Body

Physicians ask EPA, 'Antibiotics to cure sick apples, or sick children?'

Arlington, VA—A federal decision to permit the State of Michigan to spray the state's apple orchards with gentamicin risks undermining the value of this important antibiotic to treat blood infections in newborns and other serious human infections, according to the Infectious Diseases Society of America (IDSA).

The Environmental Protection Agency (EPA) on Wednesday granted the state of Michigan "emergency" permission to use gentamicin to fight a tree disease called fire blight.

How 'hidden mutations' contribute to HIV drug resistance

One of the major reasons that treatment for HIV/AIDS often doesn't work as well as it should is resistance to the drugs involved. Now, scientists at McGill University have revealed how mutations hidden in previously ignored parts of the HIV genome play an important role in the development of drug resistance in AIDS patients. Their study will be published Aug. 8 in the Journal of Biological Chemistry.

Spanish researchers take part in the discovery of a new immune disease

From the moment we are born, we all come into continuous contact with microbes that can cause disease. To deal with them, we have a highly effective immune system that allows our bodies to identify and eliminate agents that cause infections. Part of this mechanism is innate (already present at the time of birth) and the remaining part improves as we come into contact with new pathogens.

Stanford fruit-fly study adds weight to theories about another type of adult stem cell

STANFORD, Calif. - It turns out that an old dog - or at least an old fruit-fly cell - can learn new tricks. Researchers at the Stanford University School of Medicine have found that mature, specialized cells naturally regress to serve as a kind of de facto stem cell during the fruit-fly life cycle.

The surprising discovery counters the common belief that the ability to form new cell types or tissues wanes as a cell becomes more specialized.

Water refineries?

Using a surprisingly simple, inexpensive technique, chemists have found a way to pull pure oxygen from water using relatively small amounts of electricity, common chemicals and a room-temperature glass of water.

Because oxygen and hydrogen are energy-rich fuels, many researchers have proposed using solar electricity to split water into those elements--a stored energy source for when the sun goes down. One of the chief obstacles to that green-energy scenario has been the difficulty of producing oxygen without large amounts of energy or a high-maintenance environment.

Neurons created from skin cells of elderly ALS patients

Cambridge, MA, July 31, 2008 - Less than 27 months after announcing that he had institutional permission to attempt the creation of patient and disease-specific stem cell lines, Harvard Stem Cell Institute (HSCI) Principal Faculty member Kevin Eggan today proclaimed the effort a success - though politically imposed restrictions and scientific advances prompted him to use a different technique than originally planned.

Water refineries?

Using a surprisingly simple, inexpensive technique, chemists have found a way to pull pure oxygen from water using relatively small amounts of electricity, common chemicals and a room-temperature glass of water.

Because oxygen and hydrogen are energy-rich fuels, many researchers have proposed using solar electricity to split water into those elements--a stored energy source for when the sun goes down. One of the chief obstacles to that green-energy scenario has been the difficulty of producing oxygen without large amounts of energy or a high-maintenance environment.

Harvard-Columbia team creates neurons from ALS patient's skin cells

NEW YORK – Harvard and Columbia scientists have for the first time used a new technique to transform an ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease) patient's skin cells into motor neurons, a process that may be used in the future to create tailor-made cells to treat the debilitating disease. The research – led by Kevin Eggan, Ph.D. of the Harvard Stem Cell Institute – will be published July 31 in the online version of the journal Science.

NY Stem Cell Foundation plays critical funding role in major new ALS research announced today

NEW YORK, NY (July 31, 2008) – In a breakthrough discovery, Dr. Kevin Eggan, Chief Scientific Officer of The New York Stem Cell Foundation and Principal Faculty Member of the Harvard Stem Cell Institute, has produced human stem cell lines from the cells of patients afflicted with a version of amyotrophic lateral sclerosis (ALS), commonly known as Lou Gehrig's disease. Eggan's work marks the first time scientists have replicated in a laboratory the specific human cells affected by disease.

Monash fuels the next generation of hybrid cars

Monash University scientists have revolutionised the design of fuel cells used in the latest generation of hybrid cars which could make the vehicles more reliable and cheaper to build.

The breakthrough, published today in the journal Science, revolves around the design of a fuel cell in which a specially-coated form of popular hi tech outdoor and sporting clothing material Goretex® is the key component.

'Small' research at MSU leads to advances in energy, electronics

A Michigan State University researcher and his students have developed a nanomaterial that makes plastic stiffer, lighter and stronger and could result in more fuel-efficient airplanes and cars as well as more durable medical and sports equipment.

Simian foamy virus found in several people living and working with monkeys in Asia

A research team led by University of Washington scientists has found that several people in South and Southeast Asian countries working and living around monkeys have been infected with simian foamy virus (SFV), a primate virus that, to date, has not been shown to cause human disease. The findings provide more evidence that Asia, where interaction between people and monkeys is common and widespread, could be an important setting for future primate-to-human viral transmission. The study appears in the August issue of the journal Emerging Infectious Disease.

First performance-enhancing drugs for exercise endurance?

While steroids can help build the bulky muscles that lend athletes and body builders power and speed, there hadn't been a drug capable of building the endurance needed to run a marathon or to ride a bike through the Alps. Now, there just might be, suggests a new study in mice reported in the journal Cell, a Cell Press publication.

The report shows that a drug developed for the treatment of metabolic disease, when taken in combination with exercise, gives mice the ability to run farther than exercise training alone can.

Researchers identify drugs that enhance exercise endurance

Howard Hughes Medical Institute researchers have identified two drugs that mimic many of the physiological effects of exercise. The drugs increase the ability of cells to burn fat and are the first compounds that have been shown to enhance exercise endurance.

Exercise in a pill

LA JOLLA, CA — Trying to reap the health benefits of exercise? Forget treadmills and spin classes, researchers at the Salk Institute for Biological Studies may have found a way around the sweat and pain. They identified two signaling pathways that are activated in response to exercise and converge to dramatically increase endurance.