can be a key driver of insect pest outbreaks on trees in urban areas, according to research published March 27 in the open access journal PLOS ONE by Emily Meineke from North Carolina State University and colleagues from other institutions.

Moffitt Researchers help lead international efforts that find new genetic links to ovarian cancer

Researchers at Moffitt Cancer Center, including Center Director Thomas A. Sellers, Ph.D., M.P.H., and 17 other co-authors, have discovered four new regions of the genome that influence the risk for developing ovarian cancer, according to two Moffitt-led studies published in the March 27 issue of the journals Nature Genetics and Nature Communications.

Genetics might determine which smokers get hooked

DURHAM, N.C. -- Researchers have identified genetic risk factors that may accelerate a teen's progression to becoming a lifelong heavy smoker.

The team of scientists from the U.S., the U.K. and New Zealand examined earlier studies by other research teams to develop a genetic risk profile for heavy smoking. Then they looked at their own long-term study of 1,000 New Zealanders from birth to age 38 to identify whether individuals at high genetic risk got hooked on cigarettes more quickly as teens and whether, as adults, they had a harder time quitting.

Study finds anti-smoking drug improves smokers' chances of stopping

HOUSTON -– Smokers have a higher probability of quitting smoking and a better overall cessation experience when taking varenicline compared to bupropion and to placebo – unmedicated assisted smoking cessation –according to a study published in the journal JAMA Psychiatry.

Cancer biologists find DNA-damaging toxins in common plant-based foods

In a laboratory study pairing food chemistry and cancer biology, scientists at the Johns Hopkins Kimmel Cancer Center tested the potentially harmful effect of foods and flavorings on the DNA of cells. They found that liquid smoke flavoring, black and green teas and coffee activated the highest levels of a well-known, cancer-linked gene called p53.

The p53 gene becomes activated when DNA is damaged. Its gene product makes repair proteins that mend DNA. The higher the level of DNA damage, the more p53 becomes activated.

New bone survey method could aid long-term survival of Arctic caribou

GAINESVILLE, Fla. — A study co-authored by a University of Florida scientist adds critical new data for understanding caribou calving grounds in an area under consideration for oil exploration in Alaska's Arctic National Wildlife Refuge.

The research may be used to create improved conservation strategies for an ecologically important area that has been under evaluation for natural resource exploration since enactment of the Alaska National Interest Lands Conservation Act in 1980.

The hunt for a successor to lithium for bipolar disorder

Toxicity problems and adverse side effects when taking lithium, the mainstay medication for treating bipolar disorder, are fostering a scientific hunt for insights into exactly how lithium works in the body — with an eye to developing a safer alternative. That's the topic of the cover story in the current edition of Chemical & Engineering News. C&EN is the weekly newsmagazine of the American Chemical Society, the world's largest scientific society.

University of Tennessee professor discovers how microbes survive at bare minimum

Beneath the ocean floor is a desolate place with no oxygen and sunlight. Yet microbes have thrived in this environment for millions of years.

Scientists have puzzled over how these microbes survive, but today there are more answers.

A study led by Karen Lloyd, a University of Tennessee, Knoxville, assistant professor of microbiology, reveals that these microscopic life-forms called archaea slowly eat tiny bits of protein. The study was released today in Nature.

Certain breast cancers have a trait that could be attacked by new therapies

More than 100 women per day die from breast cancer in the United States. The odds of developing breast cancer increase for women taking hormone replacement therapy to avoid the effects of menopause. New research by University of Missouri scientist Salman Hyder may lead to treatments for breast cancers associated with taking these synthetic hormones. Hyder, along with an international team, found that hormone-therapy-related breast cancer cells have a physical feature that could be attacked by cancer therapies.

Changes in gastrointestinal microbes may produce some benefits of gastric bypass

Changes in the population of microbial organisms in the gastrointestinal tract may underlie some of the benefits of gastric bypass surgery, reports a team of researchers from Massachusetts General Hospital (MGH) and Harvard University.